CA2887928A1 - Compound comprising a mao targeting/seeker moiety for treating human gliomas - Google Patents
Compound comprising a mao targeting/seeker moiety for treating human gliomas Download PDFInfo
- Publication number
- CA2887928A1 CA2887928A1 CA2887928A CA2887928A CA2887928A1 CA 2887928 A1 CA2887928 A1 CA 2887928A1 CA 2887928 A CA2887928 A CA 2887928A CA 2887928 A CA2887928 A CA 2887928A CA 2887928 A1 CA2887928 A1 CA 2887928A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- mao
- chemotherapeutic
- cells
- moiety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161553854P | 2011-10-31 | 2011-10-31 | |
| US61/553,854 | 2011-10-31 | ||
| PCT/US2012/062850 WO2013151584A1 (en) | 2011-10-31 | 2012-10-31 | Compound comprising a mao targeting/ seeker moiety for treating human gliomas |
Publications (1)
| Publication Number | Publication Date |
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| CA2887928A1 true CA2887928A1 (en) | 2013-10-10 |
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| CA2887928A Abandoned CA2887928A1 (en) | 2011-10-31 | 2012-10-31 | Compound comprising a mao targeting/seeker moiety for treating human gliomas |
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| EP (2) | EP2804604A1 (enExample) |
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| HK (1) | HK1204547A1 (enExample) |
| WO (1) | WO2013151584A1 (enExample) |
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| CN104136026B (zh) | 2011-10-31 | 2018-03-02 | 卫理公会医院研究所 | 包含mao靶向/探寻器部分的人神经胶质瘤治疗用化合物 |
| CN104710433B (zh) * | 2014-01-23 | 2016-08-17 | 南京友怡医药科技有限公司 | 苯丁酸氮芥衍生物、制备方法及应用 |
| WO2015153516A1 (en) * | 2014-04-04 | 2015-10-08 | University Of Florida Research Foundation | Hdac inhibitor compounds and methods of treatment |
| CN116917009A (zh) | 2021-02-19 | 2023-10-20 | 美国迈胜医疗系统有限公司 | 用于粒子治疗系统的机架 |
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| IE80468B1 (en) | 1995-04-04 | 1998-07-29 | Elan Corp Plc | Controlled release biodegradable nanoparticles containing insulin |
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| EP1165501A1 (en) | 1999-03-03 | 2002-01-02 | The Procter & Gamble Company | Alkenyl- and alkynyl-containing metalloprotease inhibitors |
| US6727361B2 (en) | 2000-11-07 | 2004-04-27 | Symyx Technologies, Inc. | Phosphino substituted pyridine amine ligands |
| US6946479B2 (en) | 2002-11-09 | 2005-09-20 | The Procter & Gamble Company | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones |
| US7943586B2 (en) | 2003-06-09 | 2011-05-17 | The Trustees Of The University Of Pennsylvania | Antineoplastic agents targeted via glut transporters |
| CA2564199A1 (en) * | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| US7091205B2 (en) | 2004-10-08 | 2006-08-15 | Yu Show Fu | Use of tetramethylpyrazine in the treatment of brain tumor |
| GB0513297D0 (en) | 2005-06-29 | 2005-08-03 | Glaxo Group Ltd | Novel compounds |
| US20070275944A1 (en) | 2006-04-05 | 2007-11-29 | The Board Of Trustees Operating Michigan State University | Antioxidants and methods of their use |
| AR070317A1 (es) * | 2008-02-06 | 2010-03-31 | Osi Pharm Inc | Furo (3,2-c) piridina y tieno (3,2-c) piridinas |
| MX2010009410A (es) * | 2008-02-29 | 2010-11-30 | Array Biopharma Inc | Compuestos del inhibidor de raf y métodos de uso de los mismos. |
| EP2141163A1 (de) * | 2008-07-02 | 2010-01-06 | Bayer Schering Pharma AG | Substituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel |
| TWI624457B (zh) * | 2009-06-10 | 2018-05-21 | 中外製藥股份有限公司 | 四環性化合物 |
| EP2480531B1 (en) * | 2009-09-21 | 2014-11-05 | ChemoCentryx, Inc. | Pyrrolidinone carboxamide derivatives as chemerin-r (chemr23) modulators |
| CN104136026B (zh) | 2011-10-31 | 2018-03-02 | 卫理公会医院研究所 | 包含mao靶向/探寻器部分的人神经胶质瘤治疗用化合物 |
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2012
- 2012-10-31 CN CN201280064763.1A patent/CN104136026B/zh not_active Expired - Fee Related
- 2012-10-31 AU AU2012376221A patent/AU2012376221A1/en not_active Abandoned
- 2012-10-31 HK HK15103179.0A patent/HK1204547A1/xx unknown
- 2012-10-31 CA CA2887928A patent/CA2887928A1/en not_active Abandoned
- 2012-10-31 JP JP2014540047A patent/JP6118808B2/ja not_active Expired - Fee Related
- 2012-10-31 EP EP12783818.3A patent/EP2804604A1/en not_active Withdrawn
- 2012-10-31 WO PCT/US2012/062850 patent/WO2013151584A1/en not_active Ceased
- 2012-10-31 EP EP20189611.5A patent/EP3815685A3/en not_active Withdrawn
- 2012-10-31 KR KR1020147014835A patent/KR102110794B1/ko active Active
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2014
- 2014-04-30 US US14/266,729 patent/US10555936B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN104136026B (zh) | 2018-03-02 |
| JP2014534227A (ja) | 2014-12-18 |
| KR20140128943A (ko) | 2014-11-06 |
| EP2804604A1 (en) | 2014-11-26 |
| US20140323513A1 (en) | 2014-10-30 |
| EP3815685A2 (en) | 2021-05-05 |
| KR102110794B1 (ko) | 2020-05-15 |
| HK1204547A1 (en) | 2015-11-27 |
| WO2013151584A1 (en) | 2013-10-10 |
| EP3815685A3 (en) | 2021-10-13 |
| US10555936B2 (en) | 2020-02-11 |
| AU2012376221A1 (en) | 2014-06-19 |
| CN104136026A (zh) | 2014-11-05 |
| JP6118808B2 (ja) | 2017-04-19 |
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