CA2910855C - Targeting o-acetylated gd2 ganglioside as a new therapeutic and diagnostic strategy for cancer stem cells cancer - Google Patents
Targeting o-acetylated gd2 ganglioside as a new therapeutic and diagnostic strategy for cancer stem cells cancer Download PDFInfo
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- CA2910855C CA2910855C CA2910855A CA2910855A CA2910855C CA 2910855 C CA2910855 C CA 2910855C CA 2910855 A CA2910855 A CA 2910855A CA 2910855 A CA2910855 A CA 2910855A CA 2910855 C CA2910855 C CA 2910855C
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- C07K16/3084—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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| PCT/EP2014/001142 WO2014177271A1 (en) | 2013-04-29 | 2014-04-29 | Targeting o-acetylated gd2 ganglioside as a new therapeutic and diagnostic strategy for cancer stem cells cancer |
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| EP3329937A1 (en) * | 2016-12-05 | 2018-06-06 | OGD2 Pharma | Use of antibody against o-acetylated gd2 ganglioside to improve the therapeutic potential of drugs |
| CN108948211B (zh) * | 2018-07-24 | 2021-08-20 | 北京美康基免生物科技有限公司 | 一种基于靶向gd2的嵌合抗原受体及其应用 |
| CN110551218B (zh) * | 2019-09-17 | 2021-03-30 | 达石药业(广东)有限公司 | 一种gd2纳米抗体及其应用 |
| EP4322937A1 (en) | 2021-04-14 | 2024-02-21 | Institut National de la Santé et de la Recherche Médicale (INSERM) | New method to improve the anti-tumoral activity of macrophages |
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| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
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| KR20110073534A (ko) * | 2008-10-22 | 2011-06-29 | 제넨테크, 인크. | 전립선 줄기 세포 및 그의 용도 |
| BRPI0921150B1 (pt) * | 2008-11-11 | 2022-05-10 | The Regents Of The University Of Michigan | Uso de um antagonista de cxcr1 para o tratamento de tumor |
| EP2332994A1 (en) * | 2009-12-09 | 2011-06-15 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Trispecific therapeutics against acute myeloid leukaemia |
| TWI535445B (zh) * | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Ｗｎｔ拮抗劑及治療和篩選方法 |
| CN102251013A (zh) * | 2011-02-22 | 2011-11-23 | 北京市肿瘤防治研究所 | 一个识别肿瘤起始细胞的抗体和抗原及其应用 |
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| AU2014261788B2 (en) | 2019-07-11 |
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| EP2992018A1 (en) | 2016-03-09 |
| EP2992018B1 (en) | 2019-02-13 |
| WO2014177271A1 (en) | 2014-11-06 |
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