ES2570463T3 - Sulfonamidas para la prevención de la diabetes - Google Patents

Sulfonamidas para la prevención de la diabetes

Info

Publication number
ES2570463T3
ES2570463T3 ES10768898T ES10768898T ES2570463T3 ES 2570463 T3 ES2570463 T3 ES 2570463T3 ES 10768898 T ES10768898 T ES 10768898T ES 10768898 T ES10768898 T ES 10768898T ES 2570463 T3 ES2570463 T3 ES 2570463T3
Authority
ES
Spain
Prior art keywords
sulfonamides
diabetes prevention
diabetes
prevention
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10768898T
Other languages
English (en)
Inventor
Lorenzo Piemonti
Luisa Daffonchio
Marcello Allegretti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dompe Farmaceutici SpA
Original Assignee
Dompe Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farmaceutici SpA filed Critical Dompe Farmaceutici SpA
Application granted granted Critical
Publication of ES2570463T3 publication Critical patent/ES2570463T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Compuesto de fórmula I, o una sal farmacéuticamente aceptable del mismo:**Fórmula** en la que R se selecciona de 4-alquilo(C1-C6) lineal o ramificado, 4-trifluorometanosulfoniloxi y 3-benzoílo y R1 es alquilo(C1-C6) para uso en la prevención de la diabetes o en el retraso de la aparición y la evolución de diabetes.
ES10768898T 2009-10-06 2010-10-06 Sulfonamidas para la prevención de la diabetes Active ES2570463T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09172365A EP2308485A1 (en) 2009-10-06 2009-10-06 Sulfonamides for the prevention of diabetes
PCT/EP2010/064920 WO2011042465A1 (en) 2009-10-06 2010-10-06 Sulfonamides for the prevention of diabetes

Publications (1)

Publication Number Publication Date
ES2570463T3 true ES2570463T3 (es) 2016-05-18

Family

ID=41716341

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10768898T Active ES2570463T3 (es) 2009-10-06 2010-10-06 Sulfonamidas para la prevención de la diabetes

Country Status (25)

Country Link
US (2) US8846755B2 (es)
EP (2) EP2308485A1 (es)
JP (1) JP5745526B2 (es)
KR (1) KR101737656B1 (es)
CN (1) CN102639128B (es)
AU (1) AU2010305384B2 (es)
BR (1) BR112012007989B1 (es)
CA (1) CA2776021C (es)
CY (1) CY1117599T1 (es)
DK (1) DK2485724T3 (es)
EA (1) EA021788B1 (es)
ES (1) ES2570463T3 (es)
HK (1) HK1174557A1 (es)
HR (1) HRP20160399T1 (es)
HU (1) HUE028132T2 (es)
IL (1) IL219038A (es)
ME (1) ME02385B (es)
MX (1) MX2012004087A (es)
NZ (1) NZ599171A (es)
PL (1) PL2485724T3 (es)
RS (1) RS54693B1 (es)
SI (1) SI2485724T1 (es)
SM (1) SMT201600126B (es)
WO (1) WO2011042465A1 (es)
ZA (1) ZA201202462B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
EP3281937A1 (en) * 2016-08-09 2018-02-14 Dompé farmaceutici S.p.A. Sulfonamides as gpr40- and gpr120-agonists
AU2017339942B2 (en) * 2016-10-03 2023-06-29 Dompe Farmaceutici S.P.A. Prevention and treatment of diabetic nephropathy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303249B1 (it) 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
ITMI20010206A1 (it) 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz
US20040242498A1 (en) * 2003-02-27 2004-12-02 Collins Tassie L. CXCR3 antagonists
ME01763B (me) 2004-03-23 2010-10-31 Dompe Farm Spa Derivati 2-fenilpropionske kiseline i farmaceutske smeše koje ih sadrže
SI1579859T1 (sl) 2004-03-25 2007-04-30 Dompe Pha R Ma Spa Res & Mfg Uporaba n-(2-aril-propionil)-sulfonamidov za zdravljenje poskodbe hrbtnega mozga
US20110044988A1 (en) * 2008-03-20 2011-02-24 Carolus Therpeutics, Inc. Methods of treatment using anti-mif antibodies
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets

Also Published As

Publication number Publication date
CN102639128B (zh) 2014-02-26
HK1174557A1 (en) 2013-06-14
CY1117599T1 (el) 2017-04-26
US20130059908A1 (en) 2013-03-07
EA201270512A1 (ru) 2012-11-30
MX2012004087A (es) 2012-08-23
EP2308485A1 (en) 2011-04-13
CA2776021C (en) 2017-08-01
ME02385B (me) 2016-09-20
IL219038A0 (en) 2012-06-28
US8846755B2 (en) 2014-09-30
PL2485724T3 (pl) 2016-07-29
CN102639128A (zh) 2012-08-15
HUE028132T2 (en) 2016-11-28
ZA201202462B (en) 2013-06-26
WO2011042465A1 (en) 2011-04-14
KR101737656B1 (ko) 2017-05-18
SI2485724T1 (sl) 2018-12-31
BR112012007989B1 (pt) 2019-10-22
JP2013506703A (ja) 2013-02-28
EP2485724A1 (en) 2012-08-15
EP2485724B1 (en) 2016-02-10
JP5745526B2 (ja) 2015-07-08
US9556115B2 (en) 2017-01-31
NZ599171A (en) 2014-03-28
HRP20160399T1 (hr) 2016-05-20
IL219038A (en) 2015-07-30
RS54693B1 (en) 2016-08-31
SMT201600126B (it) 2016-07-01
CA2776021A1 (en) 2011-04-14
US20150011639A1 (en) 2015-01-08
DK2485724T3 (en) 2016-05-02
KR20120083889A (ko) 2012-07-26
EA021788B1 (ru) 2015-08-31
AU2010305384B2 (en) 2016-02-04
AU2010305384A1 (en) 2012-04-26

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