CA2756071A1 - Rapid antemortem detection of infectious agents - Google Patents
Rapid antemortem detection of infectious agents Download PDFInfo
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- CA2756071A1 CA2756071A1 CA2756071A CA2756071A CA2756071A1 CA 2756071 A1 CA2756071 A1 CA 2756071A1 CA 2756071 A CA2756071 A CA 2756071A CA 2756071 A CA2756071 A CA 2756071A CA 2756071 A1 CA2756071 A1 CA 2756071A1
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- 238000011886 postmortem examination Methods 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000002331 protein detection Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000008707 rearrangement Effects 0.000 description 1
- XLXOKMFKGASILN-UHFFFAOYSA-N rhodamine red-X Chemical group C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=C(S(=O)(=O)NCCCCCC(O)=O)C=C1S([O-])(=O)=O XLXOKMFKGASILN-UHFFFAOYSA-N 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 238000011896 sensitive detection Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 210000004989 spleen cell Anatomy 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
- 229960001600 xylazine Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2872—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against prion molecules, e.g. CD230
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2828—Prion diseases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21126509P | 2009-03-25 | 2009-03-25 | |
| US21126409P | 2009-03-25 | 2009-03-25 | |
| US61/211,264 | 2009-03-25 | ||
| US61/211,265 | 2009-03-25 | ||
| PCT/US2010/028698 WO2010111514A1 (en) | 2009-03-25 | 2010-03-25 | Rapid antemortem detection of infectious agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2756071A1 true CA2756071A1 (en) | 2010-09-30 |
Family
ID=42781515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2756071A Abandoned CA2756071A1 (en) | 2009-03-25 | 2010-03-25 | Rapid antemortem detection of infectious agents |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100261195A1 (enExample) |
| EP (1) | EP2411051A4 (enExample) |
| JP (1) | JP2012522222A (enExample) |
| CN (1) | CN102365096A (enExample) |
| AU (1) | AU2010229864A1 (enExample) |
| CA (1) | CA2756071A1 (enExample) |
| IL (1) | IL215196A0 (enExample) |
| WO (1) | WO2010111514A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102362179A (zh) | 2009-03-25 | 2012-02-22 | 洛斯阿拉莫斯国家安全有限责任公司 | 用于荧光光谱测定的光纤光学组件 |
| WO2011081887A1 (en) * | 2009-12-15 | 2011-07-07 | Los Alamos National Security, Llc | High throughput fiber optical assembly for fluorescence spectrometry |
| US20130288389A1 (en) * | 2011-01-18 | 2013-10-31 | Prionics Ag | Methods for amplification and detection of prions |
| CN116688912A (zh) * | 2023-07-06 | 2023-09-05 | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 一种高通量筛选方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4702598A (en) * | 1985-02-25 | 1987-10-27 | Research Corporation | Flow cytometer |
| US5714388A (en) * | 1996-08-14 | 1998-02-03 | Bayer Corporation | Apparatus and method for detecting chemiluminescent light |
| US6124597A (en) * | 1997-07-07 | 2000-09-26 | Cedars-Sinai Medical Center | Method and devices for laser induced fluorescence attenuation spectroscopy |
| US6982431B2 (en) * | 1998-08-31 | 2006-01-03 | Molecular Devices Corporation | Sample analysis systems |
| US6608671B2 (en) * | 1998-07-17 | 2003-08-19 | Vertex Pharmaceuticals (San Diego) Llc | Detector and screening device for ion channels |
| US7041807B1 (en) * | 1999-06-23 | 2006-05-09 | Caprion Pharmaceuticals, Inc. | Antibodies to a YYX epitope of a mammalian prion protein |
| NZ516240A (en) * | 1999-06-23 | 2005-11-25 | Caprion Pharmaceuticals Inc | Prion protein peptides and uses thereof |
| US6538735B1 (en) * | 2000-02-25 | 2003-03-25 | Packard Instrument Company | Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells |
| US7079252B1 (en) * | 2000-06-01 | 2006-07-18 | Lifescan, Inc. | Dual beam FTIR methods and devices for use in analyte detection in samples of low transmissivity |
| US6870165B2 (en) * | 2001-10-19 | 2005-03-22 | Biocal Technology, Inc. | Multi-color multiplexed analysis in a bio-separation system |
| US7647092B2 (en) * | 2002-04-05 | 2010-01-12 | Massachusetts Institute Of Technology | Systems and methods for spectroscopy of biological tissue |
| US20040073120A1 (en) * | 2002-04-05 | 2004-04-15 | Massachusetts Institute Of Technology | Systems and methods for spectroscopy of biological tissue |
| US8497134B2 (en) * | 2004-08-19 | 2013-07-30 | Blood Cell Storage, Inc. | Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices |
| JP2008537155A (ja) * | 2005-04-20 | 2008-09-11 | ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム | 自動化タンパク質異常折り畳みの周期的増幅によるプリオンの超高感度検出 |
| FR2884920B1 (fr) * | 2005-04-21 | 2007-08-10 | Horiba Abx Sa Sa | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
| US7847941B2 (en) * | 2005-12-07 | 2010-12-07 | Los Alamos National Security, Llc | Fiber optical assembly for fluorescence spectrometry |
-
2010
- 2010-03-25 CA CA2756071A patent/CA2756071A1/en not_active Abandoned
- 2010-03-25 JP JP2012502259A patent/JP2012522222A/ja not_active Withdrawn
- 2010-03-25 WO PCT/US2010/028698 patent/WO2010111514A1/en not_active Ceased
- 2010-03-25 EP EP10756857A patent/EP2411051A4/en not_active Withdrawn
- 2010-03-25 CN CN2010800137555A patent/CN102365096A/zh active Pending
- 2010-03-25 AU AU2010229864A patent/AU2010229864A1/en not_active Abandoned
- 2010-03-25 US US12/731,776 patent/US20100261195A1/en not_active Abandoned
-
2011
- 2011-09-18 IL IL215196A patent/IL215196A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20100261195A1 (en) | 2010-10-14 |
| WO2010111514A9 (en) | 2010-12-02 |
| EP2411051A1 (en) | 2012-02-01 |
| AU2010229864A1 (en) | 2011-10-27 |
| EP2411051A4 (en) | 2012-09-19 |
| IL215196A0 (en) | 2011-12-29 |
| JP2012522222A (ja) | 2012-09-20 |
| CN102365096A (zh) | 2012-02-29 |
| WO2010111514A1 (en) | 2010-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20150325 |