CA2846347C - Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals - Google Patents

Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals Download PDF

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Publication number
CA2846347C
CA2846347C CA2846347A CA2846347A CA2846347C CA 2846347 C CA2846347 C CA 2846347C CA 2846347 A CA2846347 A CA 2846347A CA 2846347 A CA2846347 A CA 2846347A CA 2846347 C CA2846347 C CA 2846347C
Authority
CA
Canada
Prior art keywords
alkyl
group
chroman
formula
yloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2846347A
Other languages
English (en)
French (fr)
Other versions
CA2846347A1 (en
Inventor
Werngard Czechtizky
John Weston
Nils Rackelmann
Michael Podeschwa
Petra Arndt
Klaus Wirth
Heinz Goegelein
Olaf Ritzeler
Volker Kraft
Patrice Bellevergue
Gary Mccort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of CA2846347A1 publication Critical patent/CA2846347A1/en
Application granted granted Critical
Publication of CA2846347C publication Critical patent/CA2846347C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2846347A 2011-09-12 2011-09-12 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals Expired - Fee Related CA2846347C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/065712 WO2013037388A1 (en) 2011-09-12 2011-09-12 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals

Publications (2)

Publication Number Publication Date
CA2846347A1 CA2846347A1 (en) 2013-03-21
CA2846347C true CA2846347C (en) 2019-05-21

Family

ID=44645708

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2846347A Expired - Fee Related CA2846347C (en) 2011-09-12 2011-09-12 Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals

Country Status (8)

Country Link
KR (1) KR101817925B1 (ko)
AU (1) AU2011376746B2 (ko)
CA (1) CA2846347C (ko)
IL (1) IL231096A (ko)
MA (1) MA35814B1 (ko)
SG (1) SG11201400518RA (ko)
WO (1) WO2013037388A1 (ko)
ZA (1) ZA201401335B (ko)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168380A (en) 1978-04-21 1979-09-18 Hoffmann-La Roche Inc. 7-Methoxy-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid
JPH0967336A (ja) 1995-09-04 1997-03-11 Kanebo Ltd 新規なイソチオウレア誘導体
ES2191284T3 (es) 1997-03-27 2003-09-01 Taisho Pharmaceutical Co Ltd Derivados de 2-fenoxianilina.
BR0013899A (pt) 1999-09-10 2003-07-08 Merck & Co Inc Composto, composição farmacêutica, processos de tratamento ou prevenção de câncer, de uma doença em que a angiogênese esteja implicada, da vascularização retinal, da retinopatia diabética, da degeneração macular relacionada a idade, de doenças inflamatórias, de uma doença ou condições dependentes da tirosina quinase, de patologias associadas com ossos, e, processos para produzir uma composição farmacêutica, e de reduzir ou prevenir dano tecidual em seguida a um evento isquêmico cerebral
WO2002032883A1 (fr) 2000-10-18 2002-04-25 Senju Pharmaceutical Co., Ltd. Nouveau derive de 4-benzyloxyphenyle et utilisation de ce derive
FI20011507A0 (fi) 2001-07-10 2001-07-10 Orion Corp Uusia yhdisteitä
AU2003244181A1 (en) 2002-06-25 2004-01-06 Yamanouchi Pharmaceutical Co., Ltd. Phenoxypyridine derivative or salt thereof
FI20030030A0 (fi) 2003-01-09 2003-01-09 Orion Corp Uusia yhdisteitä
JP5092111B2 (ja) 2007-02-05 2012-12-05 トーアエイヨー株式会社 ブトキシアニリン誘導体
EP2103939A1 (en) 2008-03-20 2009-09-23 sanofi-aventis Fluorescence based assay to detect sodium/calcium exchanger (NCX) "reverse mode" modulating compounds
US8354454B2 (en) 2008-10-01 2013-01-15 Merck Sharp & Dohme Corp. Prodrugs of oxazolidinone CETP inhibitors

Also Published As

Publication number Publication date
CA2846347A1 (en) 2013-03-21
SG11201400518RA (en) 2014-04-28
WO2013037388A1 (en) 2013-03-21
MA35814B1 (fr) 2014-12-01
ZA201401335B (en) 2015-08-26
IL231096A (en) 2017-07-31
IL231096A0 (en) 2014-03-31
AU2011376746B2 (en) 2017-06-15
KR101817925B1 (ko) 2018-01-12
KR20140063807A (ko) 2014-05-27
AU2011376746A1 (en) 2014-03-20

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EEER Examination request

Effective date: 20160907

MKLA Lapsed

Effective date: 20210913