CA2844742A1 - Kinase inhibitor polymorphs - Google Patents
Kinase inhibitor polymorphs Download PDFInfo
- Publication number
- CA2844742A1 CA2844742A1 CA2844742A CA2844742A CA2844742A1 CA 2844742 A1 CA2844742 A1 CA 2844742A1 CA 2844742 A CA2844742 A CA 2844742A CA 2844742 A CA2844742 A CA 2844742A CA 2844742 A1 CA2844742 A1 CA 2844742A1
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Classifications
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
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- Neurosurgery (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161522624P | 2011-08-11 | 2011-08-11 | |
| US61/522,624 | 2011-08-11 | ||
| PCT/US2012/050453 WO2013023184A1 (en) | 2011-08-11 | 2012-08-10 | Kinase inhibitor polymorphs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2844742A1 true CA2844742A1 (en) | 2013-02-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2844742A Abandoned CA2844742A1 (en) | 2011-08-11 | 2012-08-10 | Kinase inhibitor polymorphs |
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| US (1) | US20150065524A1 (OSRAM) |
| EP (1) | EP2741749A4 (OSRAM) |
| JP (1) | JP2014521726A (OSRAM) |
| KR (1) | KR20140079368A (OSRAM) |
| CN (1) | CN103957918A (OSRAM) |
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| BR (1) | BR112014003214A2 (OSRAM) |
| CA (1) | CA2844742A1 (OSRAM) |
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| CR (1) | CR20140082A (OSRAM) |
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| EA (1) | EA027970B1 (OSRAM) |
| EC (1) | ECSP14013236A (OSRAM) |
| HK (1) | HK1199203A1 (OSRAM) |
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| MX (1) | MX2014001662A (OSRAM) |
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| PE (1) | PE20141358A1 (OSRAM) |
| PH (1) | PH12014500331A1 (OSRAM) |
| RU (1) | RU2636588C2 (OSRAM) |
| SG (2) | SG2014009492A (OSRAM) |
| TN (1) | TN2014000063A1 (OSRAM) |
| WO (1) | WO2013023184A1 (OSRAM) |
| ZA (1) | ZA201401211B (OSRAM) |
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| DK1583562T3 (da) | 2003-01-06 | 2011-09-19 | Angiochem Inc | Angiopep-1, beslægtede forbindelser og anvendelser deraf |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| RU2531591C2 (ru) | 2008-10-15 | 2014-10-20 | Ангиокем Инк. | Конъюгаты этопозида и доксорубицина для доставки лекарственных средств |
| RU2011118056A (ru) | 2008-10-15 | 2012-11-27 | Ангиокем Инк. | Конъюгаты агонистов glp-1 и их применение |
| CN102307904A (zh) | 2008-12-05 | 2012-01-04 | 安吉奥开米公司 | 神经降压素或神经降压素类似物的缀合物及其用途 |
| AU2009327267A1 (en) | 2008-12-17 | 2011-07-14 | Angiochem, Inc. | Membrane type-1 matrix metalloprotein inhibitors and uses thereof |
| CA2759129C (en) | 2009-04-20 | 2018-12-11 | Angiochem Inc. | Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog |
| US9161988B2 (en) | 2009-07-02 | 2015-10-20 | Angiochem Inc. | Multimeric peptide conjugates and uses thereof |
| EP2776441A4 (en) * | 2011-11-08 | 2015-04-08 | Intellikine Llc | TREATMENT METHOD WITH MULTIPLE PHARMACEUTICAL AGENTS |
| CN104250250A (zh) * | 2013-06-25 | 2014-12-31 | 苏州科捷生物医药有限公司 | 4-芳香胺基嘧啶类化合物及其抗肿瘤用途 |
| CA2929181A1 (en) | 2013-11-13 | 2015-05-21 | Novartis Ag | Mtor inhibitors for enhancing the immune response |
| EP4026909A1 (en) | 2013-12-19 | 2022-07-13 | Novartis AG | Human mesothelin chimeric antigen receptors and uses thereof |
| EP3087101B1 (en) | 2013-12-20 | 2024-06-05 | Novartis AG | Regulatable chimeric antigen receptor |
| EP3593812A3 (en) | 2014-03-15 | 2020-05-27 | Novartis AG | Treatment of cancer using chimeric antigen receptor |
| SI3888674T1 (sl) | 2014-04-07 | 2024-08-30 | Novartis Ag | Zdravljenje raka z uporabo antigenskega himernega receptorja proti-CD19 |
| EP3193915A1 (en) | 2014-07-21 | 2017-07-26 | Novartis AG | Combinations of low, immune enhancing. doses of mtor inhibitors and cars |
| US11542488B2 (en) | 2014-07-21 | 2023-01-03 | Novartis Ag | Sortase synthesized chimeric antigen receptors |
| JP6831777B2 (ja) | 2014-07-21 | 2021-02-17 | ノバルティス アーゲー | Ｃｄ３３キメラ抗原受容体を使用する癌の処置 |
