CA2868508A1 - Schweinfurthin analogues - Google Patents

Schweinfurthin analogues Download PDF

Info

Publication number
CA2868508A1
CA2868508A1 CA2868508A CA2868508A CA2868508A1 CA 2868508 A1 CA2868508 A1 CA 2868508A1 CA 2868508 A CA2868508 A CA 2868508A CA 2868508 A CA2868508 A CA 2868508A CA 2868508 A1 CA2868508 A1 CA 2868508A1
Authority
CA
Canada
Prior art keywords
compound
mmol
alkyl
et0ac
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2868508A
Other languages
English (en)
French (fr)
Inventor
John Kodet
Jeffrey D. Neighbors
David F. Wiemer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Iowa Research Foundation
Original Assignee
University of Iowa Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Iowa Research Foundation filed Critical University of Iowa Research Foundation
Publication of CA2868508A1 publication Critical patent/CA2868508A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA2868508A 2012-03-26 2013-03-25 Schweinfurthin analogues Abandoned CA2868508A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261615725P 2012-03-26 2012-03-26
US61/615,725 2012-03-26
PCT/US2013/033722 WO2013148584A1 (en) 2012-03-26 2013-03-25 Schweinfurthin analogues

Publications (1)

Publication Number Publication Date
CA2868508A1 true CA2868508A1 (en) 2013-10-03

Family

ID=49261149

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2868508A Abandoned CA2868508A1 (en) 2012-03-26 2013-03-25 Schweinfurthin analogues

Country Status (8)

Country Link
US (1) US9428493B2 (enExample)
EP (1) EP2831063B1 (enExample)
JP (1) JP2015512404A (enExample)
CN (1) CN104583203B (enExample)
AU (1) AU2013240007B2 (enExample)
CA (1) CA2868508A1 (enExample)
ES (1) ES2655027T3 (enExample)
WO (1) WO2013148584A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019218384B2 (en) * 2018-02-12 2025-09-04 The Penn State Research Foundation Methods and materials for treating cancer
CN108658949B (zh) * 2018-06-29 2021-05-25 云南大学 一种用作抗肿瘤药物的化合物及其生产方法
FR3124946B1 (fr) * 2021-07-06 2024-11-08 Centre Nat Rech Scient Nouveaux composés dérivés des schweinfurthines G, E, F

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US7358377B2 (en) 2004-03-29 2008-04-15 University Of Iowa Research Foundation Schweinfurthin analogues
WO2009158516A1 (en) 2008-06-27 2009-12-30 University Of Iowa Research Foundation Schweinfurthin analogues
WO2010127235A1 (en) * 2009-04-30 2010-11-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Schweinfurthins and uses thereof

Also Published As

Publication number Publication date
US9428493B2 (en) 2016-08-30
CN104583203A (zh) 2015-04-29
EP2831063A1 (en) 2015-02-04
JP2015512404A (ja) 2015-04-27
ES2655027T3 (es) 2018-02-16
EP2831063A4 (en) 2015-07-29
WO2013148584A1 (en) 2013-10-03
US20150045404A1 (en) 2015-02-12
CN104583203B (zh) 2017-06-13
AU2013240007B2 (en) 2017-06-29
EP2831063B1 (en) 2017-10-04
AU2013240007A1 (en) 2014-10-16
HK1206745A1 (en) 2016-01-15

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180320

FZDE Dead

Effective date: 20200831