CA2832487A1 - Macrophage activating factor for pharmaceutical compositions - Google Patents

Macrophage activating factor for pharmaceutical compositions Download PDF

Info

Publication number
CA2832487A1
CA2832487A1 CA2832487A CA2832487A CA2832487A1 CA 2832487 A1 CA2832487 A1 CA 2832487A1 CA 2832487 A CA2832487 A CA 2832487A CA 2832487 A CA2832487 A CA 2832487A CA 2832487 A1 CA2832487 A1 CA 2832487A1
Authority
CA
Canada
Prior art keywords
composition
protein
gcmaf
cancer
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2832487A
Other languages
English (en)
French (fr)
Inventor
Nobuto Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EFRANAT Ltd
Original Assignee
EFRANAT Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46968677&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2832487(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by EFRANAT Ltd filed Critical EFRANAT Ltd
Publication of CA2832487A1 publication Critical patent/CA2832487A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA2832487A 2011-04-07 2012-04-05 Macrophage activating factor for pharmaceutical compositions Abandoned CA2832487A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161472642P 2011-04-07 2011-04-07
US61/472,642 2011-04-07
PCT/IL2012/000159 WO2012137199A1 (en) 2011-04-07 2012-04-05 Macrophage activating factor for pharmaceutical compositions

Publications (1)

Publication Number Publication Date
CA2832487A1 true CA2832487A1 (en) 2012-10-11

Family

ID=46968677

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2832487A Abandoned CA2832487A1 (en) 2011-04-07 2012-04-05 Macrophage activating factor for pharmaceutical compositions

Country Status (7)

Country Link
US (3) US20140030215A1 (enExample)
EP (1) EP2694088B1 (enExample)
JP (1) JP6113712B2 (enExample)
CN (1) CN103547280B (enExample)
AU (1) AU2012240945B2 (enExample)
CA (1) CA2832487A1 (enExample)
WO (1) WO2012137199A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014279627A1 (en) * 2013-06-09 2015-12-03 Efranat Ltd. Compositions comprising Gc- macrophage activating factor and uses thereof
AT518622A1 (de) * 2016-04-21 2017-11-15 Hg Pharma Gmbh Dimerer Komplex aus selektiv deglycosyliertem Vitamin D bindenden Protein (GcMAF) und Cholecalciferol (Calciol) und Verfahren zu dessen Herstellung
WO2018025270A1 (en) * 2016-08-04 2018-02-08 Efranat Ltd. Enriched modified vitamin d binding protein compositions and use thereof
AU2021398261A1 (en) * 2020-12-08 2023-07-06 Saisei Pharma Co., Ltd. Macrophage activator

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540573A (en) 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US5177001A (en) * 1989-11-20 1993-01-05 Nobuto Yamamoto In vitro enzymatic conversion of glycosylated mammalian vitamin D-binding protein to a potent macrophage activating factor
US5326749A (en) 1989-11-20 1994-07-05 Nobuto Yamamoto Macrophage activating factor from vitamin D binding protein
US5177002A (en) 1989-11-20 1993-01-05 Nobuto Yamamoto In vitro enzymatic conversion of glycosylated human vitamin D binding protein to a potent macrophage activating factor
US5814225A (en) 1994-06-09 1998-09-29 Shanbrom Technologies Llc Iodinated gel filtration media for disinfecting protein solutions
US6096216A (en) 1994-06-09 2000-08-01 American National Red Cross Iodinated matrices for disinfecting biological fluids
US6410269B1 (en) * 1995-06-07 2002-06-25 Nobuto Yamamoto Preparation of potent macrophage activating factors derived from cloned vitamin D binding protein and its domain and their therapeutic usage for cancer, HIV-infection and osteopetrosis
AU2002246849A1 (en) * 2000-11-09 2002-08-06 Northeastern Ohio Universities College Of Medicine Agents and methods for promoting bone growth
US6806355B2 (en) * 2001-08-14 2004-10-19 Statens Serum Institut Purification process for large scale production of Gc-globulin, the Gc-globulin produced hereby, a use of Gc.globulin and a Gc-globulin medicinal product
WO2004005466A2 (en) * 2002-07-03 2004-01-15 Illumigen Biosciences Methods and compositions for diagnosing hepatocellular carcinoma
US8034773B2 (en) * 2004-02-05 2011-10-11 Arizona Biomedical Research Commission Immunostimulatory compositions and uses thereof
WO2005077044A2 (en) * 2004-02-05 2005-08-25 ARIZONA BOARD OF REGENTS, acting for on behalf of ARIZONA STATE UNIVERSITY Rational design and engineering of proteins and peptides for immunomodulation
AU2010289901A1 (en) 2009-08-22 2012-03-15 Charles Knezevich Tumoricidal, bactericidal, or viricidal macrophage activation

