CA2760705A1 - Pyrazolopyridines - Google Patents

Info

Publication number

CA2760705A1

CA2760705A1 CA2760705A CA2760705A CA2760705A1 CA 2760705 A1 CA2760705 A1 CA 2760705A1 CA 2760705 A CA2760705 A CA 2760705A CA 2760705 A CA2760705 A CA 2760705A CA 2760705 A1 CA2760705 A1 CA 2760705A1

Authority

CA

Canada

Prior art keywords

independently

compound

halogen

optionally

aliphatic

Prior art date

2009-05-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Abandoned

Links

• Espacenet
• Global Dossier
• CIPO
• Discuss

• 150000005229 pyrazolopyridines Chemical class 0.000 title description 3
• 150000001875 compounds Chemical class 0.000 claims abstract description 243
• 238000000034 method Methods 0.000 claims abstract description 82
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• 239000000203 mixture Substances 0.000 claims abstract description 69
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• 102000001253 Protein Kinase Human genes 0.000 claims abstract description 39
• 108060006633 protein kinase Proteins 0.000 claims abstract description 39
• 125000001931 aliphatic group Chemical group 0.000 claims description 69
• 229910052736 halogen Inorganic materials 0.000 claims description 62
• 229910052739 hydrogen Inorganic materials 0.000 claims description 59
• 150000002367 halogens Chemical class 0.000 claims description 53
• 229910052757 nitrogen Inorganic materials 0.000 claims description 49
• 230000001404 mediated effect Effects 0.000 claims description 48
• 150000003839 salts Chemical class 0.000 claims description 42
• 125000004093 cyano group Chemical group *C#N 0.000 claims description 38
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• 125000003118 aryl group Chemical group 0.000 claims description 37
• 229920006395 saturated elastomer Polymers 0.000 claims description 36
• 229910052799 carbon Inorganic materials 0.000 claims description 28
• 125000000623 heterocyclic group Chemical group 0.000 claims description 28
• OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 25
• 125000002837 carbocyclic group Chemical group 0.000 claims description 22
• 125000005843 halogen group Chemical group 0.000 claims description 22
• 125000001072 heteroaryl group Chemical group 0.000 claims description 22
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 22
• 125000002950 monocyclic group Chemical group 0.000 claims description 21
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• 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims description 19
• 229910052717 sulfur Inorganic materials 0.000 claims description 19
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• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 4
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