CA2866230C - Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections - Google Patents
Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections Download PDFInfo
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- CA2866230C CA2866230C CA2866230A CA2866230A CA2866230C CA 2866230 C CA2866230 C CA 2866230C CA 2866230 A CA2866230 A CA 2866230A CA 2866230 A CA2866230 A CA 2866230A CA 2866230 C CA2866230 C CA 2866230C
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- poly
- starch
- microparticle
- alginate
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
Landscapes
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- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Biotechnology (AREA)
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- Oncology (AREA)
- Otolaryngology (AREA)
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- Plant Pathology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP12166595.4 | 2012-05-03 | ||
| EP12166595 | 2012-05-03 | ||
| PCT/EP2013/059079 WO2013164380A1 (en) | 2012-05-03 | 2013-05-02 | Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
Publications (2)
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| CA2866230A1 CA2866230A1 (en) | 2013-11-07 |
| CA2866230C true CA2866230C (en) | 2020-08-18 |
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| CN (1) | CN104394846B (OSRAM) |
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| SG (2) | SG11201406208QA (OSRAM) |
| WO (1) | WO2013164380A1 (OSRAM) |
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| JP6349304B2 (ja) | 2012-05-03 | 2018-06-27 | ヤンセン・サイエンシズ・アイルランド・ユーシー | 上気道感染症の処置のためのポリイノシン−ポリシチジル酸（ポリ（ｉ：ｃ））製剤 |
| CA2929142A1 (en) * | 2013-11-06 | 2015-05-14 | Janssen Sciences Ireland Uc | Polylnosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
| GB201415381D0 (en) * | 2014-08-29 | 2014-10-15 | Algipharma As | Inhalable powder formulations of alginate oligomers |
| KR20180004233A (ko) * | 2015-05-11 | 2018-01-10 | 얀센 사이언시즈 아일랜드 유씨 | 상기도 감염의 예방 및/또는 치료를 위한 폴리이노신-폴리사이티딜산 (Poly (I:C)) 완두 전분 제형 |
| ES2715251B1 (es) | 2015-11-17 | 2020-09-07 | Bioncotech Therapeutics S L | Novedosa composicion farmaceutica que comprende particulas que comprenden un complejo de un polirribonucleotido de doble cadena y una polialquilenimina |
| AU2016365219A1 (en) * | 2015-11-30 | 2018-07-05 | Novus Therapeutics, Inc. | Compositions and methods for otologic prophylaxis and treatment |
| US20200060972A1 (en) | 2016-11-16 | 2020-02-27 | Janssen Sciences Ireland Unlimited Company | Formulations of polyinosinic acid and polycytidylic acid for the prevention of upper respiratory tract infections |
| US10849921B2 (en) | 2017-05-17 | 2020-12-01 | Bioncotech Therapeutics Sl | Pharmaceutical composition comprising particles comprising a complex of a double-stranded polyribonucleotide and a polyalkyleneimine |
| US12226477B2 (en) * | 2018-06-29 | 2025-02-18 | Beijing Yisheng Biotechnology Co., Ltd. | Methods for preparing complex for enhancing immune response |
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| GB8723846D0 (en) | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
| US5707644A (en) * | 1989-11-04 | 1998-01-13 | Danbiosyst Uk Limited | Small particle compositions for intranasal drug delivery |
| CA2079509C (en) | 1991-10-01 | 2002-05-14 | Shigeyuki Takada | Prolonged release microparticle preparation and production of the same |
| GB9606188D0 (en) * | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
| AR012448A1 (es) | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
| CA2203843C (en) | 1997-04-28 | 2013-07-23 | Her Majesty The Queen, In Right Of Canada, As Represented By The Ministe R Of National Defence | Liposome-encapsulated poly iclc |
| MA25590A1 (fr) * | 1998-09-14 | 2002-12-31 | Inhale Therapeutic Syst | Agent actif de delivraison de poudre seche |
| CA2424892A1 (en) * | 2000-10-06 | 2002-04-11 | Jagotec Ag | Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight |
