CA2756071A1 - Rapid antemortem detection of infectious agents - Google Patents

Rapid antemortem detection of infectious agents Download PDF

Info

Publication number
CA2756071A1
CA2756071A1 CA2756071A CA2756071A CA2756071A1 CA 2756071 A1 CA2756071 A1 CA 2756071A1 CA 2756071 A CA2756071 A CA 2756071A CA 2756071 A CA2756071 A CA 2756071A CA 2756071 A1 CA2756071 A1 CA 2756071A1
Authority
CA
Canada
Prior art keywords
prp
prps
detection
sample
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2756071A
Other languages
English (en)
French (fr)
Inventor
Richard Rubenstein
Martin S. Piltch
Perry Clayton Gray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Los Alamos National Security LLC
Research Foundation of the State University of New York
Original Assignee
Los Alamos National Security LLC
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Los Alamos National Security LLC, Research Foundation of the State University of New York filed Critical Los Alamos National Security LLC
Publication of CA2756071A1 publication Critical patent/CA2756071A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2872—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against prion molecules, e.g. CD230
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2756071A 2009-03-25 2010-03-25 Rapid antemortem detection of infectious agents Abandoned CA2756071A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21126409P 2009-03-25 2009-03-25
US21126509P 2009-03-25 2009-03-25
US61/211,264 2009-03-25
US61/211,265 2009-03-25
PCT/US2010/028698 WO2010111514A1 (en) 2009-03-25 2010-03-25 Rapid antemortem detection of infectious agents

Publications (1)

Publication Number Publication Date
CA2756071A1 true CA2756071A1 (en) 2010-09-30

Family

ID=42781515

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2756071A Abandoned CA2756071A1 (en) 2009-03-25 2010-03-25 Rapid antemortem detection of infectious agents

Country Status (8)

Country Link
US (1) US20100261195A1 (enExample)
EP (1) EP2411051A4 (enExample)
JP (1) JP2012522222A (enExample)
CN (1) CN102365096A (enExample)
AU (1) AU2010229864A1 (enExample)
CA (1) CA2756071A1 (enExample)
IL (1) IL215196A0 (enExample)
WO (1) WO2010111514A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9110024B2 (en) 2009-03-25 2015-08-18 Los Alamos National Security, Llc Fiber optical asssembly for fluorescence spectrometry
US20110140001A1 (en) * 2009-12-15 2011-06-16 Los Alamos National Security, Llc High throughput fiber optical assembly for fluorescence spectrometry
EP2666020A1 (en) * 2011-01-18 2013-11-27 The United States of America, as represented by The Secretary, Department of Health and Human Services Methods for amplification and detection of prions
WO2022029732A1 (en) 2020-08-07 2022-02-10 Vital Biosciences Inc. Kinetic modulation for magnetic analyte detection
CN116688912A (zh) * 2023-07-06 2023-09-05 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 一种高通量筛选方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4702598A (en) * 1985-02-25 1987-10-27 Research Corporation Flow cytometer
US5714388A (en) * 1996-08-14 1998-02-03 Bayer Corporation Apparatus and method for detecting chemiluminescent light
US6124597A (en) * 1997-07-07 2000-09-26 Cedars-Sinai Medical Center Method and devices for laser induced fluorescence attenuation spectroscopy
US6982431B2 (en) * 1998-08-31 2006-01-03 Molecular Devices Corporation Sample analysis systems
US6608671B2 (en) * 1998-07-17 2003-08-19 Vertex Pharmaceuticals (San Diego) Llc Detector and screening device for ion channels
US7041807B1 (en) * 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
MXPA01013186A (es) * 1999-06-23 2002-08-12 Caprion Pharmaceuticals Inc Peptidos de la proteina prion y sus usos.
US6538735B1 (en) * 2000-02-25 2003-03-25 Packard Instrument Company Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells
US7079252B1 (en) * 2000-06-01 2006-07-18 Lifescan, Inc. Dual beam FTIR methods and devices for use in analyte detection in samples of low transmissivity
US6870165B2 (en) * 2001-10-19 2005-03-22 Biocal Technology, Inc. Multi-color multiplexed analysis in a bio-separation system
US20040073120A1 (en) * 2002-04-05 2004-04-15 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US7647092B2 (en) * 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US8497134B2 (en) * 2004-08-19 2013-07-30 Blood Cell Storage, Inc. Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices
US20060263767A1 (en) * 2005-04-20 2006-11-23 The Board Of Regents Of The University Of Texas System Ultrasensitive detection of prions by automated protein misfolding cyclic amplification
FR2884920B1 (fr) * 2005-04-21 2007-08-10 Horiba Abx Sa Sa Dispositif et procede d'analyse multiparametrique d'elements microscopiques
US7847941B2 (en) * 2005-12-07 2010-12-07 Los Alamos National Security, Llc Fiber optical assembly for fluorescence spectrometry

Also Published As

Publication number Publication date
EP2411051A1 (en) 2012-02-01
WO2010111514A1 (en) 2010-09-30
EP2411051A4 (en) 2012-09-19
IL215196A0 (en) 2011-12-29
JP2012522222A (ja) 2012-09-20
US20100261195A1 (en) 2010-10-14
CN102365096A (zh) 2012-02-29
WO2010111514A9 (en) 2010-12-02
AU2010229864A1 (en) 2011-10-27

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20150325