Also Published As

Publication number Publication date
EP2694088A4 (en) 2014-12-10
WO2012137199A1 (en) 2012-10-11
US20140030215A1 (en) 2014-01-30
EP2694088A1 (en) 2014-02-12
US20170173115A1 (en) 2017-06-22
EP2694088B1 (en) 2017-06-07
JP2014511857A (ja) 2014-05-19
JP6113712B2 (ja) 2017-04-12
AU2012240945A1 (en) 2013-10-24
US20150361151A1 (en) 2015-12-17
CN103547280B (zh) 2017-06-09
AU2012240945B2 (en) 2017-03-16
CN103547280A (zh) 2014-01-29

Similar Documents

Publication Publication Date Title
US12285462B2 (en) pH-triggered membrane peptide-mediated epitope tethering at cell surfaces
EP4628099A2 (en) Engineered extracellular vesicles and uses thereof
JP7505980B2 (ja) Ｃ３ｂ結合ポリペプチド
RS49533B (sr) Interferonski konjugati
AU4393500A (en) Recombinant human mannan-binding lectin
AU2013243950A1 (en) Modified polynucleotides
US20170173115A1 (en) Macrophage activating factor for pharmaceutical compositions
CA2092720C (en) Macrophage activating factor from vitamin d binding protein
CN102584976B (zh) 一种人血清淀粉样蛋白a1及其制备方法和应用
CN102834111A (zh) 用于生产和纯化重组溶酶体α-甘露糖苷酶的方法
EP0607186B1 (en) Macrophage activating factor from animal vitamin d-binding protein
WO2024110757A1 (en) Control of nanocage self-assembly
HK1194290A (en) Macrophage activating factor for pharmaceutical compositions
US20220233715A1 (en) Aav mutant that efficiently infects supporting cells
EP4122953A1 (en) Fusion protein comprising il-2 protein and cd80 protein fragment or variant thereof, and uses thereof
RU2748383C1 (ru) Способ терапии болезни Тея-Сакса и болезни Сандхоффа с помощью генетически модифицированных мезенхимных стволовых клеток человека со сверхэкспрессией β-гексозаминидазы A
JPS60243018A (ja) ヒト内来性癌制御因子
CN110016082B (zh) MIP3α-FGFR1-PD1/Fc融合蛋白及其核酸分子和应用
KR20250122028A (ko) 신경 퇴행성 질환 유발 인자 제거용 신규 융합단백질 및 이의 용도
AU2004316095A1 (en) Anticancer agent containing BL angiostatin
JPH07238035A (ja) βアミロイド蛋白質分解剤
CN117899223A (zh) 以nup35基因和或以nup35蛋白作为作用靶点的物质的应用及组合物
JP2002502257A (ja) グリコシル化腫瘍壊死因子の調製
JP2007238605A (ja) 精製タンパク質の製造方法
JP2007238606A (ja) 精製タンパク質の製造方法

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170316

FZDE Discontinued

Effective date: 20190405