CA2782176C - Methods and apparatus for segregation of particles, including segregation and proliferation of fetal and stem cells - Google Patents
Methods and apparatus for segregation of particles, including segregation and proliferation of fetal and stem cells Download PDFInfo
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- G—PHYSICS
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- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
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- G—PHYSICS
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- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0272—Investigating particle size or size distribution with screening; with classification by filtering
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
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- B01L2300/00—Additional constructional details
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- B01L2300/0809—Geometry, shape and general structure rectangular shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2300/00—Additional constructional details
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- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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US61/264,918 | 2009-11-30 | ||
PCT/US2010/058172 WO2011066497A2 (en) | 2009-11-30 | 2010-11-29 | Methods and apparatus for segregation of particles, including segregation and proliferation of fetal and stem cells |
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CA2782176A Active CA2782176C (en) | 2009-11-30 | 2010-11-29 | Methods and apparatus for segregation of particles, including segregation and proliferation of fetal and stem cells |
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JP (2) | JP2013511992A (ja) |
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BR (1) | BR112012013034A2 (ja) |
CA (1) | CA2782176C (ja) |
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WO (1) | WO2011066497A2 (ja) |
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EP2587248A1 (en) * | 2011-10-25 | 2013-05-01 | Koninklijke Philips Electronics N.V. | Filtering particles from blood or other media |
US9631179B2 (en) | 2013-03-15 | 2017-04-25 | Angle North America, Inc. | Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge |
WO2016069624A1 (en) | 2014-10-27 | 2016-05-06 | Board Of Regents, The University Of Texas System | High-throughput imaging platform |
CN105176812B (zh) * | 2015-07-28 | 2017-10-03 | 浙江奥瑞健生物技术有限公司 | 一种干细胞球切割收集装置及干细胞球的切割分离传代方法 |
CA2995474C (en) * | 2015-08-18 | 2022-04-26 | National Health Research Institutes | A microfluidic hydrodynamic shuttling chip device for highthroughput multiple single cells capture |
GB201704766D0 (en) * | 2017-01-05 | 2017-05-10 | Illumia Inc | System and methods for selective effluent collection |
EP3561038A1 (en) * | 2018-04-24 | 2019-10-30 | Bayer AG | Cell separator |
US11389799B2 (en) * | 2019-01-17 | 2022-07-19 | The Regents Of The University Of Michigan | Microfluidic device for size and deformability measurements and applications thereof |
US20220146400A1 (en) * | 2019-02-27 | 2022-05-12 | Kyocera Corporation | Particle separating and measuring device and particle separating and measuring apparatus |
CN109810894B (zh) * | 2019-03-01 | 2022-06-10 | 长春理工大学 | 一种基于光诱导介电泳的群细胞三维结构操纵与构建系统及方法 |
WO2021015089A1 (ja) * | 2019-07-23 | 2021-01-28 | 国立大学法人佐賀大学 | 剪断処理による微細藻類の外被破壊法及び外被破壊システム |
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US6008040A (en) * | 1995-07-07 | 1999-12-28 | Synosys, Inc. | Procedures for efficient separation of cells, cellular materials and proteins |
WO2003008931A2 (en) * | 2001-07-17 | 2003-01-30 | Georgi Hvichia | Microstructure for particle and cell separation, identification, sorting, and manipulation |
US6783928B2 (en) * | 2001-07-17 | 2004-08-31 | Georgi Hvichia | Microstructures for cell proliferation assays and semen analysis |
JP2006501449A (ja) * | 2002-09-27 | 2006-01-12 | ザ ジェネラル ホスピタル コーポレーション | 細胞分離のためのマイクロ流体デバイスおよびその使用 |
EP1671101A1 (en) * | 2003-10-03 | 2006-06-21 | Vrije Universiteit Brussel | Method and device for size-separating particles present in a fluid |
WO2009131645A2 (en) * | 2008-04-23 | 2009-10-29 | Parsortix, Inc. | Methods and apparatus for segregation of particles |
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Also Published As
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JP2013511992A (ja) | 2013-04-11 |
AU2010246381B2 (en) | 2013-08-15 |
AU2010246381A1 (en) | 2010-12-16 |
WO2011066497A3 (en) | 2011-11-17 |
CA2782176A1 (en) | 2011-06-03 |
CN102695804B (zh) | 2014-09-03 |
JP2016208978A (ja) | 2016-12-15 |
CN102695804A (zh) | 2012-09-26 |
EP2507382A2 (en) | 2012-10-10 |
BR112012013034A2 (pt) | 2016-10-04 |
WO2011066497A2 (en) | 2011-06-03 |
EP2507382A4 (en) | 2016-06-08 |
MX2012006244A (es) | 2012-10-15 |
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