CA2908613A1 - Filets moleculaires sur phases solides - Google Patents

Filets moleculaires sur phases solides

Info

Publication number
CA2908613A1
CA2908613A1 CA2908613A CA2908613A CA2908613A1 CA 2908613 A1 CA2908613 A1 CA 2908613A1 CA 2908613 A CA2908613 A CA 2908613A CA 2908613 A CA2908613 A CA 2908613A CA 2908613 A1 CA2908613 A1 CA 2908613A1
Authority
CA
Canada
Prior art keywords
analyte
molecular
molecular net
solid phase
capture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2908613A
Other languages
English (en)
Inventor
Emily Stein
Bruce Phelps
Robert PLACE
Dina UZRI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inoviq Inc
Original Assignee
SEVIDENT Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/938,055 external-priority patent/US9910040B2/en
Application filed by SEVIDENT Inc filed Critical SEVIDENT Inc
Publication of CA2908613A1 publication Critical patent/CA2908613A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

L'invention concerne une matrice tridimensionnelle multicouche liée par covalence comprenant des molécules de capture, des lieurs et des espaceurs (appelés filets moléculaires) pour une capture spécifique et sensible d'analyte d'un échantillon. L'invention concerne également un filet moléculaire comprenant une matrice tridimensionnelle multicouche liée par covalence comprenant plus d'un type de molécules de capture et plus d'un type de lieurs et pouvant comprendre un ou plusieurs espaceurs pour la capture spécifique et sensible de plus d'un type d'analytes d'un échantillon. Un filet moléculaire peut comprendre une nature pseudo-aléatoire. L'utilisation de diverses molécules de capture, de divers lieurs et espaceurs dans un filet moléculaire peut conférer des propriétés de liaison uniques à un filet moléculaire. La porosité, l'affinité de liaison, les capacités d'exclusion de taille, les capacités de filtration, les capacités de concentration et les capacités d'amplification de signal d'un filet moléculaire peuvent varier et dépendent de la nature des composants utilisés dans sa fabrication. Les utilisations d'un filet moléculaire peuvent comprendre la capture d'analyte, l'enrichissement d'analyte, la purification d'analyte, la détection d'analyte, la mesure d'analyte et la distribution d'analyte. Le filet moléculaire peut être utilisé dans une phase liquide ou sur des phases solides, telles que des nanomatériaux, des surfaces métalliques modifiées, des nanosphères, des microsphères, des plaques de microtitrage, des lames, des pipettes, des cassettes, des cartouches, des disques, des sondes, des dispositifs à écoulement latéral, des dispositifs de microfluide, des fibres optiques et d'autres.
CA2908613A 2013-03-14 2014-03-14 Filets moleculaires sur phases solides Pending CA2908613A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361783189P 2013-03-14 2013-03-14
US61/783,189 2013-03-14
US13/938,055 2013-07-09
US13/938,055 US9910040B2 (en) 2012-07-09 2013-07-09 Molecular nets comprising capture agents and linking agents
PCT/US2014/029823 WO2014153262A1 (fr) 2013-03-14 2014-03-14 Filets moléculaires sur phases solides

Publications (1)

Publication Number Publication Date
CA2908613A1 true CA2908613A1 (fr) 2014-09-25

Family

ID=51581466

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2908613A Pending CA2908613A1 (fr) 2013-03-14 2014-03-14 Filets moleculaires sur phases solides

Country Status (5)

Country Link
EP (1) EP2972343A4 (fr)
CN (2) CN110068677A (fr)
AU (1) AU2014236090B2 (fr)
CA (1) CA2908613A1 (fr)
WO (1) WO2014153262A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105930586B (zh) * 2016-04-21 2019-02-01 郑州轻工业学院 基于局域性dna发卡链置换反应的异或门及求反电路
CN107338185B (zh) * 2017-08-02 2019-07-30 昆山汇先医药技术有限公司 一种细胞或溶液中生物分子的捕获方法
WO2019023961A1 (fr) * 2017-08-02 2019-02-07 Suzhou Bofu Biomedical Limited Procédé de capture de cellules ou de molécules cibles en solution

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3116995A1 (de) * 1981-04-29 1982-11-25 Röhm GmbH, 6100 Darmstadt Latex zur immobilisierung von biologisch wirksamen substanzen
CZ286845B6 (cs) * 1995-03-27 2000-07-12 Ústav Makromolekulární Chemie Av Čr Způsob imobilizace bílkovin a polyelektrolytů na povrchu pevných objektů
US9201067B2 (en) * 2003-03-05 2015-12-01 Posco Size-controlled macromolecule
WO2003025573A1 (fr) * 2001-09-17 2003-03-27 Pharmacia Diagnostics Ab Dispositif de test multi-analytes a zone de detection multipoints
EP1461606A4 (fr) * 2001-12-05 2005-06-29 Univ Washington Dispositif microfluidique et procede de decoration de surface pour des dosages par liaison d'affinite en phase solide
US20030149246A1 (en) * 2002-02-01 2003-08-07 Russell John C. Macromolecular conjugates and processes for preparing the same
CN1882701B (zh) * 2003-09-18 2015-11-25 Posco公司 大小受控的大分子
US8101425B1 (en) * 2004-06-09 2012-01-24 Pathogen Removal And Diagnostic Technologies Inc. Particles embedded in a porous substrate for removing target analyte from a sample
WO2007067189A2 (fr) * 2004-12-20 2007-06-14 The Regents Of The University Of Colorado Systemes et procedes pour dosages biologiques
CN100420947C (zh) * 2005-05-30 2008-09-24 孙东旭 用单一捕获剂定量检测特异性分析物的方法及其试剂盒
EP1929299B1 (fr) * 2005-09-27 2010-12-22 George Mason Intellectual Properties, Inc. Methode d'isolement d'analytes provenant d'un echantillon
DK2308900T3 (da) * 2005-10-25 2014-05-12 Artificial Cell Technologies Inc Immunogene sammensætninger og fremgangsmåder til anvendelse
WO2007049269A1 (fr) * 2005-10-27 2007-05-03 Bio-Rad Haifa Ltd. Couche de liaison, procede destine a sa preparation et utilisations de celle-ci
CN103038639B (zh) * 2009-11-24 2017-03-29 赛维登特公司 用于检测分析物的装置
EP2541250A1 (fr) * 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Architecture moléculaire de particules magnétiques pour des analyses dýaffinité avec une faible liaison non spécifique
WO2014011673A2 (fr) * 2012-07-09 2014-01-16 Sevident, Inc. Filets moléculaires

Also Published As

Publication number Publication date
AU2014236090B2 (en) 2019-09-12
EP2972343A1 (fr) 2016-01-20
WO2014153262A1 (fr) 2014-09-25
CN105339791A (zh) 2016-02-17
CN105339791B (zh) 2019-02-15
AU2014236090A1 (en) 2015-10-08
CN110068677A (zh) 2019-07-30
EP2972343A4 (fr) 2016-08-24

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Effective date: 20190311

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