CA2876703A1 - Oxabicycloheptanes and oxabicycloheptenes for the treatment of reperfusion injury - Google Patents
Oxabicycloheptanes and oxabicycloheptenes for the treatment of reperfusion injury Download PDFInfo
- Publication number
- CA2876703A1 CA2876703A1 CA2876703A CA2876703A CA2876703A1 CA 2876703 A1 CA2876703 A1 CA 2876703A1 CA 2876703 A CA2876703 A CA 2876703A CA 2876703 A CA2876703 A CA 2876703A CA 2876703 A1 CA2876703 A1 CA 2876703A1
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- alkyl
- alkenyl
- substituted
- alkynyl
- aryl
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US201261666535P | 2012-06-29 | 2012-06-29 | |
| US61/666,535 | 2012-06-29 | ||
| US201361782894P | 2013-03-14 | 2013-03-14 | |
| US61/782,894 | 2013-03-14 | ||
| PCT/US2013/048697 WO2014005080A1 (en) | 2012-06-29 | 2013-06-28 | Oxabicycloheptanes and oxabicycloheptenes for the treatment of reperfusion injury |
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| CA2876703A1 true CA2876703A1 (en) | 2014-01-03 |
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| CA2876703A Abandoned CA2876703A1 (en) | 2012-06-29 | 2013-06-28 | Oxabicycloheptanes and oxabicycloheptenes for the treatment of reperfusion injury |
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| CA (1) | CA2876703A1 (enExample) |
| WO (1) | WO2014005080A1 (enExample) |
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| WO2010147612A1 (en) | 2009-06-18 | 2010-12-23 | Lixte Biotechnology, Inc. | Methods of modulating cell regulation by inhibiting p53 |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| US10149847B2 (en) | 2012-06-29 | 2018-12-11 | Lixte Biotechnology, Inc. | Oxabicycloheptanes and oxabicycloheptenes for the treatment of diabetes |
| MX2015014249A (es) * | 2013-04-09 | 2016-06-02 | Lixte Biotechnology Inc | Formulaciones de oxabicicloheptanos y oxabicicloheptenos. |
| BR112016025659B1 (pt) | 2014-05-13 | 2023-03-07 | Novartis Ag | Indutores de condrogênese, seu uso, e composição farmacêutica |
| US20170209434A1 (en) | 2014-07-24 | 2017-07-27 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Protein phosphatase 2a inhibitors for treating myelodysplastic syndromes |
| CA2960989A1 (en) * | 2014-09-12 | 2016-03-17 | Lixte Biotechnology, Inc. | Human dosing of phosphatase inhibitor |
| AU2016219853B2 (en) | 2015-02-19 | 2019-05-16 | Lixte Biotechnology, Inc. | Oxabicycloheptanes and oxabicycloheptenes for the treatment of depressive and stress disorders |
| HUE050177T2 (hu) * | 2015-05-15 | 2020-11-30 | Lixte Biotechnology Inc | Oxabicikloheptán elõvegyületek |
| CA3046515A1 (en) | 2016-12-08 | 2018-06-14 | Lixte Biotechnology, Inc. | Oxabicycloheptanes for modulation of immune response |
| US12440479B2 (en) | 2018-03-28 | 2025-10-14 | Georg-August-Universitaet Goettingen, Stiftung Oeffentlichen Rechts, Universitaetsmedizin | Prevention or treatment of chronic organ injury |
| CN118791500B (zh) * | 2024-06-17 | 2025-11-21 | 中国药科大学 | 7-氧杂双环[2.2.1]庚烷-2,3-二羧酸类衍生物及其制备方法和应用 |
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| US4931460A (en) * | 1987-09-17 | 1990-06-05 | E. R. Squibb & Sons, Inc. | Post-ischemic myocardial dysfunction using thromboxane A2 antagonists |
| WO1998014606A1 (en) * | 1996-10-04 | 1998-04-09 | South Alabama Medical Science Foundation | Method for diminishing myocardial infarction using protein phosphatase inhibitors |
| MX2009008347A (es) | 2007-02-06 | 2009-10-19 | Lixte Biotechnology Holdings I | Oxabicicloheptanos y oxabicicloheptenos, su preparacion y uso. |
| US8058268B2 (en) | 2008-08-01 | 2011-11-15 | Lixte Biotechnology, Inc. | Neuroprotective agents for the prevention and treatment of neurodegenerative diseases |
| EP2309853A4 (en) * | 2008-08-01 | 2012-04-25 | Lixte Biotechnology Inc | METHOD FOR CELL MITITULATING BY INHIBITION OF SERIN / THREONINE PHOSPHATASE |
| MX2015014249A (es) * | 2013-04-09 | 2016-06-02 | Lixte Biotechnology Inc | Formulaciones de oxabicicloheptanos y oxabicicloheptenos. |
| CA2960989A1 (en) * | 2014-09-12 | 2016-03-17 | Lixte Biotechnology, Inc. | Human dosing of phosphatase inhibitor |
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2013
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2017
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Also Published As
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| JP6262225B2 (ja) | 2018-01-17 |
| EP2870161B1 (en) | 2018-08-08 |
| JP2018048178A (ja) | 2018-03-29 |
| HK1209424A1 (en) | 2016-04-01 |
| WO2014005080A1 (en) | 2014-01-03 |
| US20150174123A1 (en) | 2015-06-25 |
| JP2015522032A (ja) | 2015-08-03 |
| CN104619710B (zh) | 2017-09-22 |
| CN104619710A (zh) | 2015-05-13 |
| EP2870161A4 (en) | 2015-12-23 |
| EP2870161A1 (en) | 2015-05-13 |
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Effective date: 20190628 |