| WO2016019300A1 (en) | 2014-07-31 | 2016-02-04 | Novartis Ag | Subset-optimized chimeric antigen receptor-containing t-cells |
| AU2015301460B2 (en) | 2014-08-14 | 2021-04-08 | Novartis Ag | Treatment of cancer using GFR alpha-4 chimeric antigen receptor |
| WO2016028896A1 (en) | 2014-08-19 | 2016-02-25 | Novartis Ag | Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment |
| US10577417B2 (en) | 2014-09-17 | 2020-03-03 | Novartis Ag | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| WO2016057705A1 (en) | 2014-10-08 | 2016-04-14 | Novartis Ag | Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof |
| US20180140602A1 (en) | 2015-04-07 | 2018-05-24 | Novartis Ag | Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives |
| CN108473957B (zh) | 2015-04-17 | 2024-07-16 | 诺华股份有限公司 | 改善嵌合抗原受体表达细胞的功效和扩增的方法 |
| EP3286211A1 (en) | 2015-04-23 | 2018-02-28 | Novartis AG | Treatment of cancer using chimeric antigen receptor and protein kinase a blocker |
| DK3307326T3 (da) | 2015-06-15 | 2020-10-19 | Angiochem Inc | Fremgangsmåder til behandling af leptomeningeal karcinomatose |
| ES2636646B1 (es) * | 2016-04-05 | 2018-08-03 | Universidade De Santiago De Compostela | NUEVOS VEHÍCULOS PARA LA TRANSFECCIÓN DE miRNAs |
| EP3487878A4 (en) | 2016-07-20 | 2020-03-25 | University of Utah Research Foundation | CAR-T CD229 LYMPHOCYTES AND METHODS OF USE |
| CN110225927B (zh) | 2016-10-07 | 2024-01-12 | 诺华股份有限公司 | 用于治疗癌症的嵌合抗原受体 |
| JP2019535750A (ja) | 2016-11-23 | 2019-12-12 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 殺有害生物剤としての２−［３−（アルキルスルホニル）−２Ｈ−インダゾール−２−イル］−３Ｈ−イミダゾ［４，５−ｂ］ピリジン誘導体及び類似化合物 |
| EP3615055A1 (en) | 2017-04-28 | 2020-03-04 | Novartis AG | Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor |
| PL3737685T3 (pl) * | 2018-01-09 | 2023-10-02 | Halcyon Labs Private Limited | Sposób wytwarzania kryzaborolu i jego związków pośrednich |
| WO2019210153A1 (en) | 2018-04-27 | 2019-10-31 | Novartis Ag | Car t cell therapies with enhanced efficacy |
| WO2019213282A1 (en) | 2018-05-01 | 2019-11-07 | Novartis Ag | Biomarkers for evaluating car-t cells to predict clinical outcome |
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| TW444018B (en) * | 1992-12-17 | 2001-07-01 | Pfizer | Pyrazolopyrimidines |
| US7420084B2 (en) * | 2002-07-18 | 2008-09-02 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of nateglinide |
| US8476282B2 (en) * | 2008-11-03 | 2013-07-02 | Intellikine Llc | Benzoxazole kinase inhibitors and methods of use |
| NZ612909A (en) * | 2011-01-10 | 2015-09-25 | Infinity Pharmaceuticals Inc | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
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- 2012-08-10 US US14/238,426 patent/US20150065524A1/en not_active Abandoned
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| MY186267A (en) | 2021-07-01 |
| KR20140079368A (ko) | 2014-06-26 |
| CN103957918A (zh) | 2014-07-30 |
| EP2741749A1 (en) | 2014-06-18 |
| CO6960542A2 (es) | 2014-05-30 |
| IL230850A0 (en) | 2014-03-31 |
| EP2741749A4 (en) | 2015-04-15 |
| ZA201401211B (en) | 2015-12-23 |
| NZ622208A (en) | 2016-04-29 |
| RU2014109023A (ru) | 2015-09-20 |
| PH12014500331A1 (en) | 2014-03-31 |
| EA027970B1 (ru) | 2017-09-29 |
| MX2014001662A (es) | 2014-08-26 |
| SG10201606288TA (en) | 2016-09-29 |
| JP2014521726A (ja) | 2014-08-28 |
| PE20141358A1 (es) | 2014-10-12 |
| CR20140082A (es) | 2014-06-03 |
| ECSP14013236A (es) | 2014-06-30 |
| EA201490446A1 (ru) | 2014-05-30 |
| AU2012294202A1 (en) | 2014-03-06 |
| HK1199203A1 (en) | 2015-06-26 |
| DOP2014000027A (es) | 2014-07-15 |
| BR112014003214A2 (pt) | 2017-03-14 |
| TN2014000063A1 (en) | 2015-07-01 |
| CL2014000343A1 (es) | 2014-10-17 |
| RU2636588C2 (ru) | 2017-11-24 |
| AU2012294202B2 (en) | 2017-02-23 |
| WO2013023184A1 (en) | 2013-02-14 |
| US20150065524A1 (en) | 2015-03-05 |
| SG2014009492A (en) | 2014-09-26 |
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| EEER | Examination request |
Effective date: 20170711 |
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| FZDE | Discontinued |
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