CA2829558A1 - Pi3 kinase inhibitors and uses thereof - Google Patents
Pi3 kinase inhibitors and uses thereof Download PDFInfo
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- CA2829558A1 CA2829558A1 CA2829558A CA2829558A CA2829558A1 CA 2829558 A1 CA2829558 A1 CA 2829558A1 CA 2829558 A CA2829558 A CA 2829558A CA 2829558 A CA2829558 A CA 2829558A CA 2829558 A1 CA2829558 A1 CA 2829558A1
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| US201161451022P | 2011-03-09 | 2011-03-09 | |
| US61/451,022 | 2011-03-09 | ||
| PCT/US2012/028293 WO2012122383A2 (en) | 2011-03-09 | 2012-03-08 | Pi3 kinase inhibitors and uses thereof |
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| CA2829558A1 true CA2829558A1 (en) | 2012-09-13 |
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| CN (1) | CN103501610A (https=) |
| AU (1) | AU2012225382B2 (https=) |
| CA (1) | CA2829558A1 (https=) |
| WO (1) | WO2012122383A2 (https=) |
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| WO2014186663A2 (en) * | 2013-05-17 | 2014-11-20 | The General Hospital Corporation | Methods for detecting and treating variants of seborrheic keratoses |
| CN104651368B (zh) * | 2013-11-15 | 2017-09-29 | 北京大学 | 一种核酸适配体bc15的核心序列及其类似物和应用 |
| JP6337135B2 (ja) | 2014-02-24 | 2018-06-06 | アルカーメス ファーマ アイルランド リミテッド | フマル酸エステルのスルホンアミドプロドラッグ及びスルフィンアミドプロドラッグ並びに種々の疾患の治療におけるその使用 |
| MA38393B1 (fr) * | 2014-03-13 | 2018-11-30 | Sanofi Sa | Composés hétéroaryle et utilisations associées |
| WO2016172952A1 (zh) * | 2015-04-30 | 2016-11-03 | 江苏挪贝肽医药科技有限公司 | PI4KIIIα蛋白及相关的膜蛋白复合体在治疗阿尔茨海默病中的应用 |
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| WO2020097398A1 (en) | 2018-11-07 | 2020-05-14 | Dana-Farber Cancer Institute, Inc. | Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof |
| WO2020097396A1 (en) | 2018-11-07 | 2020-05-14 | Dana-Farber Cancer Institute, Inc. | Benzimidazole derivatives and aza-benzimidazole derivatives as janus kinase 2 inhibitors and uses thereof |
| CA3181537A1 (en) | 2020-05-06 | 2021-11-11 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
| AU2021324684A1 (en) * | 2020-08-11 | 2023-04-20 | Board Of Trustees Of Michigan State University | Proteasome enhancers and uses thereof |
| EP4267574B1 (en) | 2020-12-23 | 2025-04-23 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
| TW202325289A (zh) | 2021-11-09 | 2023-07-01 | 美商雅捷可斯治療公司 | Ｊａｋ２抑制劑之形式及組合物 |
| JP7782035B2 (ja) | 2021-11-09 | 2025-12-08 | エイジャックス セラピューティクス， インコーポレイテッド | Ｊａｋ２阻害剤としての６－ヘテロアリールオキシベンゾイミダゾール及びアザベンゾイミダゾール |
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| CN115417789B (zh) * | 2022-09-03 | 2023-08-04 | 郑州大学 | 一种治疗帕金森氏病的化合物、其制备方法以及复方药物组合物和应用 |
| AU2024320375A1 (en) * | 2023-08-08 | 2026-02-19 | Lawrence Livermore National Security, Llc | Fused pyridines for the treatment of cancer and other indications |
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| TW200510383A (en) * | 2003-07-16 | 2005-03-16 | Neurogen Corp | Biaryl piperazinyl-pyridine analogues |
| CA2531619A1 (en) * | 2003-07-16 | 2005-01-27 | Neurogen Corporation | Biaryl piperazinyl-pyridine analogues |
| MY145822A (en) * | 2004-08-13 | 2012-04-30 | Neurogen Corp | Substituted biaryl piperazinyl-pyridine analogues |
| CN101080401A (zh) * | 2004-12-13 | 2007-11-28 | 神经能质公司 | 经取代的二芳基类似物 |
| ES2571028T3 (es) * | 2006-12-07 | 2016-05-23 | Genentech Inc | Compuestos inhibidores de fosfoinositida 3-cinasa y métodos de uso |
| WO2008098058A1 (en) * | 2007-02-06 | 2008-08-14 | Novartis Ag | Pi 3-kinase inhibitors and methods of their use |
| US20100311736A1 (en) * | 2007-10-22 | 2010-12-09 | Glaxosmithkline Llc | Pyridosulfonamide derivatives as p13 kinase inhibitors |
| WO2009066084A1 (en) * | 2007-11-21 | 2009-05-28 | F. Hoffmann-La Roche Ag | 2 -morpholinopyrimidines and their use as pi3 kinase inhibitors |
| WO2009070524A1 (en) * | 2007-11-27 | 2009-06-04 | Wyeth | Pyrrolo[3,2-d]pyrimidine compounds and their use as pi3 kinase and mtor kinase inhibitors |
| AU2008343813B2 (en) * | 2007-12-19 | 2012-04-12 | Amgen Inc. | Inhibitors of PI3 kinase |
| GB2465405A (en) * | 2008-11-10 | 2010-05-19 | Univ Basel | Triazine, pyrimidine and pyridine analogues and their use in therapy |
| DE102009015255A1 (de) * | 2009-04-01 | 2010-10-14 | GM Global Technology Operations, Inc., Detroit | Tankklappenmodul |
| JP5649643B2 (ja) * | 2009-04-17 | 2015-01-07 | ワイス・エルエルシー | ピリミジン化合物、ｍＴＯＲキナーゼおよびＰＩ３キナーゼ阻害剤としてのそれらの使用、ならびにそれらの合成 |
| UY32582A (es) * | 2009-04-28 | 2010-11-30 | Amgen Inc | Inhibidores de fosfoinositida 3 cinasa y/u objetivo mamífero |
| EP2475375A4 (en) * | 2009-09-09 | 2013-02-20 | Avila Therapeutics Inc | PI3 KINASE INHIBITORS AND USES THEREOF |
| WO2013033901A1 (en) * | 2011-09-08 | 2013-03-14 | Merck Sharp & Dohme Corp. | Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases |
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- 2012-03-08 JP JP2013557866A patent/JP2014511395A/ja active Pending
- 2012-03-08 CN CN201280021536.0A patent/CN103501610A/zh active Pending
- 2012-03-08 CA CA2829558A patent/CA2829558A1/en not_active Abandoned
- 2012-03-08 AU AU2012225382A patent/AU2012225382B2/en not_active Expired - Fee Related
- 2012-03-08 WO PCT/US2012/028293 patent/WO2012122383A2/en not_active Ceased
- 2012-03-08 US US13/414,918 patent/US20120258967A1/en not_active Abandoned
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| Publication number | Publication date |
|---|---|
| JP2014511395A (ja) | 2014-05-15 |
| AU2012225382B2 (en) | 2016-10-27 |
| CN103501610A (zh) | 2014-01-08 |
| WO2012122383A2 (en) | 2012-09-13 |
| AU2012225382A1 (en) | 2013-10-10 |
| WO2012122383A3 (en) | 2012-12-27 |
| EP2683243A4 (en) | 2014-12-03 |
| US20120258967A1 (en) | 2012-10-11 |
| EP2683243A2 (en) | 2014-01-15 |
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