CA2870198C - Process for purifying recombinant plasmodium falciparum circumsporozoite protein - Google Patents
Process for purifying recombinant plasmodium falciparum circumsporozoite protein Download PDFInfo
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- CA2870198C CA2870198C CA2870198A CA2870198A CA2870198C CA 2870198 C CA2870198 C CA 2870198C CA 2870198 A CA2870198 A CA 2870198A CA 2870198 A CA2870198 A CA 2870198A CA 2870198 C CA2870198 C CA 2870198C
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- rcsp
- days
- circumsporozoite protein
- falciparum circumsporozoite
- arginine
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Tropical Medicine & Parasitology (AREA)
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- Biophysics (AREA)
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- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
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| US201261641105P | 2012-05-01 | 2012-05-01 | |
| US61/641,105 | 2012-05-01 | ||
| US13/844,261 | 2013-03-15 | ||
| US13/844,261 US9169304B2 (en) | 2012-05-01 | 2013-03-15 | Process for purifying recombinant Plasmodium falciparum circumsporozoite protein |
| PCT/US2013/037656 WO2013165732A1 (en) | 2012-05-01 | 2013-04-22 | Process for purifying recombinant plasmodium falciparum circumsporozoite protein |
Publications (2)
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| CA2870198A1 CA2870198A1 (en) | 2013-11-07 |
| CA2870198C true CA2870198C (en) | 2019-12-03 |
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| CA2870198A Active CA2870198C (en) | 2012-05-01 | 2013-04-22 | Process for purifying recombinant plasmodium falciparum circumsporozoite protein |
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| WO (1) | WO2013165732A1 (cg-RX-API-DMAC7.html) |
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| US9169304B2 (en) | 2012-05-01 | 2015-10-27 | Pfenex Inc. | Process for purifying recombinant Plasmodium falciparum circumsporozoite protein |
| WO2015105551A1 (en) * | 2014-01-09 | 2015-07-16 | Kentucky Bioprocessing, Inc. | Method of purifying monoclonal antibodies |
| WO2015148943A1 (en) * | 2014-03-28 | 2015-10-01 | Conjugon, Inc. | Preparation of small colony variants of therapeutic bacteria |
| ES2952405T3 (es) | 2014-12-01 | 2023-10-31 | Pfenex Inc | Parejas de fusión para la producción de péptidos |
| CN109966319B (zh) * | 2017-12-22 | 2022-11-22 | 四川好医生攀西药业有限责任公司 | 一种康复新液的原料及其制备方法和应用 |
| CN108559721A (zh) * | 2018-05-15 | 2018-09-21 | 北京师范大学 | 一种净化空气的复合微生物菌剂及其应用 |
| EP4171630A1 (en) * | 2020-06-29 | 2023-05-03 | Path | Pre-erythrocytic malaria vaccines |
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| ES2639398T3 (es) | 2010-03-04 | 2017-10-26 | Pfenex Inc. | Método para producir proteína de interferón recombinante soluble sin desnaturalización |
| KR20130072201A (ko) | 2010-03-30 | 2013-07-01 | 피페넥스 인크. | 재조합 독소 단백질의 고수준 발현 |
| WO2011139718A1 (en) | 2010-05-03 | 2011-11-10 | Genentech, Inc. | Compositions and methods useful for reducing the viscosity of protein-containing formulations |
| DK2385107T3 (en) * | 2010-05-03 | 2016-12-12 | Pasteur Institut | Lentiviral vector-based immunological compounds against malaria |
| WO2012154199A1 (en) | 2010-10-18 | 2012-11-15 | The Government Of The United States, As Represented By The Secretary Of The Army | Soluble recombinant plasmodium falciparum circumsporozoite protein |
| US9169304B2 (en) | 2012-05-01 | 2015-10-27 | Pfenex Inc. | Process for purifying recombinant Plasmodium falciparum circumsporozoite protein |
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| EP2844666A4 (en) | 2015-11-04 |
| EP2844666B1 (en) | 2019-07-17 |
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| AU2013256757A1 (en) | 2014-10-30 |
| TW201348250A (zh) | 2013-12-01 |
| KR102087461B1 (ko) | 2020-03-10 |
| BR112014027019A2 (pt) | 2017-07-11 |
| CN104379596B (zh) | 2018-05-29 |
| BR112014027019B1 (pt) | 2022-09-06 |
| WO2013165732A1 (en) | 2013-11-07 |
| MY166380A (en) | 2018-06-25 |
| CA2870198A1 (en) | 2013-11-07 |
| US9169304B2 (en) | 2015-10-27 |
| CN104379596A (zh) | 2015-02-25 |
| US20140051841A1 (en) | 2014-02-20 |
| AR090900A1 (es) | 2014-12-17 |
| JP2015517464A (ja) | 2015-06-22 |
| AU2013256757B2 (en) | 2017-02-16 |
| MX2014013124A (es) | 2015-02-05 |
| ZA201407420B (en) | 2016-10-26 |
| US9849177B2 (en) | 2017-12-26 |
| NZ630121A (en) | 2016-06-24 |
| KR20150027743A (ko) | 2015-03-12 |
| SG11201407108TA (en) | 2014-11-27 |
| JP6238967B2 (ja) | 2017-11-29 |
| EP2844666A1 (en) | 2015-03-11 |
| TWI630213B (zh) | 2018-07-21 |
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