CA2788582C - Nitric oxide delivery system - Google Patents

Nitric oxide delivery system Download PDF

Info

Publication number
CA2788582C
CA2788582C CA2788582A CA2788582A CA2788582C CA 2788582 C CA2788582 C CA 2788582C CA 2788582 A CA2788582 A CA 2788582A CA 2788582 A CA2788582 A CA 2788582A CA 2788582 C CA2788582 C CA 2788582C
Authority
CA
Canada
Prior art keywords
gas
nitrogen dioxide
reservoir
tube
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2788582A
Other languages
English (en)
French (fr)
Other versions
CA2788582A1 (en
Inventor
David H. Fine
Ryan Denton
Gregory Vasquez
Bryan Johnson
Original Assignee
Vero Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vero Biotech Inc filed Critical Vero Biotech Inc
Publication of CA2788582A1 publication Critical patent/CA2788582A1/en
Application granted granted Critical
Publication of CA2788582C publication Critical patent/CA2788582C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A61M2016/1035—Measuring a parameter of the content of the delivered gas the anaesthetic agent concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2788582A 2010-02-01 2011-01-31 Nitric oxide delivery system Active CA2788582C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30042510P 2010-02-01 2010-02-01
US61/300,425 2010-02-01
PCT/US2011/023172 WO2011094684A1 (en) 2010-02-01 2011-01-31 Nitric oxide delivery system

Publications (2)

Publication Number Publication Date
CA2788582A1 CA2788582A1 (en) 2011-08-04
CA2788582C true CA2788582C (en) 2020-01-07

Family

ID=44319849

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2788582A Active CA2788582C (en) 2010-02-01 2011-01-31 Nitric oxide delivery system

Country Status (7)

Country Link
US (1) US20110240019A1 (https=)
EP (1) EP2531249B1 (https=)
JP (1) JP5965845B2 (https=)
AU (1) AU2011210543B2 (https=)
CA (1) CA2788582C (https=)
ES (1) ES2873089T3 (https=)
WO (1) WO2011094684A1 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005277397B2 (en) 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7618594B2 (en) * 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
CA2713049C (en) 2008-01-28 2017-02-28 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
EP2445508B1 (en) 2009-06-22 2018-11-14 VERO Biotech LLC Nitric oxide therapies
CA2819854A1 (en) 2010-12-03 2012-06-07 Geno Llc Nitric oxide treatments
AU2013257484B2 (en) * 2011-01-06 2017-09-28 Mallinckrodt Hospital Products IP Limited Nitric oxide delivery device
DK2661300T3 (en) 2011-01-06 2018-01-15 Ino Therapeutics Llc Gas supply device and system
EP3391891A3 (en) * 2011-06-10 2019-01-02 VERO Biotech LLC Pressurized vessel of nitric oxide (no)
US20150272988A1 (en) 2012-03-07 2015-10-01 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
MX368858B (es) * 2012-03-15 2019-10-18 Mallinckrodt Hospital Products Ip Ltd Metodos para administrar altas concentraciones de oxido nitrico.
US9423051B2 (en) * 2012-08-17 2016-08-23 The Coca-Cola Company Dispensing carbonated beverages from a closed package
JP2016500550A (ja) * 2012-11-05 2016-01-14 ゲノ エルエルシー 一酸化窒素を含むガスを混合する方法
WO2014136111A2 (en) 2013-03-07 2014-09-12 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
WO2014160373A1 (en) * 2013-03-13 2014-10-02 Ino Therapeutics Llc Devices and methods for monitoring oxygenation during treatment with delivery of nitric oxide
JP6072611B2 (ja) * 2013-05-28 2017-02-01 住友精化株式会社 二酸化窒素の変換方法および二酸化窒素変換装置
US10525226B2 (en) * 2014-05-14 2020-01-07 Mallinckrodt Hospital Products IP Limited Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
CA2987046A1 (en) * 2015-05-25 2016-12-01 Geno Llc Nitric oxide treatment system and method
EP4512819A3 (en) * 2015-08-12 2025-08-06 The General Hospital Corporation Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders
MX2018004020A (es) 2015-10-01 2018-09-11 Mallinckrodt Hospital Products Ip Ltd Dispositivo y método para la dispersión de no de concentración alta con gas de terapia de inhalación.
JP2019506259A (ja) * 2015-12-11 2019-03-07 ベロ バイオテック エルエルシー 線維症に対処するために一酸化窒素を含むガスを投与するための方法及び装置
WO2018157175A1 (en) 2017-02-27 2018-08-30 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
BR112019016708B1 (pt) 2017-02-27 2024-01-30 Third Pole, Inc Sistemas de geração de óxido nítrico
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
JP7263261B2 (ja) * 2017-06-08 2023-04-24 ケース ウエスタン リザーブ ユニバーシティ 制御された濃度で送達を行うための気化システム
US11754538B1 (en) * 2018-07-18 2023-09-12 Vero Biotech Inc. Method and apparatus for automatic calibration
US11672938B1 (en) * 2018-07-18 2023-06-13 Vero Biotech LLC Start-up protocols for nitric oxide delivery device
US12544403B2 (en) 2019-01-10 2026-02-10 The General Hospital Corporation Methods to treat mitochondrial-associated dysfunctions or diseases
CN114269685A (zh) 2019-05-15 2022-04-01 第三极股份有限公司 用于一氧化氮生成的电极
WO2020232414A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Architectures for production of nitric oxide
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
EP4069069A4 (en) 2020-01-11 2024-07-03 Third Pole, Inc. SYSTEMS AND METHODS FOR NITROGEN OXIDE PRODUCTION WITH HUMIDITY CONTROL
US12059531B2 (en) * 2020-06-07 2024-08-13 Alti Llc Nitric oxide generation, delivery, and monitoring system
EP4167920A4 (en) 2020-06-18 2024-06-12 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
EP4405019A4 (en) 2021-09-23 2025-07-16 Third Pole Inc SYSTEMS AND METHODS FOR PROVIDING NITRIC OXIDE
WO2023201363A2 (en) 2022-04-14 2023-10-19 Third Pole, Inc. Delivery of medicinal gas in a liquid medium
KR102831194B1 (ko) * 2022-12-22 2025-07-09 성균관대학교산학협력단 관류 mri 획득 방법 및 시스템

