BR112014007174B1 - Método para fabricar de maneira eficiente um primeiro fragmento de polipeptídeo adequado para o método ncl e método para a fabricação de um polipeptídeo glicosilado - Google Patents
Método para fabricar de maneira eficiente um primeiro fragmento de polipeptídeo adequado para o método ncl e método para a fabricação de um polipeptídeo glicosilado Download PDFInfo
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- BR112014007174B1 BR112014007174B1 BR112014007174-8A BR112014007174A BR112014007174B1 BR 112014007174 B1 BR112014007174 B1 BR 112014007174B1 BR 112014007174 A BR112014007174 A BR 112014007174A BR 112014007174 B1 BR112014007174 B1 BR 112014007174B1
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- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- NLIVDORGVGAOOJ-MAHBNPEESA-M xylene cyanol Chemical compound [Na+].C1=C(C)C(NCC)=CC=C1C(\C=1C(=CC(OS([O-])=O)=CC=1)OS([O-])=O)=C\1C=C(C)\C(=[NH+]/CC)\C=C/1 NLIVDORGVGAOOJ-MAHBNPEESA-M 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5437—IL-13
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011-210007 | 2011-09-26 | ||
| JP2011210007 | 2011-09-26 | ||
| PCT/JP2012/074239 WO2013047372A1 (ja) | 2011-09-26 | 2012-09-21 | Ｎｃｌ法に適した、ポリペプチド断片の効率的な製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014007174A2 BR112014007174A2 (pt) | 2017-04-04 |
| BR112014007174B1 true BR112014007174B1 (pt) | 2021-11-30 |
Family
ID=47995404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014007174-8A BR112014007174B1 (pt) | 2011-09-26 | 2012-09-21 | Método para fabricar de maneira eficiente um primeiro fragmento de polipeptídeo adequado para o método ncl e método para a fabricação de um polipeptídeo glicosilado |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140377807A1 (https=) |
| EP (1) | EP2762485B1 (https=) |
| JP (1) | JP6186278B2 (https=) |
| KR (1) | KR101942608B1 (https=) |
| CN (1) | CN104080796A (https=) |
| AU (1) | AU2012317742B2 (https=) |
| BR (1) | BR112014007174B1 (https=) |
| CA (1) | CA2849752C (https=) |
| IN (1) | IN2014CN02854A (https=) |
| RU (1) | RU2605411C2 (https=) |
| SG (2) | SG11201400936QA (https=) |
| TW (1) | TWI549963B (https=) |
| WO (1) | WO2013047372A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3868401A1 (en) * | 2020-02-21 | 2021-08-25 | Assistance Publique Hôpitaux de Paris | Optimization of peptide-melanin binding |
| JPWO2025009591A1 (https=) | 2023-07-06 | 2025-01-09 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0832096T3 (da) | 1995-05-04 | 2001-10-01 | Scripps Research Inst | Syntese af proteiner ved nativ kemisk ligering |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| CA2533849C (en) | 2003-07-28 | 2013-07-02 | Otsuka Chemical Co., Ltd. | Aminated complex-type sugar chain derivatives and process for the production thereof |
| JPWO2005095331A1 (ja) | 2004-03-31 | 2008-02-21 | 塩野義製薬株式会社 | 糖鎖−ペプチド結合剤 |
| JP2007114454A (ja) | 2005-10-20 | 2007-05-10 | Yamaha Corp | マイクロレンズアレイとその製法 |
| DK2000474T3 (en) | 2006-03-29 | 2018-01-22 | Glytech Inc | PROCEDURE FOR PRODUCING A PEPTID THIOESTER COMPOUND |
| CN101583380B (zh) * | 2006-11-30 | 2013-07-10 | 尼克塔治疗公司 | 用于制备聚合物轭合物的方法 |
| JP2009242372A (ja) * | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| JP2010150730A (ja) | 2008-12-25 | 2010-07-08 | Soichiro Hayashi | 中手指節関節運動制限具 |
| TW201031749A (en) * | 2009-02-10 | 2010-09-01 | Otsuka Chemical Co Ltd | IgG-Fc fragment and method for manufacturing the same |
| BRPI1016151B1 (pt) * | 2009-06-26 | 2021-01-19 | Glytech, Inc. | processo para produção de um tioéster de peptídeo, processos para a produção de um polipeptídeo, processo para a produção de um segundo intermediário utilizado para o processo para a produção do tioéster de peptídeo e processo para a remoção de uma marca para a purificação adicionada a um lado terminal c de uma proteína recombinante |
-
2012
- 2012-09-21 US US14/347,547 patent/US20140377807A1/en not_active Abandoned
- 2012-09-21 AU AU2012317742A patent/AU2012317742B2/en not_active Ceased
- 2012-09-21 SG SG11201400936QA patent/SG11201400936QA/en unknown
- 2012-09-21 RU RU2014115769/04A patent/RU2605411C2/ru active
- 2012-09-21 IN IN2854CHN2014 patent/IN2014CN02854A/en unknown
- 2012-09-21 KR KR1020147010021A patent/KR101942608B1/ko not_active Expired - Fee Related
- 2012-09-21 EP EP12837234.9A patent/EP2762485B1/en active Active
- 2012-09-21 WO PCT/JP2012/074239 patent/WO2013047372A1/ja not_active Ceased
- 2012-09-21 JP JP2013536233A patent/JP6186278B2/ja active Active
- 2012-09-21 BR BR112014007174-8A patent/BR112014007174B1/pt not_active IP Right Cessation
- 2012-09-21 CN CN201280057905.1A patent/CN104080796A/zh active Pending
- 2012-09-21 SG SG10201602024YA patent/SG10201602024YA/en unknown
- 2012-09-21 CA CA2849752A patent/CA2849752C/en active Active
- 2012-09-25 TW TW101135056A patent/TWI549963B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR101942608B1 (ko) | 2019-01-25 |
| KR20140091678A (ko) | 2014-07-22 |
| CN104080796A (zh) | 2014-10-01 |
| AU2012317742A1 (en) | 2014-04-17 |
| SG11201400936QA (en) | 2014-10-30 |
| CA2849752C (en) | 2020-06-23 |
| JPWO2013047372A1 (ja) | 2015-03-26 |
| CA2849752A1 (en) | 2013-04-04 |
| RU2014115769A (ru) | 2015-10-27 |
| RU2605411C2 (ru) | 2016-12-20 |
| TWI549963B (zh) | 2016-09-21 |
| TW201321400A (zh) | 2013-06-01 |
| JP6186278B2 (ja) | 2017-08-23 |
| BR112014007174A2 (pt) | 2017-04-04 |
| IN2014CN02854A (https=) | 2015-07-03 |
| US20140377807A1 (en) | 2014-12-25 |
| EP2762485A1 (en) | 2014-08-06 |
| EP2762485B1 (en) | 2018-08-01 |
| EP2762485A4 (en) | 2015-06-24 |
| AU2012317742B2 (en) | 2016-10-13 |
| WO2013047372A1 (ja) | 2013-04-04 |
| SG10201602024YA (en) | 2016-04-28 |
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