CA2798280A1 - Compositions de micropastilles comprenant des melanges d'enzymes digestives contenant de la pancreatine - Google Patents
Compositions de micropastilles comprenant des melanges d'enzymes digestives contenant de la pancreatine Download PDFInfo
- Publication number
- CA2798280A1 CA2798280A1 CA2798280A CA2798280A CA2798280A1 CA 2798280 A1 CA2798280 A1 CA 2798280A1 CA 2798280 A CA2798280 A CA 2798280A CA 2798280 A CA2798280 A CA 2798280A CA 2798280 A1 CA2798280 A1 CA 2798280A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- particles
- polymer
- digestive enzyme
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33076810P | 2010-05-03 | 2010-05-03 | |
US61/330,768 | 2010-05-03 | ||
PCT/US2011/035023 WO2011140106A1 (fr) | 2010-05-03 | 2011-05-03 | Compositions de micropastilles comprenant des mélanges d'enzymes digestives contenant de la pancréatine |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2798280A1 true CA2798280A1 (fr) | 2011-11-10 |
Family
ID=44904036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2798280A Abandoned CA2798280A1 (fr) | 2010-05-03 | 2011-05-03 | Compositions de micropastilles comprenant des melanges d'enzymes digestives contenant de la pancreatine |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP2566466A1 (fr) |
JP (1) | JP2013525488A (fr) |
CN (1) | CN102946872A (fr) |
AU (1) | AU2011248293A1 (fr) |
CA (1) | CA2798280A1 (fr) |
CO (1) | CO6640298A2 (fr) |
IL (1) | IL222796A0 (fr) |
MX (1) | MX2012012794A (fr) |
RU (1) | RU2012148776A (fr) |
WO (1) | WO2011140106A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20170052520A (ko) * | 2013-11-05 | 2017-05-12 | 앨러간 파마슈티컬스 인터내셔널 리미티드 | 고효능 판크레아틴 약학적 조성물 |
JP6672277B2 (ja) * | 2014-10-08 | 2020-04-01 | シンセティック・バイオロジクス・インコーポレイテッド | ベータラクタマーゼ製剤およびその使用 |
CN104906565B (zh) * | 2015-05-13 | 2018-06-19 | 西南大学 | 一种胰酶肠溶微丸及其制备方法 |
CN106237315A (zh) * | 2016-08-02 | 2016-12-21 | 马南行 | 一种外用治疗糖尿病的组合物及其制备方法 |
IT201700021852A1 (it) * | 2017-02-27 | 2018-08-27 | Bioscreen Tech S R L | Composizione a rilascio controllato di sostanze fisiologicamente attive e processo per la sua preparazione |
IT201700021879A1 (it) | 2017-02-27 | 2018-08-27 | Bioscreen Tech S R L | Composizione a rilascio controllato di sostanze fisiologicamente attive e processo per la sua preparazione |
DE102017104501A1 (de) | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Pharmazeutische Zusammensetzung umfassend einen Träger und einen Überzug enthaltend wenigstens eine Lipase |
DE102017104482A1 (de) | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Pharmazeutische Zusammensetzung umfassend Pankreatin und einen lipasehaltigen Überzug |
SG11202007976WA (en) * | 2018-02-23 | 2020-09-29 | MUCPharm Pty Ltd | Formulations containing mucin-affecting proteases |
CN108531538A (zh) * | 2018-04-08 | 2018-09-14 | 武汉藤欣生物工程有限公司 | 一种酶法制备植物甾醇酯的方法 |
NL2021893B1 (en) | 2018-10-26 | 2020-05-13 | Citeq B V | Biological pest control agent |
CN110075279A (zh) * | 2019-04-25 | 2019-08-02 | 淮安麦德森制药有限公司 | 胰酶微球及其生产方法 |
CN110331138A (zh) * | 2019-06-29 | 2019-10-15 | 南京永正生物科技有限公司 | 一种生物复合酶微胶囊的生产工艺 |
RU2706003C1 (ru) * | 2019-09-09 | 2019-11-13 | Акционерное общество "АВВА РУС" | Микрогранулы, содержащие панкреатин |
CN112220916A (zh) * | 2020-10-26 | 2021-01-15 | 西南药业股份有限公司 | 生物酶片剂的制备工艺及其产品 |
CN114767639A (zh) * | 2022-05-13 | 2022-07-22 | 天津博菲德科技有限公司 | 一种耐酸型酶制剂颗粒及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4227385A1 (de) * | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
NZ514826A (en) * | 1999-03-17 | 2003-08-29 | Solvay Pharm Gmbh | Medicinal product for the treatment of diabetes |
IT1319655B1 (it) * | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
US7578951B2 (en) * | 2004-01-27 | 2009-08-25 | Hewlett-Packard Development Company, L.P. | Method of making microcapsules utilizing a fluid ejector |
WO2005092297A2 (fr) * | 2004-03-03 | 2005-10-06 | Teva Pharmaceutical Industries Ltd. | Composition pharmaceutique stable comprenant un medicament labile en milieu acide |
NZ565959A (en) * | 2005-08-15 | 2011-10-28 | Solvay Pharm Gmbh | Pancreatin micropellet cores suitable for enteric coating |
US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
WO2007020259A2 (fr) * | 2005-08-15 | 2007-02-22 | Solvay Pharmaceuticals Gmbh | Compositions pharmaceutiques a liberation controlee destinees a des medicaments acido-labiles |
WO2008102264A2 (fr) * | 2007-02-20 | 2008-08-28 | Eurand Pharmaceuticals Limited | Compositions stables à base d'enzymes digestives |
CN101279091A (zh) * | 2007-04-04 | 2008-10-08 | 常州市第四制药厂有限公司 | 胰酶肠溶微丸及制备方法 |
-
2011
- 2011-05-03 RU RU2012148776/15A patent/RU2012148776A/ru unknown
- 2011-05-03 MX MX2012012794A patent/MX2012012794A/es not_active Application Discontinuation
- 2011-05-03 EP EP11778183A patent/EP2566466A1/fr not_active Withdrawn
- 2011-05-03 CN CN2011800303935A patent/CN102946872A/zh active Pending
- 2011-05-03 CA CA2798280A patent/CA2798280A1/fr not_active Abandoned
- 2011-05-03 JP JP2013509183A patent/JP2013525488A/ja active Pending
- 2011-05-03 WO PCT/US2011/035023 patent/WO2011140106A1/fr active Application Filing
- 2011-05-03 AU AU2011248293A patent/AU2011248293A1/en not_active Abandoned
-
2012
- 2012-11-01 IL IL222796A patent/IL222796A0/en unknown
- 2012-11-30 CO CO12217880A patent/CO6640298A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2011140106A1 (fr) | 2011-11-10 |
CO6640298A2 (es) | 2013-03-22 |
JP2013525488A (ja) | 2013-06-20 |
AU2011248293A1 (en) | 2012-11-15 |
IL222796A0 (en) | 2012-12-31 |
EP2566466A1 (fr) | 2013-03-13 |
RU2012148776A (ru) | 2014-06-10 |
MX2012012794A (es) | 2013-03-12 |
CN102946872A (zh) | 2013-02-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |
Effective date: 20160504 |