CA2806464C - Regenerative tissue scaffolds - Google Patents

Regenerative tissue scaffolds Download PDF

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Publication number
CA2806464C
CA2806464C CA2806464A CA2806464A CA2806464C CA 2806464 C CA2806464 C CA 2806464C CA 2806464 A CA2806464 A CA 2806464A CA 2806464 A CA2806464 A CA 2806464A CA 2806464 C CA2806464 C CA 2806464C
Authority
CA
Canada
Prior art keywords
tissue scaffolds
regenerative tissue
mixtures
methods
kits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2806464A
Other languages
English (en)
French (fr)
Other versions
CA2806464A1 (en
Inventor
Rick T. Owens
Laura Elmo
Mike Liu
Yong Mao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LifeCell Corp
Original Assignee
LifeCell Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LifeCell Corp filed Critical LifeCell Corp
Publication of CA2806464A1 publication Critical patent/CA2806464A1/en
Application granted granted Critical
Publication of CA2806464C publication Critical patent/CA2806464C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3612Cartilage, synovial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/362Skin, e.g. dermal papillae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials For Medical Uses (AREA)
CA2806464A 2010-08-10 2011-08-09 Regenerative tissue scaffolds Active CA2806464C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37233910P 2010-08-10 2010-08-10
US61/372,339 2010-08-10
PCT/US2011/047041 WO2012021490A1 (en) 2010-08-10 2011-08-09 Regenerative tissue scaffolds

Publications (2)

Publication Number Publication Date
CA2806464A1 CA2806464A1 (en) 2012-02-16
CA2806464C true CA2806464C (en) 2018-10-23

Family

ID=44511577

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2806464A Active CA2806464C (en) 2010-08-10 2011-08-09 Regenerative tissue scaffolds

Country Status (8)

