CA2776021C - Sulfonamides for the prevention of diabetes - Google Patents

Sulfonamides for the prevention of diabetes Download PDF

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Publication number
CA2776021C
CA2776021C CA2776021A CA2776021A CA2776021C CA 2776021 C CA2776021 C CA 2776021C CA 2776021 A CA2776021 A CA 2776021A CA 2776021 A CA2776021 A CA 2776021A CA 2776021 C CA2776021 C CA 2776021C
Authority
CA
Canada
Prior art keywords
diabetes
days
day
meraxin
reparixin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2776021A
Other languages
English (en)
French (fr)
Other versions
CA2776021A1 (en
Inventor
Lorenzo Piemonti
Luisa Daffonchio
Marcello Allegretti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dompe Farmaceutici SpA
Original Assignee
Dompe Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farmaceutici SpA filed Critical Dompe Farmaceutici SpA
Publication of CA2776021A1 publication Critical patent/CA2776021A1/en
Application granted granted Critical
Publication of CA2776021C publication Critical patent/CA2776021C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51Y being a hydrogen or a carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA2776021A 2009-10-06 2010-10-06 Sulfonamides for the prevention of diabetes Active CA2776021C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09172365.0 2009-10-06
EP09172365A EP2308485A1 (en) 2009-10-06 2009-10-06 Sulfonamides for the prevention of diabetes
PCT/EP2010/064920 WO2011042465A1 (en) 2009-10-06 2010-10-06 Sulfonamides for the prevention of diabetes

Publications (2)

Publication Number Publication Date
CA2776021A1 CA2776021A1 (en) 2011-04-14
CA2776021C true CA2776021C (en) 2017-08-01

Family

ID=41716341

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2776021A Active CA2776021C (en) 2009-10-06 2010-10-06 Sulfonamides for the prevention of diabetes

Country Status (24)

Country Link
US (2) US8846755B2 (https=)
EP (2) EP2308485A1 (https=)
JP (1) JP5745526B2 (https=)
KR (1) KR101737656B1 (https=)
CN (1) CN102639128B (https=)
AU (1) AU2010305384B2 (https=)
BR (1) BR112012007989B1 (https=)
CA (1) CA2776021C (https=)
CY (1) CY1117599T1 (https=)
DK (1) DK2485724T3 (https=)
EA (1) EA021788B1 (https=)
ES (1) ES2570463T3 (https=)
HR (1) HRP20160399T1 (https=)
HU (1) HUE028132T2 (https=)
IL (1) IL219038A (https=)
ME (1) ME02385B (https=)
MX (1) MX2012004087A (https=)
NZ (1) NZ599171A (https=)
PL (1) PL2485724T3 (https=)
RS (1) RS54693B1 (https=)
SI (1) SI2485724T1 (https=)
SM (1) SMT201600126B (https=)
WO (1) WO2011042465A1 (https=)
ZA (1) ZA201202462B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9844528B2 (en) * 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
EP3281937A1 (en) * 2016-08-09 2018-02-14 Dompé farmaceutici S.p.A. Sulfonamides as gpr40- and gpr120-agonists
US11291641B2 (en) 2016-10-03 2022-04-05 The Children's Medical Center Corporation Prevention and treatment of diabetic nephropathy
EP4686469A1 (en) 2024-07-31 2026-02-04 Dompé farmaceutici SpA Cxcl8 inhibitors for use in the treatment of diabetes-associated comorbidities

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303249B1 (it) * 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
ITMI20010206A1 (it) * 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz
US20040242498A1 (en) * 2003-02-27 2004-12-02 Collins Tassie L. CXCR3 antagonists
ATE444286T1 (de) 2004-03-23 2009-10-15 Dompe Pha R Ma Spa Res & Mfg 2-phenylpropionsäurederivate und diese enthaltende pharmazeutische zusammensetzung
PT1579859E (pt) 2004-03-25 2007-03-30 Dompe Pha R Ma Spa Res & Mfg Utilização de n-(2-aril-propionil)-sulfonamidas pata o tratamento de lesões da medula espinal
CN102088993A (zh) * 2008-03-20 2011-06-08 卡罗勒斯治疗公司 炎症的治疗方法
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes

Also Published As

Publication number Publication date
IL219038A (en) 2015-07-30
NZ599171A (en) 2014-03-28
HRP20160399T1 (hr) 2016-05-20
US8846755B2 (en) 2014-09-30
AU2010305384B2 (en) 2016-02-04
CN102639128A (zh) 2012-08-15
IL219038A0 (en) 2012-06-28
JP5745526B2 (ja) 2015-07-08
HUE028132T2 (en) 2016-11-28
KR20120083889A (ko) 2012-07-26
CY1117599T1 (el) 2017-04-26
US20130059908A1 (en) 2013-03-07
JP2013506703A (ja) 2013-02-28
DK2485724T3 (en) 2016-05-02
EA021788B1 (ru) 2015-08-31
PL2485724T3 (pl) 2016-07-29
BR112012007989B1 (pt) 2019-10-22
US9556115B2 (en) 2017-01-31
WO2011042465A1 (en) 2011-04-14
US20150011639A1 (en) 2015-01-08
KR101737656B1 (ko) 2017-05-18
ZA201202462B (en) 2013-06-26
AU2010305384A1 (en) 2012-04-26
RS54693B1 (sr) 2016-08-31
HK1174557A1 (en) 2013-06-14
EP2485724B1 (en) 2016-02-10
CA2776021A1 (en) 2011-04-14
SMT201600126B (it) 2016-07-01
ME02385B (me) 2016-09-20
EA201270512A1 (ru) 2012-11-30
SI2485724T1 (sl) 2018-12-31
MX2012004087A (es) 2012-08-23
ES2570463T3 (es) 2016-05-18
EP2308485A1 (en) 2011-04-13
CN102639128B (zh) 2014-02-26
EP2485724A1 (en) 2012-08-15

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