CA2866854C - Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system - Google Patents
Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system Download PDFInfo
- Publication number
- CA2866854C CA2866854C CA2866854A CA2866854A CA2866854C CA 2866854 C CA2866854 C CA 2866854C CA 2866854 A CA2866854 A CA 2866854A CA 2866854 A CA2866854 A CA 2866854A CA 2866854 C CA2866854 C CA 2866854C
- Authority
- CA
- Canada
- Prior art keywords
- fluid
- well
- temperature
- housing
- temperature sensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 169
- 238000000034 method Methods 0.000 title claims abstract description 53
- 238000012545 processing Methods 0.000 title description 34
- 239000006101 laboratory sample Substances 0.000 title description 2
- 238000013019 agitation Methods 0.000 claims abstract description 39
- 230000033001 locomotion Effects 0.000 claims abstract description 30
- 238000004891 communication Methods 0.000 claims abstract description 17
- 239000000523 sample Substances 0.000 claims description 75
- 238000010438 heat treatment Methods 0.000 claims description 15
- 239000010408 film Substances 0.000 claims description 2
- 239000011888 foil Substances 0.000 claims description 2
- 230000000737 periodic effect Effects 0.000 claims description 2
- 239000010409 thin film Substances 0.000 claims description 2
- 230000000295 complement effect Effects 0.000 claims 1
- 230000008569 process Effects 0.000 abstract description 35
- 238000006243 chemical reaction Methods 0.000 description 12
- 238000001816 cooling Methods 0.000 description 10
- 239000000463 material Substances 0.000 description 10
- 238000012546 transfer Methods 0.000 description 10
- 239000003153 chemical reaction reagent Substances 0.000 description 9
- 239000013529 heat transfer fluid Substances 0.000 description 5
- 229910052751 metal Inorganic materials 0.000 description 5
- 239000002184 metal Substances 0.000 description 5
- 229910052782 aluminium Inorganic materials 0.000 description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 4
- 238000009529 body temperature measurement Methods 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
- 229910045601 alloy Inorganic materials 0.000 description 3
- 239000000956 alloy Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000001276 controlling effect Effects 0.000 description 3
- 229910052802 copper Inorganic materials 0.000 description 3
- 239000010949 copper Substances 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 238000002509 fluorescent in situ hybridization Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 150000002739 metals Chemical class 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 238000005842 biochemical reaction Methods 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000011551 heat transfer agent Substances 0.000 description 2
- 238000007901 in situ hybridization Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229910052755 nonmetal Inorganic materials 0.000 description 2
- 150000002843 nonmetals Chemical class 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 239000011435 rock Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000000636 Northern blotting Methods 0.000 description 1
- 238000002105 Southern blotting Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 238000013075 data extraction Methods 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- -1 for example Substances 0.000 description 1
- 238000001502 gel electrophoresis Methods 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
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- 238000003364 immunohistochemistry Methods 0.000 description 1
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- 230000014759 maintenance of location Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
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- 239000010935 stainless steel Substances 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
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- 238000005406 washing Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/23—Mixing the contents of independent containers, e.g. test tubes by pivoting the containers about an axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2115—Temperature
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/22—Control or regulation
- B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
- B01F35/2215—Temperature
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D23/00—Control of temperature
- G05D23/19—Control of temperature characterised by the use of electric means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00138—Slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
- G01N2035/00386—Holding samples at elevated temperature (incubation) using fluid heat transfer medium
- G01N2035/00396—Holding samples at elevated temperature (incubation) using fluid heat transfer medium where the fluid is a liquid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00524—Mixing by agitating sample carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/112499—Automated chemical analysis with sample on test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/115831—Condition or time responsive
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Automation & Control Theory (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261608762P | 2012-03-09 | 2012-03-09 | |
| US61/608,762 | 2012-03-09 | ||
| PCT/US2013/029747 WO2013134583A1 (en) | 2012-03-09 | 2013-03-08 | Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2866854A1 CA2866854A1 (en) | 2013-09-12 |
| CA2866854C true CA2866854C (en) | 2020-08-18 |
Family
ID=49117367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2866854A Active CA2866854C (en) | 2012-03-09 | 2013-03-08 | Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9909962B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2823281B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6138173B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104272082B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2866854C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013134583A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6397674B2 (ja) * | 2014-07-18 | 2018-09-26 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| WO2016149666A1 (en) | 2015-03-19 | 2016-09-22 | Beckman Coulter, Inc. | Dispenser for an analyzer |
| AU2016271049B9 (en) | 2015-05-29 | 2019-07-18 | Illumina, Inc. | Sample carrier and assay system for conducting designated reactions |
| DE102016225885B4 (de) * | 2016-12-21 | 2023-12-21 | Prime23 GmbH | Vorrichtung und Verfahren zum Benetzen von biologischem Material |
| US12195717B2 (en) * | 2017-05-04 | 2025-01-14 | Universität Zürich | Cell culture device |
| CN110271691B (zh) * | 2019-07-05 | 2022-11-22 | 中国飞机强度研究所 | 飞机气候环境实验室温度校准布局结构、采集系统及方法 |
| DE102019215577B3 (de) * | 2019-10-10 | 2020-11-05 | Prime23 GmbH | Vorrichtung und Verfahren zur Benetzung von biologischem Material |
| AU2021281387A1 (en) * | 2020-05-27 | 2022-11-03 | Agilent Technologies, Inc. | Apparatus and method for processing biological samples |
| CN113134318B (zh) * | 2021-03-18 | 2023-02-03 | 上海品致测控技术有限公司 | 恒温摇床控制方法及控制器 |
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| EP0342155A3 (de) | 1988-05-13 | 1990-06-27 | Agrogen-Stiftung | Laboratoriumsgerät zum wahlweisen Heizen und Kühlen |
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-
2013
- 2013-03-08 CN CN201380023961.8A patent/CN104272082B/zh not_active Expired - Fee Related
- 2013-03-08 WO PCT/US2013/029747 patent/WO2013134583A1/en not_active Ceased
- 2013-03-08 EP EP13757350.7A patent/EP2823281B1/en not_active Not-in-force
- 2013-03-08 CA CA2866854A patent/CA2866854C/en active Active
- 2013-03-08 US US14/382,944 patent/US9909962B2/en active Active
- 2013-03-08 JP JP2014561131A patent/JP6138173B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013134583A1 (en) | 2013-09-12 |
| EP2823281A1 (en) | 2015-01-14 |
| US9909962B2 (en) | 2018-03-06 |
| EP2823281B1 (en) | 2018-11-28 |
| JP6138173B2 (ja) | 2017-05-31 |
| CN104272082A (zh) | 2015-01-07 |
| CA2866854A1 (en) | 2013-09-12 |
| US20150044664A1 (en) | 2015-02-12 |
| JP2015509610A (ja) | 2015-03-30 |
| CN104272082B (zh) | 2017-02-22 |
| EP2823281A4 (en) | 2015-07-01 |
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Effective date: 20180223 |