CA2787978A1 - Interferon-beta for anti-virus therapy for respiratory diseases - Google Patents

Interferon-beta for anti-virus therapy for respiratory diseases Download PDF

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Publication number
CA2787978A1
CA2787978A1 CA2787978A CA2787978A CA2787978A1 CA 2787978 A1 CA2787978 A1 CA 2787978A1 CA 2787978 A CA2787978 A CA 2787978A CA 2787978 A CA2787978 A CA 2787978A CA 2787978 A1 CA2787978 A1 CA 2787978A1
Authority
CA
Canada
Prior art keywords
cells
ifn
infection
agent
asthmatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2787978A
Other languages
English (en)
French (fr)
Inventor
Donna Elizabeth Davies
Stephen Holgate
Peter Alexander Blanch Wark
Sebastian L. Johnston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southampton
Original Assignee
University of Southampton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southampton filed Critical University of Southampton
Publication of CA2787978A1 publication Critical patent/CA2787978A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CA2787978A 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases Abandoned CA2787978A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0405634.7A GB0405634D0 (en) 2004-03-12 2004-03-12 Anti-virus therapy for respiratory diseases
GB0405634.7 2004-03-12
CA2558212A CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2558212A Division CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Publications (1)

Publication Number Publication Date
CA2787978A1 true CA2787978A1 (en) 2005-09-22

Family

ID=32117582

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2787978A Abandoned CA2787978A1 (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases
CA2558212A Expired - Lifetime CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2558212A Expired - Lifetime CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Country Status (12)

Country Link
US (3) US7569216B2 (cg-RX-API-DMAC7.html)
EP (2) EP1734987B1 (cg-RX-API-DMAC7.html)
JP (2) JP4807526B2 (cg-RX-API-DMAC7.html)
AT (1) ATE466591T1 (cg-RX-API-DMAC7.html)
CA (2) CA2787978A1 (cg-RX-API-DMAC7.html)
DE (1) DE602005021078D1 (cg-RX-API-DMAC7.html)
DK (1) DK1734987T3 (cg-RX-API-DMAC7.html)
ES (1) ES2343732T3 (cg-RX-API-DMAC7.html)
GB (1) GB0405634D0 (cg-RX-API-DMAC7.html)
PL (1) PL1734987T3 (cg-RX-API-DMAC7.html)
PT (1) PT1734987E (cg-RX-API-DMAC7.html)
WO (1) WO2005087253A2 (cg-RX-API-DMAC7.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0405634D0 (en) 2004-03-12 2004-04-21 Univ Southampton Anti-virus therapy for respiratory diseases
US8318423B2 (en) * 2004-07-06 2012-11-27 Focus Diagnostics, Inc. Methods and compositions for detecting rhinoviruses
EP1922081B1 (en) * 2005-09-09 2012-08-15 Imperial Innovations Limited Interferon lambda therapy for treatment of respiratory diseases
AU2005336519B2 (en) * 2005-09-20 2012-05-10 New York University Method of treating pulmonary disease with interferons
DE102006022877B4 (de) 2006-05-15 2009-01-29 Sartorius Stedim Biotech Gmbh Verfahren zur Bestimmung der Viabilität von Zellen in Zellkulturen
US7871603B2 (en) 2007-05-18 2011-01-18 Synairgen Research Limited Interferon-beta and/or lambda for use in treating rhinovirus infection in the elderly
GB0713402D0 (en) * 2007-07-11 2007-08-22 Cardiff & Vale Nhs Trust A method of diagnosing a condition using a neural network
BRPI0819932A2 (pt) * 2007-12-13 2019-07-30 Glaxo Group Ltd composição, uso de uma composição, dispositivo nebulizador, inalador ou intranasal, processos para produzir uma composição farmacêutica e uma composição polipeptídica, e, uso de um tampão fisiologicamente aceitável.
AU2009344851A1 (en) * 2008-12-19 2011-06-23 The Regents Of The University Of California Use of epidermal growth factor inhibitors in the treatment of viral infection
EP2506759A4 (en) 2009-12-02 2015-05-20 Neetour Medical Ltd SURVEILLANCE BASED ON HEMODYNAMIA AND ASSESSMENT OF RESPIRATORY DISEASES
DK2544705T3 (en) * 2010-03-12 2016-09-19 Synairgen Res Ltd INTERFERON BETA TO USE IN THE LOWER AIR TRANSMISSION CAUSED BY INFLUENZA
PL3669892T3 (pl) 2010-09-22 2024-10-07 Ena Respiratory Pty Ltd Kompozycja do zastosowania w metodzie immunostymulacyjnej
JP6730926B2 (ja) 2014-01-08 2020-07-29 プロージット ソウル バイオテクノロジー (ベイジン) カンパニー リミテッド 融合ポリペプチドおよび使用方法
JP7317796B2 (ja) * 2017-07-24 2023-07-31 ノババックス,インコーポレイテッド 呼吸器疾患を治療するための方法および組成物
FI3728289T3 (fi) 2017-12-21 2025-11-11 Axelia Oncology Pty Ltd Optimoidut yhdisteet
WO2020168033A2 (en) * 2019-02-13 2020-08-20 University Of Florida Research Foundation, Inc. Targeting lung-resident tnfr2+ cdc2 (r2d2) subpopulation to treat asthma
KR20220050873A (ko) 2019-06-26 2022-04-25 악셀리아 온콜로지 피티와이 리미티드 신규한 분자
US20230338475A1 (en) 2020-07-20 2023-10-26 Synairgen Research Limited USE OF INHALED INTERFERON-BETA TO IMPROVE OUTCOME IN SARS-CoV-2 INFECTED PATIENTS
GB202014114D0 (en) * 2020-09-08 2020-10-21 Synairgen Res Ltd Use of inhaled interferon-beta to treat virus-induced exacerbations in copd patients undergoing treatment with a systemic corticosteroid
DK4240396T5 (da) * 2020-11-04 2025-04-07 Ethris Gmbh Ifn-lambda-mrna til behandling af virusinfektioner
US20250281576A1 (en) * 2021-01-13 2025-09-11 Abion Inc. Prophylactic administration method against respiratory virus, comprising administering interferon-beta to potential respiratory virus-infected subject