Country Link
US (1) US20120040013A1 (https=)
EP (3) EP3597226A1 (https=)
JP (1) JP5963208B2 (https=)
CN (1) CN103002927B (https=)
AU (1) AU2011289557B2 (https=)
CA (1) CA2806464C (https=)
ES (2) ES2662331T3 (https=)
WO (1) WO2012021490A1 (https=)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
GB0325129D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus in situ
GB0325126D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus with heat
US11298453B2 (en) 2003-10-28 2022-04-12 Smith & Nephew Plc Apparatus and method for wound cleansing with actives
US8529548B2 (en) 2004-04-27 2013-09-10 Smith & Nephew Plc Wound treatment apparatus and method
US10413644B2 (en) 2004-04-27 2019-09-17 Smith & Nephew Plc Wound treatment apparatus and method
US8469779B1 (en) 2009-01-02 2013-06-25 Lifecell Corporation Method for debristling animal skin
US8637067B1 (en) 2011-03-10 2014-01-28 Lifecell Corporation Elastic tissue matrix derived hydrogel
EP2696908B1 (en) 2011-04-14 2015-03-11 Lifecell Corporation Regenerative materials
US9089523B2 (en) 2011-07-28 2015-07-28 Lifecell Corporation Natural tissue scaffolds as tissue fillers
EP3842078A1 (en) 2011-12-20 2021-06-30 LifeCell Corporation Sheet tissue products
US9549805B2 (en) 2011-12-20 2017-01-24 Lifecell Corporation Flowable tissue products
EP2806907B1 (en) 2012-01-24 2018-11-21 LifeCell Corporation Elongated tissue matrices
BR112014026090A8 (pt) 2012-04-24 2019-08-27 Lifecell Corp composição de matriz tecidual apta a fluir
US11090338B2 (en) 2012-07-13 2021-08-17 Lifecell Corporation Methods for improved treatment of adipose tissue
EP3332816B1 (en) 2012-09-26 2020-11-04 LifeCell Corporation Processed adipose tissue
EP3659633A1 (en) 2013-02-06 2020-06-03 LifeCell Corporation Methods for localized modification of tissue products
US10010658B2 (en) 2013-05-10 2018-07-03 Smith & Nephew Plc Fluidic connector for irrigation and aspiration of wounds
JP6843047B2 (ja) 2014-12-05 2021-03-17 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 支持体として相変化物質を用いた3d印刷
EP3795186A1 (en) * 2015-01-21 2021-03-24 LifeCell Corporation Tissue matrices with controlled porosity or mechanical properties
US11007705B2 (en) 2015-02-13 2021-05-18 University Of Florida Research Foundation, Inc. High speed 3D printing system for wound and tissue replacement
US11390835B2 (en) 2015-05-08 2022-07-19 University Of Florida Research Foundation, Inc. Growth media for three-dimensional cell culture
WO2017040981A1 (en) 2015-09-03 2017-03-09 University Of Florida Research Foundation, Inc. Valve incorporating temporary phase change material
WO2017096263A1 (en) 2015-12-04 2017-06-08 University Of Florida Research Foundation, Incorporated Crosslinkable or functionalizable polymers for 3d printing of soft materials
USD856517S1 (en) 2016-06-03 2019-08-13 Musculoskeletal Transplant Foundation Asymmetric tissue graft
US10792394B2 (en) 2016-06-03 2020-10-06 Lifecell Corporation Methods for localized modification of tissue products
US10945831B2 (en) 2016-06-03 2021-03-16 Musculoskeletal Transplant Foundation Asymmetric tissue graft
US11124644B2 (en) 2016-09-01 2021-09-21 University Of Florida Research Foundation, Inc. Organic microgel system for 3D printing of silicone structures
EP3558405A1 (en) 2016-12-22 2019-10-30 LifeCell Corporation Devices and methods for tissue cryomilling
CN115252910A (zh) 2017-10-18 2022-11-01 生命细胞公司 脂肪组织产品以及产生方法
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
WO2019079672A1 (en) * 2017-10-19 2019-04-25 Lifecell Corporation ACELLULAR TISSUE MATRIX PRODUCTS FLUIDS AND METHODS OF PRODUCTION
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
EP3787702B1 (en) 2018-05-03 2024-08-07 CollPlant Ltd. Dermal fillers and applications thereof
USD895812S1 (en) 2018-09-07 2020-09-08 Musculoskeletal Transplant Foundation Soft tissue repair graft
US10813743B2 (en) 2018-09-07 2020-10-27 Musculoskeletal Transplant Foundation Soft tissue repair grafts and processes for preparing and using same
MX2021014654A (es) 2019-05-30 2022-03-11 Lifecell Corp Implante de mama biologico.
US20230114297A1 (en) 2019-09-25 2023-04-13 Allosource Pre-shaped allograft implant for reconstructive surgical use and methods of manufacture and use, and tools for forming a pre-shaped allograft implant for reconstructive surgical use
FR3110077B1 (fr) * 2020-05-12 2024-12-06 Ph Tech Procédé de fabrication d’un dispositif médical en trois dimensions et dispositif médical obtenu
USD1101168S1 (en) 2023-08-09 2025-11-04 Allosource Acellular dermal matrix sheet allograft

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US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US6166288A (en) 1995-09-27 2000-12-26 Nextran Inc. Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
CA2221195A1 (en) * 1997-11-14 1999-05-14 Chantal E. Holy Biodegradable polymer matrix
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
AU2002329884A1 (en) * 2001-08-27 2003-03-10 Regeneration Technologies, Inc. Processed soft tissue for topical or internal application
ES2535484T3 (es) * 2002-12-12 2015-05-12 Warsaw Orthopedic, Inc. Material compuesto de polímero-hueso que se puede formar o configurar y método para su producción
US20070248575A1 (en) * 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
EP2015707B1 (en) * 2006-05-09 2019-01-23 LifeCell Corporation Reinforced biological tissue
KR100816395B1 (ko) * 2006-09-21 2008-03-27 (주)필미아젠 세포 유래 세포외기질막의 제조방법
CN103108661B (zh) * 2010-03-25 2016-01-20 生命细胞公司 再生性组织支架的制备

Also Published As

Publication number Publication date
EP3323438B1 (en) 2019-10-30
EP2603248B1 (en) 2018-01-03
WO2012021490A1 (en) 2012-02-16
ES2662331T3 (es) 2018-04-06
CA2806464A1 (en) 2012-02-16
AU2011289557A1 (en) 2013-01-24
ES2762118T3 (es) 2020-05-22
JP2013533093A (ja) 2013-08-22
JP5963208B2 (ja) 2016-08-03
AU2011289557B2 (en) 2015-02-05
EP2603248A1 (en) 2013-06-19
EP3323438A1 (en) 2018-05-23
CN103002927A (zh) 2013-03-27
EP3597226A1 (en) 2020-01-22
CN103002927B (zh) 2016-06-15
US20120040013A1 (en) 2012-02-16

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