CA2782085A1 - Dp2 antagonist and uses thereof - Google Patents
Dp2 antagonist and uses thereof Download PDFInfo
- Publication number
- CA2782085A1 CA2782085A1 CA2782085A CA2782085A CA2782085A1 CA 2782085 A1 CA2782085 A1 CA 2782085A1 CA 2782085 A CA2782085 A CA 2782085A CA 2782085 A CA2782085 A CA 2782085A CA 2782085 A1 CA2782085 A1 CA 2782085A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- theta
- pharmaceutically acceptable
- acceptable salt
- pattern
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
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- Dermatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
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| US29280710P | 2010-01-06 | 2010-01-06 | |
| US61/292,807 | 2010-01-06 | ||
| PCT/US2011/020264 WO2011085033A2 (en) | 2010-01-06 | 2011-01-05 | Dp2 antagonist and uses thereof |
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| CA2782085A1 true CA2782085A1 (en) | 2011-07-14 |
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| US (1) | US9688624B2 (enExample) |
| EP (1) | EP2521713A4 (enExample) |
| JP (1) | JP2013516475A (enExample) |
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| CA2768492A1 (en) | 2009-07-31 | 2011-02-03 | Panmira Pharmaceuticals, Llc | Ophthalmic pharmaceutical compositions of dp2 receptor antagonists |
| SG11201402796SA (en) | 2011-12-16 | 2014-06-27 | Atopix Therapeutics Ltd | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| EA033143B1 (ru) * | 2012-03-21 | 2019-09-30 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Способ и применение селективного антагониста dp-2 по отношению к dp-1 для стимулирования роста волос |
| CN103830194A (zh) * | 2014-03-11 | 2014-06-04 | 熊妲妮 | 茚达特罗固体分散体及含有其的药物组合物 |
| US12059695B2 (en) * | 2021-09-16 | 2024-08-13 | Caterpillar Paving Products Inc. | Fluid spray system timing control |
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| US5239084A (en) | 1990-06-29 | 1993-08-24 | Hoffmann-La Roche Inc. | Substituted aminoalkyl biphenyl compounds |
| US5827868A (en) | 1991-10-07 | 1998-10-27 | E. R. Squibb & Sons, Inc. | Prostaglandin analogs |
| US5565485A (en) | 1993-03-19 | 1996-10-15 | Merck & Co., Inc. | Biphenyl compounds useful or endothelin antagonists |
| US5334598A (en) | 1993-03-19 | 1994-08-02 | Merck & Co., Inc. | Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives |
| US5391566A (en) | 1993-07-20 | 1995-02-21 | Merck & Co., Inc. | Benzimidazolinones substituted with phenoxyphenylacetic acid derivatives |
| DE19601782A1 (de) | 1996-01-19 | 1997-07-24 | Merck Patent Gmbh | Chinolin-2-(1H)one |
| CO4960662A1 (es) * | 1997-08-28 | 2000-09-25 | Novartis Ag | Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados |
| US6429213B1 (en) | 1998-06-17 | 2002-08-06 | Bristol Myers Squibb Pharma Co | Cyclic hydroxamic acids as metalloproteinase inhibitors |
| US6617351B1 (en) | 1998-07-31 | 2003-09-09 | Eli Lilly And Company | Amide, carbamate, and urea derivatives |
| EE200100558A (et) | 1999-04-28 | 2002-12-16 | Aventis Pharma Deutschland Gmbh | Triarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi raviotstarbeline kasutamine |
| DE19937537A1 (de) | 1999-08-09 | 2001-03-08 | Gruenenthal Gmbh | Substituierte 2-Dialkylaminoalkylbiphenyl-Derivate |
| US6884593B1 (en) | 1999-08-23 | 2005-04-26 | Bml, Inc. | Method of identifying properties of substance with respect to human prostaglandin D2 receptors |
| US20010047027A1 (en) | 2000-04-12 | 2001-11-29 | Marc Labelle | Prostaglandin D2 receptor antagonists |
| US6878522B2 (en) | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
| WO2002094830A2 (en) | 2001-05-23 | 2002-11-28 | Merck Frosst Canada & Co. | DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-a]-INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS |
| WO2003006011A1 (en) | 2001-07-09 | 2003-01-23 | Axys Pharmaceuticals, Inc. | 2-[5-(5-carbamimidoyl-1h-heteroaryl)-6-hydroxybiphenyl-3-yl]-succinic acid derivatives as factor viia inhibitors |
| AU2002336532C1 (en) * | 2001-09-14 | 2008-10-16 | Amgen, Inc | Linked biaryl compounds |
| DE60334015D1 (de) | 2002-10-30 | 2010-10-14 | Merck Frosst Canada Ltd | Pyridopyrrolizin- und pyridoindolizinderivate |
| JP2004182657A (ja) | 2002-12-04 | 2004-07-02 | Eisai Co Ltd | Ｈｄｌレベル上昇促進剤 |
| ES2401079T3 (es) | 2002-12-20 | 2013-04-16 | Amgen Inc. | Moduladores del asma y de la inflamación alérgica |
| ES2257616T3 (es) | 2003-04-25 | 2006-08-01 | Actimis Pharmaceuticals, Inc. | Derivados del acido pirimidinilacetico utiles para el tratamiento de enfermedades mediadas por crth2. |
| BRPI0415437A (pt) | 2003-10-14 | 2006-12-05 | Oxagen Ltd | composto, processo para a preparação e uso do mesmo, composição farmacêutica, processo para a preparação da mesma, e, produto |
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-
2011
- 2011-01-05 CA CA2782085A patent/CA2782085A1/en not_active Abandoned
- 2011-01-05 EP EP11732103.4A patent/EP2521713A4/en not_active Withdrawn
- 2011-01-05 EA EA201270653A patent/EA201270653A1/ru unknown
- 2011-01-05 MX MX2012007927A patent/MX2012007927A/es not_active Application Discontinuation
- 2011-01-05 CN CN2011800054059A patent/CN102812000A/zh active Pending
- 2011-01-05 WO PCT/US2011/020264 patent/WO2011085033A2/en not_active Ceased
- 2011-01-05 SG SG2012050043A patent/SG182398A1/en unknown
- 2011-01-05 PH PH1/2012/501349A patent/PH12012501349A1/en unknown
- 2011-01-05 AU AU2011203649A patent/AU2011203649A1/en not_active Abandoned
- 2011-01-05 US US13/519,292 patent/US9688624B2/en not_active Expired - Fee Related
- 2011-01-05 JP JP2012548102A patent/JP2013516475A/ja active Pending
- 2011-01-05 KR KR1020127019754A patent/KR20120115989A/ko not_active Withdrawn
-
2012
- 2012-05-24 IL IL219987A patent/IL219987A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120115989A (ko) | 2012-10-19 |
| WO2011085033A3 (en) | 2011-11-17 |
| EP2521713A2 (en) | 2012-11-14 |
| CN102812000A (zh) | 2012-12-05 |
| EP2521713A4 (en) | 2013-10-02 |
| EA201270653A1 (ru) | 2012-11-30 |
| US9688624B2 (en) | 2017-06-27 |
| MX2012007927A (es) | 2012-08-15 |
| SG182398A1 (en) | 2012-08-30 |
| PH12012501349A1 (en) | 2013-01-14 |
| IL219987A0 (en) | 2012-07-31 |
| US20130053444A1 (en) | 2013-02-28 |
| JP2013516475A (ja) | 2013-05-13 |
| AU2011203649A1 (en) | 2012-06-14 |
| WO2011085033A2 (en) | 2011-07-14 |
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| EEER | Examination request |
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| FZDE | Discontinued |
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