CA2834288A1 - Truncated hiv envelope proteins (env), methods and compositions related thereto - Google Patents

Truncated hiv envelope proteins (env), methods and compositions related thereto Download PDF

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Publication number
CA2834288A1
CA2834288A1 CA2834288A CA2834288A CA2834288A1 CA 2834288 A1 CA2834288 A1 CA 2834288A1 CA 2834288 A CA2834288 A CA 2834288A CA 2834288 A CA2834288 A CA 2834288A CA 2834288 A1 CA2834288 A1 CA 2834288A1
Authority
CA
Canada
Prior art keywords
peptide
acid sequence
seq
amino acid
hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2834288A
Other languages
English (en)
French (fr)
Inventor
Vaniambadi Kalyanaraman
Stephen Whitney
Thomas C. Vancott
Victoria POLONIS
Carl Alving
Gary R. Matyas
Mangala Rao
Mary MAROVICH
Francine MCCUTCHAN
Sodsai TOVANABUTRA
Eric SANDERS-BUELL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henry M Jackson Foundation for Advancedment of Military Medicine Inc
Advanced Bioscience Laboratories Inc
US Army Medical Research and Development Command
Original Assignee
Henry M Jackson Foundation for Advancedment of Military Medicine Inc
Advanced Bioscience Laboratories Inc
US Army Medical Research and Development Command
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henry M Jackson Foundation for Advancedment of Military Medicine Inc, Advanced Bioscience Laboratories Inc, US Army Medical Research and Development Command filed Critical Henry M Jackson Foundation for Advancedment of Military Medicine Inc
Publication of CA2834288A1 publication Critical patent/CA2834288A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16—HIV-1 ; HIV-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2834288A 2011-04-25 2012-04-25 Truncated hiv envelope proteins (env), methods and compositions related thereto Abandoned CA2834288A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161478857P 2011-04-25 2011-04-25
US61/478,857 2011-04-25
PCT/US2012/035026 WO2012149038A1 (en) 2011-04-25 2012-04-25 Truncated hiv envelope proteins (env), methods and compositions related thereto

Publications (1)

Publication Number Publication Date
CA2834288A1 true CA2834288A1 (en) 2012-11-01

Family

ID=46147686

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2834288A Abandoned CA2834288A1 (en) 2011-04-25 2012-04-25 Truncated hiv envelope proteins (env), methods and compositions related thereto

Country Status (10)

Country Link
US (1) US10081658B2 (enExample)
EP (1) EP2701736A1 (enExample)
JP (1) JP6407714B2 (enExample)
KR (1) KR102007444B1 (enExample)
CN (1) CN103945864A (enExample)
AP (1) AP2013007180A0 (enExample)
CA (1) CA2834288A1 (enExample)
HK (1) HK1200329A1 (enExample)
WO (1) WO2012149038A1 (enExample)
ZA (1) ZA201307529B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118515733A (zh) * 2023-02-20 2024-08-20 菲鹏生物股份有限公司 Hiv蛋白及其在检测hiv抗体中的应用

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CA2908538A1 (en) * 2013-04-02 2014-10-09 Barton F. Haynes Recombinant production of hiv-1 envelope glycoproteins
TWI733652B (zh) * 2014-07-11 2021-07-21 美商基利科學股份有限公司 用於治療ＨＩＶ之ｔｏｌｌ樣受體調節劑
JP2017526730A (ja) 2014-09-16 2017-09-14 ギリアード サイエンシーズ， インコーポレイテッド Ｔｏｌｌ様受容体モジュレーターの固体形態
PL3390430T3 (pl) * 2015-12-15 2020-03-31 Janssen Vaccines & Prevention B.V. Antygeny ludzkiego wirusa niedoboru odporności, wektory, kompozycje i sposoby ich zastosowania
US10696985B1 (en) * 2016-06-06 2020-06-30 Vanderbilt University Reversibly crosslinked endosomolytic polymer vesicles for cytosolic drug delivery
KR20220011685A (ko) 2019-05-22 2022-01-28 길리애드 사이언시즈, 인코포레이티드 Tlr7 조절 화합물과 hiv 백신의 조합
EP4076467A4 (en) * 2019-11-04 2023-12-27 Decibel Therapeutics, Inc. VESTIBULAR BEARING CELL PROMOTORS AND USES THEREOF
US12624092B2 (en) * 2020-05-06 2026-05-12 The Regents Of The University Of Michigan Compositions and methods for membrane protein structure determination
CN115838408B (zh) * 2022-12-09 2024-11-29 中国农业大学 一种钙调素结合蛋白MxIQM3及其编码基因与应用

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118515733A (zh) * 2023-02-20 2024-08-20 菲鹏生物股份有限公司 Hiv蛋白及其在检测hiv抗体中的应用

Also Published As

Publication number Publication date
CN103945864A (zh) 2014-07-23
JP2014513956A (ja) 2014-06-19
US10081658B2 (en) 2018-09-25
WO2012149038A1 (en) 2012-11-01
AP2013007180A0 (en) 2013-10-31
HK1200329A1 (en) 2015-08-07
JP6407714B2 (ja) 2018-10-17
KR20140073465A (ko) 2014-06-16
WO2012149038A9 (en) 2019-10-03
EP2701736A1 (en) 2014-03-05
ZA201307529B (en) 2014-06-25
KR102007444B1 (ko) 2019-08-06
US20140220107A1 (en) 2014-08-07

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