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3521865A (en) * 1968-05-20 1970-07-28 Du Pont Generation of accurately known vapor concentrations by permeation
US3856204A (en) * 1973-03-12 1974-12-24 Ecology Board Inc Gas emitting device
US4399942A (en) * 1981-11-09 1983-08-23 Gc Industries Gas emitting device
US5324478A (en) * 1987-08-14 1994-06-28 American Air Liquide Gas generating apparatus
US5653885A (en) * 1990-07-13 1997-08-05 Isco, Inc. Apparatus and method for supercritical fluid extraction
US5156334A (en) * 1990-08-15 1992-10-20 Kimbell Charles L Gas permeation system
US5396882A (en) * 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
DE59409834D1 (de) * 1993-04-17 2001-09-27 Messer Griesheim Austria Ges M Gerät zur kontrollierten Zudosierung von NO zur Atemluft von Patienten
GB9320978D0 (en) * 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
US5558083A (en) * 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
JP3142716B2 (ja) * 1994-04-28 2001-03-07 裕一 石部 呼吸器への一酸化窒素の供給装置
DE19612289A1 (de) * 1996-03-28 1997-10-02 Messer Griesheim Gmbh Verfahren und Vorrichtung zur Minderung von Risiken bei der inhalativen NO-Therapie
US5692495A (en) * 1996-04-02 1997-12-02 The Boc Group, Inc. Method and apparatus for the production of nitric oxide gas mixture
US5743251A (en) * 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
US6564656B1 (en) * 1998-05-19 2003-05-20 Markes International Limited Sampling device
US6089229A (en) * 1998-05-26 2000-07-18 Datex-Ohmeda, Inc. High concentration no pulse delivery device
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
ES2473591T3 (es) * 2001-07-31 2014-07-07 Philip Morris Products S.A. Método y aparato para generar líquidos volatilizados
US6681769B2 (en) * 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US20080029093A1 (en) * 2004-05-11 2008-02-07 Alex Stenzler Intermittent Dosing Of Nitric Oxide Gas
AU2005277397B2 (en) * 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7618594B2 (en) * 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US20070181126A1 (en) * 2006-02-08 2007-08-09 Tolmie Craig R Method and apparatus for ventilating a patient with a breathing gas mixture formed from nitric oxide, air, and oxygen
EP2131903B1 (en) * 2007-03-23 2018-01-24 Geno LLC Conversion of nitrogen dioxide (no2) to nitric oxide (no)
CA2713049C (en) * 2008-01-28 2017-02-28 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
WO2010011928A1 (en) * 2008-07-24 2010-01-28 Geno Llc Methods for diagnosing and treating a heart condition in a patient
CA2781295C (en) 2009-11-20 2018-02-13 Geno Llc Nitric oxide delivery system

Also Published As

Publication number Publication date
JP2013518615A (ja) 2013-05-23
US20110240019A1 (en) 2011-10-06
AU2011210543A1 (en) 2012-08-23
EP2531249A4 (en) 2014-08-27
EP2531249B1 (en) 2021-03-24
CA2788582A1 (en) 2011-08-04
JP5965845B2 (ja) 2016-08-10
AU2011210543B2 (en) 2016-02-25
EP2531249A1 (en) 2012-12-12
ES2873089T3 (es) 2021-11-03
WO2011094684A1 (en) 2011-08-04

Similar Documents

Publication Publication Date Title
CA2788582C (en) Nitric oxide delivery system
US12383692B2 (en) Systems and methods for synthesis of nitric oxide
US20220016379A1 (en) Delivery of high concentration nitric oxide
CA2278053C (en) Controlled gas supply system
US5839433A (en) Nitric oxide treatment
AU2013337351B2 (en) Method of mixing gases including nitric oxide
HK40041930B (en) Systems and methods for synthesis of nitric oxide
HK40041930A (en) Systems and methods for synthesis of nitric oxide
Gomez et al. Delivery of inhaled nitric oxide from a 10% source by gas phase titration

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20160129

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD

Year of fee payment: 14

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250121

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20250130

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250130

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-4-4-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260316