CA2894160C - Treating oral lesions using placental extracellular matrix - Google Patents

Treating oral lesions using placental extracellular matrix Download PDF

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Publication number
CA2894160C
CA2894160C CA2894160A CA2894160A CA2894160C CA 2894160 C CA2894160 C CA 2894160C CA 2894160 A CA2894160 A CA 2894160A CA 2894160 A CA2894160 A CA 2894160A CA 2894160 C CA2894160 C CA 2894160C
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CA
Canada
Prior art keywords
stem cells
cells
ecm
isolated
placental stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2894160A
Other languages
English (en)
French (fr)
Other versions
CA2894160A1 (en
Inventor
Robert J. Hariri
Jodi P. Gurney
Mohit B. Bhatia
Wolfgang Hofgartner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celularity Inc
Original Assignee
Celularity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celularity Inc filed Critical Celularity Inc
Publication of CA2894160A1 publication Critical patent/CA2894160A1/en
Application granted granted Critical
Publication of CA2894160C publication Critical patent/CA2894160C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA2894160A 2012-12-07 2013-12-06 Treating oral lesions using placental extracellular matrix Active CA2894160C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261734665P 2012-12-07 2012-12-07
US61/734,665 2012-12-07
PCT/US2013/073593 WO2014089440A1 (en) 2012-12-07 2013-12-06 Treating oral lesions using placental extracellular matrix

Publications (2)

Publication Number Publication Date
CA2894160A1 CA2894160A1 (en) 2014-06-12
CA2894160C true CA2894160C (en) 2024-01-02

Family

ID=50884026

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2894160A Active CA2894160C (en) 2012-12-07 2013-12-06 Treating oral lesions using placental extracellular matrix

Country Status (9)

Country Link
US (1) US20150313948A1 (https=)
EP (2) EP3838280A1 (https=)
JP (4) JP2016501245A (https=)
CN (2) CN104955465A (https=)
BR (1) BR112015013125A2 (https=)
CA (1) CA2894160C (https=)
HK (1) HK1215391A1 (https=)
RU (2) RU2019101641A (https=)
WO (1) WO2014089440A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2897625B1 (en) 2012-09-10 2019-10-23 Wake Forest University Health Sciences Amniotic membrane and its use in wound healing and tissue engineering constructs
SG10201901713RA (en) * 2014-08-25 2019-03-28 Hli Cellular Therapeutics Llc Extracellular matrix compositions
EP3200809B1 (en) * 2014-10-02 2023-09-13 Wake Forest University Health Sciences, Inc. Amniotic membrane powder and its use in wound healing and tissue engineering constructs
CN110095421B (zh) * 2019-05-17 2022-02-08 淮海工学院 一种胶原蛋白变性温度的测定方法
CN110975010B (zh) * 2019-11-25 2022-02-15 银丰低温医学科技有限公司 一种胎盘组织基质材料及其制备方法
CN111494223A (zh) * 2020-04-22 2020-08-07 福建汉氏联合干细胞科技有限公司 一种胎盘源干细胞漱口修复液
WO2025147712A1 (en) * 2024-01-05 2025-07-10 Viscus Biologics, Llc Xenogeneic oral repair compositions and implants thereof

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185011A (en) 1978-10-16 1980-01-22 Firma Carl Freudenberg Process for the production of collagen fibers
DE3042860A1 (de) 1980-11-13 1982-06-09 Heyl & Co Chemisch-Pharmazeutische Fabrik, 1000 Berlin Kollagenpraeparate, verfahren zu ihrer herstellung und ihre verwendung in der human- und veterinaermedizin
FR2516927B1 (fr) 1981-11-26 1986-05-23 Merieux Fond Procede de preparation industrielle de materiaux collageniques a partir de tissus placentaires humains, materiaux collageniques humains obtenus, leur application comme biomateriaux
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US5436135A (en) 1985-09-02 1995-07-25 Pasteur Merieux Serums Et Vaccins New preparation of placenta collagen, their extraction method and their applications
US4852640A (en) 1986-03-28 1989-08-01 Exothermics-Eclipse Inc. Recuperative heat exchanger
US5660692A (en) 1988-02-24 1997-08-26 Cedars-Sinai Medical Center Method of crosslinking amino acid-containing polymers using photoactivatable chemical crosslinkers
US5008116A (en) 1988-11-14 1991-04-16 Frederick Cahn Immunostimulatory microsphere
FR2692582B1 (fr) 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
US5428022A (en) 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen
FR2699184B1 (fr) 1992-12-16 1995-03-10 Flamel Tech Sa Nouveaux dérivés de collagène, leur procédé d'obtention et leur application à la préparation de biomatériaux.
CA2247199A1 (en) 1996-03-04 1997-09-12 Edwards Lifesciences Corporation Nonpolymeric epoxy compounds for cross-linking biological tissue and bioprosthetic grafts prepared thereby
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US6117979A (en) 1997-08-18 2000-09-12 Medtronic, Inc. Process for making a bioprosthetic device and implants produced therefrom
EP2305795B1 (en) 2000-12-06 2019-07-03 Celularity, Inc. Method of collecting placental stem cells
EP2316918B1 (en) 2001-02-14 2015-07-01 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
JP2003119157A (ja) * 2001-08-06 2003-04-23 Kikuji Yamashita コラーゲンを含有する洗口剤
US9084772B2 (en) 2001-08-31 2015-07-21 Orthopeutics L.P. Use of non-toxic crosslinking reagents to improve fatigue resistance and reduce mechanical degradation of intervertebral disc and other collagenous tissues
US20030124178A1 (en) * 2001-12-28 2003-07-03 Haley Jeffrey T. Soft, adherent, soluble oral patch
US20030187515A1 (en) * 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US20060134201A1 (en) * 2004-12-16 2006-06-22 Haley Jeffrey T Collagen troches for treating mouth lesions
US7928280B2 (en) * 2005-07-13 2011-04-19 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
PL2471907T3 (pl) 2005-12-29 2019-07-31 Celularity, Inc. Populacje komórek macierzystych łożyska
CN101622007A (zh) * 2006-10-06 2010-01-06 人类起源公司 天然(端肽)胎盘胶原组合物
DE502006006810D1 (de) * 2006-11-06 2010-06-02 Lohmann & Rauscher Gmbh & Co Produkt zur Versorgung von Entzündungen, Druckstellen und/oder Aphten im Oralbereich sowie Verwendung eines solchen Produkts
EP4559488A3 (en) * 2007-09-07 2025-08-13 MiMedx Group, Inc. Placental tissue grafts and improved methods of preparing and using the same
US9304134B2 (en) * 2010-11-23 2016-04-05 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of anemia

Also Published As

Publication number Publication date
HK1215391A1 (zh) 2016-08-26
JP2019108329A (ja) 2019-07-04
BR112015013125A2 (pt) 2017-07-11
JP2016501245A (ja) 2016-01-18
EP2928481A1 (en) 2015-10-14
JP2023065422A (ja) 2023-05-12
RU2019101641A (ru) 2019-03-20
EP2928481A4 (en) 2016-09-14
CA2894160A1 (en) 2014-06-12
CN104955465A (zh) 2015-09-30
WO2014089440A1 (en) 2014-06-12
CN117899116A (zh) 2024-04-19
RU2019101641A3 (https=) 2021-12-28
RU2015127077A (ru) 2017-01-12
JP2021073217A (ja) 2021-05-13
US20150313948A1 (en) 2015-11-05
EP3838280A1 (en) 2021-06-23

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