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596260B1 (en) * 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
ES2245780T3 (es) * 1994-05-18 2006-01-16 Nektar Therapeutics Metodos y composiciones para la formulacion de interferones como un polvo seco.
US6030609A (en) * 1995-05-19 2000-02-29 Case Western Reserve University Method and composition for treating paramyxovirus
US20010031253A1 (en) * 1996-07-24 2001-10-18 Gruenberg Micheal L. Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
AU780270B2 (en) * 2000-02-23 2005-03-10 Association Francaise Contre Les Myopathies Treatment of immune diseases
GB2362884A (en) 2000-05-30 2001-12-05 Isis Innovation Extended duration of airway gene therapy
EP1334128A2 (en) 2000-11-02 2003-08-13 Maxygen Aps New multimeric interferon beta polypeptides
WO2002072019A2 (en) * 2001-03-13 2002-09-19 Vical Incorporated Interferon-beta polynucleotide therapy for autoimmune and inflammatory diseases
AU2003215136A1 (en) 2002-02-08 2003-09-02 University Of Medicine And Dentistry Of New Jersey Ifn-a/b-independent mechanism of antiviral protection
US20040037809A1 (en) * 2002-06-28 2004-02-26 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of interferon beta
WO2004037995A2 (en) 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
US7157559B2 (en) 2003-08-07 2007-01-02 Zymogenetics, Inc. Homogeneous preparations of IL-28 and IL-29
GB0405634D0 (en) 2004-03-12 2004-04-21 Univ Southampton Anti-virus therapy for respiratory diseases
WO2005097165A2 (en) 2004-04-02 2005-10-20 Zymogenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection

Also Published As

Publication number Publication date
US9089535B2 (en) 2015-07-28
HK1097181A1 (en) 2007-06-22
CA2558212C (en) 2012-11-27
GB0405634D0 (en) 2004-04-21
JP4807526B2 (ja) 2011-11-02
JP2007528890A (ja) 2007-10-18
DE602005021078D1 (de) 2010-06-17
DK1734987T3 (da) 2010-08-30
US8273342B2 (en) 2012-09-25
US20090257980A1 (en) 2009-10-15
WO2005087253A3 (en) 2005-11-24
EP2206512A3 (en) 2013-01-09
JP2011144201A (ja) 2011-07-28
PT1734987E (pt) 2010-07-06
EP2206512A2 (en) 2010-07-14
WO2005087253A2 (en) 2005-09-22
EP1734987A2 (en) 2006-12-27
ES2343732T3 (es) 2010-08-09
EP1734987B1 (en) 2010-05-05
CA2558212A1 (en) 2005-09-22
US20130209399A1 (en) 2013-08-15
US20070134763A1 (en) 2007-06-14
PL1734987T3 (pl) 2010-10-29
US7569216B2 (en) 2009-08-04
ATE466591T1 (de) 2010-05-15

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140219

FZDE Discontinued

Effective date: 20151222