CA2864865A1 - Side-chain protected oligopeptide fragment condensation using subtilisins in organic solvents - Google Patents
Side-chain protected oligopeptide fragment condensation using subtilisins in organic solvents Download PDFInfo
- Publication number
- CA2864865A1 CA2864865A1 CA2864865A CA2864865A CA2864865A1 CA 2864865 A1 CA2864865 A1 CA 2864865A1 CA 2864865 A CA2864865 A CA 2864865A CA 2864865 A CA2864865 A CA 2864865A CA 2864865 A1 CA2864865 A1 CA 2864865A1
- Authority
- CA
- Canada
- Prior art keywords
- oligopeptide
- protected
- amino acid
- terminal
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12157571.6 | 2012-02-29 | ||
| EP12157571.6A EP2634193B1 (en) | 2012-02-29 | 2012-02-29 | Side-chain protected oligopeptide fragment condensation using subtilisins in organic solvents |
| PCT/NL2013/050125 WO2013129926A1 (en) | 2012-02-29 | 2013-02-28 | Side-chain protected oligopeptide fragment condensation using subtilisins in organic solvents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2864865A1 true CA2864865A1 (en) | 2013-09-06 |
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ID=47884473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2864865A Abandoned CA2864865A1 (en) | 2012-02-29 | 2013-02-28 | Side-chain protected oligopeptide fragment condensation using subtilisins in organic solvents |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9598714B2 (en:Method) |
| EP (1) | EP2634193B1 (en:Method) |
| JP (1) | JP2015508666A (en:Method) |
| CN (1) | CN104284901A (en:Method) |
| CA (1) | CA2864865A1 (en:Method) |
| DK (1) | DK2634193T3 (en:Method) |
| ES (1) | ES2531054T3 (en:Method) |
| IN (1) | IN2014MN01770A (en:Method) |
| WO (1) | WO2013129926A1 (en:Method) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2657250T3 (pl) * | 2010-12-21 | 2018-02-28 | Cj Cheiljedang Corporation | Odmiana polipeptydu posiadającego aktywność acetylotransferazy homoseryny oraz mikroorganizm wyrażający to samo |
| JP7017409B2 (ja) | 2014-10-10 | 2022-02-08 | エンザイペプ ビー．ブイ． | 加水分解に対する合成の比が改善したスブチリシン変異体を使用するペプチド断片縮合及び環化 |
| WO2017007324A1 (en) * | 2015-07-09 | 2017-01-12 | Enzypep B.V. | Designing an enzymatic peptide fragment condensation strategy |
| US10827880B2 (en) | 2016-02-03 | 2020-11-10 | Conair Corporation | Food processor and modular lid assembly therefor |
| ES3038393T3 (en) | 2018-08-09 | 2025-10-13 | Hoffmann La Roche | Cleavable linker for peptide synthesis |
| US20250043240A1 (en) * | 2021-11-12 | 2025-02-06 | Virginia Tech Intellectual Properties, Inc. | Hydrolyzed protein serum replacement compositions |
| KR102874008B1 (ko) * | 2022-03-11 | 2025-10-21 | 강성구 | 고상 유기 합성용 기재 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6509727A (en:Method) * | 1965-07-28 | 1967-01-30 | ||
| US5316935A (en) | 1992-04-06 | 1994-05-31 | California Institute Of Technology | Subtilisin variants suitable for hydrolysis and synthesis in organic media |
| ATE440117T1 (de) * | 2005-04-01 | 2009-09-15 | Intezyne Technologies Inc | Polymermicellen für die arzneistoffzufuhr |
| CN102216324B (zh) * | 2008-11-19 | 2014-02-12 | 帝斯曼知识产权资产管理有限公司 | 使用酶促反应和偶联反应的肽合成 |
-
2012
- 2012-02-29 ES ES12157571T patent/ES2531054T3/es active Active
- 2012-02-29 EP EP12157571.6A patent/EP2634193B1/en not_active Not-in-force
- 2012-02-29 DK DK12157571T patent/DK2634193T3/en active
-
2013
- 2013-02-28 IN IN1770MUN2014 patent/IN2014MN01770A/en unknown
- 2013-02-28 CA CA2864865A patent/CA2864865A1/en not_active Abandoned
- 2013-02-28 US US14/379,789 patent/US9598714B2/en active Active
- 2013-02-28 CN CN201380022510.2A patent/CN104284901A/zh active Pending
- 2013-02-28 WO PCT/NL2013/050125 patent/WO2013129926A1/en not_active Ceased
- 2013-02-28 JP JP2014559858A patent/JP2015508666A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014MN01770A (en:Method) | 2015-07-03 |
| DK2634193T3 (en) | 2015-03-02 |
| EP2634193A1 (en) | 2013-09-04 |
| WO2013129926A1 (en) | 2013-09-06 |
| US9598714B2 (en) | 2017-03-21 |
| US20150037840A1 (en) | 2015-02-05 |
| EP2634193B1 (en) | 2015-01-14 |
| JP2015508666A (ja) | 2015-03-23 |
| CN104284901A (zh) | 2015-01-14 |
| ES2531054T3 (es) | 2015-03-10 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20170228 |