CA2796744A1 - Metabolites synthetiques d'omega-carboxyaryldiphenylurees fluorosubstituees pour le traitement et la prevention de maladies et d'etats - Google Patents
Metabolites synthetiques d'omega-carboxyaryldiphenylurees fluorosubstituees pour le traitement et la prevention de maladies et d'etats Download PDFInfo
- Publication number
- CA2796744A1 CA2796744A1 CA2796744A CA2796744A CA2796744A1 CA 2796744 A1 CA2796744 A1 CA 2796744A1 CA 2796744 A CA2796744 A CA 2796744A CA 2796744 A CA2796744 A CA 2796744A CA 2796744 A1 CA2796744 A1 CA 2796744A1
- Authority
- CA
- Canada
- Prior art keywords
- synthetic
- formula
- metabolites
- diseases
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32529410P | 2010-04-17 | 2010-04-17 | |
US61/325,294 | 2010-04-17 | ||
PCT/US2011/032835 WO2011130728A1 (fr) | 2010-04-17 | 2011-04-18 | Métabolites synthétiques d'oméga-carboxyaryldiphénylurées fluorosubstituées pour le traitement et la prévention de maladies et d'états |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2796744A1 true CA2796744A1 (fr) | 2011-10-20 |
Family
ID=44144967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2796744A Abandoned CA2796744A1 (fr) | 2010-04-17 | 2011-04-18 | Metabolites synthetiques d'omega-carboxyaryldiphenylurees fluorosubstituees pour le traitement et la prevention de maladies et d'etats |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN103079567A (fr) |
CA (1) | CA2796744A1 (fr) |
WO (1) | WO2011130728A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102643229A (zh) * | 2012-01-17 | 2012-08-22 | 湖南有色凯铂生物药业有限公司 | N-((4-氯-3-三氟甲基)苯基)-n’-((2-氟-4-(2-氨基甲酰基)-4-吡啶基氧)苯基)脲及其作为抗癌药物的应用 |
CN102885814A (zh) * | 2012-01-17 | 2013-01-23 | 湖南有色凯铂生物药业有限公司 | 一种化合物及其作为抗癌药物的应用 |
CN103508944A (zh) * | 2012-06-25 | 2014-01-15 | 湖南有色凯铂生物药业有限公司 | N-((4-氯-3-三氟甲基)苯基)-n’-((2-氟-4-(2-氨基甲酰基)-4-吡啶基氧)苯基)脲的晶型a及其制备方法 |
CN103058922B (zh) * | 2012-09-06 | 2014-07-16 | 湖南有色凯铂生物药业有限公司 | 用于抗肿瘤药物的芳香脲的晶型及其制备方法 |
CN104250226B (zh) * | 2013-06-27 | 2019-04-26 | 常州方楠医药技术有限公司 | 一种制备瑞格菲尼中间体的方法 |
CN104736521B (zh) * | 2013-09-12 | 2016-10-12 | 杭州普晒医药科技有限公司 | 瑞格非尼盐晶型及其制备方法和用途 |
CN103923001B (zh) * | 2014-04-30 | 2016-02-10 | 药源药物化学(上海)有限公司 | 瑞戈非尼盐及其晶型、制备方法 |
CN105218439B (zh) * | 2014-06-06 | 2018-11-20 | 连云港润众制药有限公司 | 一种瑞格非尼的晶体及其制备方法 |
CN105566215B (zh) * | 2014-10-17 | 2018-02-16 | 沈阳药科大学 | 一种瑞戈非尼的制备方法 |
CN104592105B (zh) * | 2015-02-10 | 2017-01-18 | 杭州朱养心药业有限公司 | 瑞戈非尼及其制法 |
CN107921173B (zh) * | 2015-08-03 | 2021-07-06 | 富士胶片株式会社 | 细胞结构体、非人模型动物、非人模型动物的制造方法及被检验物质的评价方法 |
CN109796401B (zh) * | 2019-04-04 | 2023-10-17 | 新乡双鹭药业有限公司 | 一种瑞戈非尼原料药的制备方法 |
CN112587485A (zh) * | 2021-01-08 | 2021-04-02 | 湖南南新制药股份有限公司 | 一种药物固体分散体及其制备方法 |
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CA1340807C (fr) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Procede d'amplification d'une sequence d'acide nucleique |
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-
2011
- 2011-04-18 WO PCT/US2011/032835 patent/WO2011130728A1/fr active Application Filing
- 2011-04-18 CA CA2796744A patent/CA2796744A1/fr not_active Abandoned
- 2011-04-18 CN CN2011800298301A patent/CN103079567A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2011130728A1 (fr) | 2011-10-20 |
CN103079567A (zh) | 2013-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |
Effective date: 20170418 |