CA2827057C - Crystalline forms and processes for the preparation of condensed azacycles (cannabinoid receptor modulators) - Google Patents
Crystalline forms and processes for the preparation of condensed azacycles (cannabinoid receptor modulators) Download PDFInfo
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- CA2827057C CA2827057C CA2827057A CA2827057A CA2827057C CA 2827057 C CA2827057 C CA 2827057C CA 2827057 A CA2827057 A CA 2827057A CA 2827057 A CA2827057 A CA 2827057A CA 2827057 C CA2827057 C CA 2827057C
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- crystalline form
- anhydrous crystalline
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- tetrahydro
- pyrazin
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
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| US201161446732P | 2011-02-25 | 2011-02-25 | |
| US61/446,732 | 2011-02-25 | ||
| US201161448542P | 2011-03-02 | 2011-03-02 | |
| US61/448,542 | 2011-03-02 | ||
| PCT/US2012/026506 WO2012116276A1 (en) | 2011-02-25 | 2012-02-24 | Crystalline forms and processes for the preparation of condensed azacycles ( cannabinoid receptor modulators) |
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| CA2827057A1 CA2827057A1 (en) | 2012-08-30 |
| CA2827057C true CA2827057C (en) | 2022-06-07 |
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| CA2827057A Active CA2827057C (en) | 2011-02-25 | 2012-02-24 | Crystalline forms and processes for the preparation of condensed azacycles (cannabinoid receptor modulators) |
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| BR (1) | BR112013021549B1 (OSRAM) |
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| WO (1) | WO2012116276A1 (OSRAM) |
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| KR20200008045A (ko) | 2009-08-28 | 2020-01-22 | 아레나 파마슈티칼스, 인크. | 칸나비노이드 수용체 조절제 |
| US9597340B2 (en) | 2011-02-25 | 2017-03-21 | Arena Pharmaceuticals, Inc. | Cannabinoid receptor modulators |
| MX346533B (es) * | 2011-02-25 | 2017-03-14 | Arena Pharm Inc | Formas cristalinas y procesos para la preparacion de azaciclos condensados (moduladores de receptores canabinoides). |
| JP6043733B2 (ja) | 2011-02-25 | 2016-12-14 | アリーナ ファーマシューティカルズ， インコーポレイテッド | カンナビノイド受容体モジュレーター |
| WO2016085941A1 (en) * | 2014-11-25 | 2016-06-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of cannabinoid receptor modulators |
| CN109310673A (zh) * | 2016-04-10 | 2019-02-05 | 艾尼纳制药公司 | 用选择性cb2受体激动剂治疗的方法 |
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