| US20040248837A1 (en) * | 2002-11-01 | 2004-12-09 | Eyal Raz | Methods of treating pulmonary fibrotic disorders |
| WO2004073729A1 (ja) | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | 薬物の経鼻投与用組成物 |
| CN1867355A (zh) | 2003-08-11 | 2006-11-22 | 财团法人阪大微生物病研究会 | 包含诱导粘膜免疫的佐剂的新型疫苗 |
| AU2004314706A1 (en) * | 2003-12-11 | 2005-08-11 | University Of Miami | Immunotherapy compositions, method of making and method of use thereof |
| CN101229378A (zh) | 2005-05-05 | 2008-07-30 | 国家淀粉及化学投资控股公司 | 用于送递活性剂的组合物 |
| ATE539767T1 (de) | 2005-06-08 | 2012-01-15 | Yisheng Biopharma Singapore Pte Ltd | Adjuvans auf basis von polyinosinsäure/polycytidylsäure |
| US20070166239A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Mucosal immunogenic substances comprising a polyinosinic acid - polycytidilic acid based adjuvant |
| GB0607534D0 (en) | 2006-04-13 | 2006-05-24 | Univ London Pharmacy | Colonic drug delivery formulation |
| EP2046740B1 (en) | 2006-07-22 | 2012-05-23 | Oxagen Limited | Compounds having crth2 antagonist activity |
| CL2007002218A1 (es) | 2006-08-03 | 2008-03-14 | Celgene Corp Soc Organizada Ba | Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa. |
| AR067997A1 (es) * | 2007-08-24 | 2009-10-28 | Novartis Ag | Compuestos organicos |
| JP2009209086A (ja) * | 2008-03-04 | 2009-09-17 | Masami Moriyama | 粘膜投与型ワクチン |
| UA90013C2 (ru) * | 2008-03-19 | 2010-03-25 | Давид Анатолійович Нога | Фармацевтическая композиция, содержащая инсулин, и способ его получения |
| EP2116602A1 (en) | 2008-05-07 | 2009-11-11 | Institut Gustave Roussy | Combination products for treating cancer |
| CN102281870B (zh) * | 2008-12-10 | 2015-03-04 | 安徽中人科技有限责任公司 | 新型控释组合物 |
| CN101491503A (zh) | 2008-12-17 | 2009-07-29 | 天津瑞普生物技术股份有限公司 | 一种用于宠物的聚肌胞滴丸及其制备方法 |
| SI3098239T1 (sl) | 2008-12-22 | 2020-03-31 | Targimmune Therapeutics Ag | Egfr-homing vektor dvoverižne rna za sistemsko zdravljenje raka |
| CN101757018A (zh) * | 2008-12-24 | 2010-06-30 | 天津瑞普生物技术股份有限公司 | 一种用于畜禽的聚肌胞干粉及其制备方法 |
| AU2010232180B2 (en) | 2009-03-31 | 2016-09-22 | Japan As Represented By The Director-General Of National Institute Of Infectious Diseases | Method for prophylaxis of influenza using vaccine for intranasal administration |
| EP2598145A1 (en) | 2010-07-28 | 2013-06-05 | Boehringer Ingelheim International GmbH | Pharmaceutical composition for treatment of respiratory and inflammatory diseases |
| US8431155B1 (en) | 2012-04-30 | 2013-04-30 | Veroscience Llc | Bromocriptine formulations |
| JP6349304B2 (ja) | 2012-05-03 | 2018-06-27 | ヤンセン・サイエンシズ・アイルランド・ユーシー | 上気道感染症の処置のためのポリイノシン−ポリシチジル酸（ポリ（ｉ：ｃ））製剤 |
| CA2929142A1 (en) | 2013-11-06 | 2015-05-14 | Janssen Sciences Ireland Uc | Polylnosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
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| AU2013255885A1 (en) | 2014-09-25 |
| AU2013255885C1 (en) | 2018-04-26 |
| MX2014013256A (es) | 2015-01-16 |
| KR20150008855A (ko) | 2015-01-23 |
| JP6349304B2 (ja) | 2018-06-27 |
| CN104394846A (zh) | 2015-03-04 |
| CN104394846B (zh) | 2018-10-19 |
| JP2015515968A (ja) | 2015-06-04 |
| CO7101247A2 (es) | 2014-10-31 |
| NZ630040A (en) | 2016-10-28 |
| WO2013164380A1 (en) | 2013-11-07 |
| US20150140042A1 (en) | 2015-05-21 |
| SG11201406208QA (en) | 2014-11-27 |
| BR112014026957A2 (pt) | 2017-06-27 |
| US9682096B2 (en) | 2017-06-20 |
| KR102240042B1 (ko) | 2021-04-14 |
| CL2014002929A1 (es) | 2015-01-16 |
| US9987300B2 (en) | 2018-06-05 |
| EP2846767B1 (en) | 2022-01-26 |
| SG10201607288VA (en) | 2016-10-28 |
| EP2846767A1 (en) | 2015-03-18 |
| US20160296551A1 (en) | 2016-10-13 |
| RU2014148544A (ru) | 2016-06-27 |
| RU2650636C2 (ru) | 2018-04-16 |
| HK1203390A1 (en) | 2015-10-30 |
| BR112014026957A8 (pt) | 2018-01-16 |
| US10485816B2 (en) | 2019-11-26 |
| IN2014MN02359A (OSRAM) | 2015-08-14 |
| ES2911116T3 (es) | 2022-05-17 |
| AU2013255885B2 (en) | 2017-10-05 |
| CA2866230A1 (en) | 2013-11-07 |
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