CA2849752C - Method for producing polypeptide fragment with high efficiency, which is suitable for ncl method - Google Patents

Method for producing polypeptide fragment with high efficiency, which is suitable for ncl method Download PDF

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Publication number
CA2849752C
CA2849752C CA2849752A CA2849752A CA2849752C CA 2849752 C CA2849752 C CA 2849752C CA 2849752 A CA2849752 A CA 2849752A CA 2849752 A CA2849752 A CA 2849752A CA 2849752 C CA2849752 C CA 2849752C
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CA
Canada
Prior art keywords
polypeptide fragment
terminal
polypeptide
group
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
CA2849752A
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English (en)
French (fr)
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CA2849752A1 (en
Inventor
Yasuhiro Kajihara
Ryo Okamoto
Motoharu KIMURA
Kazuyuki ISHII
Original Assignee
Glytech Inc
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Application filed by Glytech Inc filed Critical Glytech Inc
Publication of CA2849752A1 publication Critical patent/CA2849752A1/en
Application granted granted Critical
Publication of CA2849752C publication Critical patent/CA2849752C/en
Active legal-status Critical Current
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5437IL-13
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA2849752A 2011-09-26 2012-09-21 Method for producing polypeptide fragment with high efficiency, which is suitable for ncl method Active CA2849752C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011-210007 2011-09-26
JP2011210007 2011-09-26
PCT/JP2012/074239 WO2013047372A1 (ja) 2011-09-26 2012-09-21 Ncl法に適した、ポリペプチド断片の効率的な製造方法

Publications (2)

Publication Number Publication Date
CA2849752A1 CA2849752A1 (en) 2013-04-04
CA2849752C true CA2849752C (en) 2020-06-23

Family

ID=47995404

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2849752A Active CA2849752C (en) 2011-09-26 2012-09-21 Method for producing polypeptide fragment with high efficiency, which is suitable for ncl method

Country Status (13)

Country Link
US (1) US20140377807A1 (https=)
EP (1) EP2762485B1 (https=)
JP (1) JP6186278B2 (https=)
KR (1) KR101942608B1 (https=)
CN (1) CN104080796A (https=)
AU (1) AU2012317742B2 (https=)
BR (1) BR112014007174B1 (https=)
CA (1) CA2849752C (https=)
IN (1) IN2014CN02854A (https=)
RU (1) RU2605411C2 (https=)
SG (2) SG11201400936QA (https=)
TW (1) TWI549963B (https=)
WO (1) WO2013047372A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3868401A1 (en) * 2020-02-21 2021-08-25 Assistance Publique Hôpitaux de Paris Optimization of peptide-melanin binding
JPWO2025009591A1 (https=) 2023-07-06 2025-01-09

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0832096T3 (da) 1995-05-04 2001-10-01 Scripps Research Inst Syntese af proteiner ved nativ kemisk ligering
US7943763B2 (en) 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
CA2533849C (en) 2003-07-28 2013-07-02 Otsuka Chemical Co., Ltd. Aminated complex-type sugar chain derivatives and process for the production thereof
JPWO2005095331A1 (ja) 2004-03-31 2008-02-21 塩野義製薬株式会社 糖鎖−ペプチド結合剤
JP2007114454A (ja) 2005-10-20 2007-05-10 Yamaha Corp マイクロレンズアレイとその製法
DK2000474T3 (en) 2006-03-29 2018-01-22 Glytech Inc PROCEDURE FOR PRODUCING A PEPTID THIOESTER COMPOUND
CN101583380B (zh) * 2006-11-30 2013-07-10 尼克塔治疗公司 用于制备聚合物轭合物的方法
JP2009242372A (ja) * 2008-03-11 2009-10-22 Yokohama City Univ 均一な糖鎖構造を有するエリスロポエチン誘導体
JP2010150730A (ja) 2008-12-25 2010-07-08 Soichiro Hayashi 中手指節関節運動制限具
TW201031749A (en) * 2009-02-10 2010-09-01 Otsuka Chemical Co Ltd IgG-Fc fragment and method for manufacturing the same
BRPI1016151B1 (pt) * 2009-06-26 2021-01-19 Glytech, Inc. processo para produção de um tioéster de peptídeo, processos para a produção de um polipeptídeo, processo para a produção de um segundo intermediário utilizado para o processo para a produção do tioéster de peptídeo e processo para a remoção de uma marca para a purificação adicionada a um lado terminal c de uma proteína recombinante

Also Published As

Publication number Publication date
KR101942608B1 (ko) 2019-01-25
KR20140091678A (ko) 2014-07-22
CN104080796A (zh) 2014-10-01
AU2012317742A1 (en) 2014-04-17
SG11201400936QA (en) 2014-10-30
JPWO2013047372A1 (ja) 2015-03-26
CA2849752A1 (en) 2013-04-04
RU2014115769A (ru) 2015-10-27
RU2605411C2 (ru) 2016-12-20
TWI549963B (zh) 2016-09-21
TW201321400A (zh) 2013-06-01
JP6186278B2 (ja) 2017-08-23
BR112014007174A2 (pt) 2017-04-04
BR112014007174B1 (pt) 2021-11-30
IN2014CN02854A (https=) 2015-07-03
US20140377807A1 (en) 2014-12-25
EP2762485A1 (en) 2014-08-06
EP2762485B1 (en) 2018-08-01
EP2762485A4 (en) 2015-06-24
AU2012317742B2 (en) 2016-10-13
WO2013047372A1 (ja) 2013-04-04
SG10201602024YA (en) 2016-04-28

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