CA2753713A1 - Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer - Google Patents

Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer Download PDF

Info

Publication number
CA2753713A1
CA2753713A1 CA2753713A CA2753713A CA2753713A1 CA 2753713 A1 CA2753713 A1 CA 2753713A1 CA 2753713 A CA2753713 A CA 2753713A CA 2753713 A CA2753713 A CA 2753713A CA 2753713 A1 CA2753713 A1 CA 2753713A1
Authority
CA
Canada
Prior art keywords
glycodelin
monoclonal antibody
seq
antibody
ovarian cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2753713A
Other languages
English (en)
French (fr)
Inventor
Robert L. Cheek
Eric P. Dixon
Timothy J. Fischer
John W. Groelke
Steven L. Knapp
Stephen G. Simkins
Clark M. Whitehead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TriPath Imaging Inc
Original Assignee
TriPath Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TriPath Imaging Inc filed Critical TriPath Imaging Inc
Publication of CA2753713A1 publication Critical patent/CA2753713A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2753713A 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer Abandoned CA2753713A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15815909P 2009-03-06 2009-03-06
US61/158,159 2009-03-06
PCT/US2010/026319 WO2010102177A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Publications (1)

Publication Number Publication Date
CA2753713A1 true CA2753713A1 (en) 2010-09-10

Family

ID=42101610

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2753713A Abandoned CA2753713A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Country Status (6)

Country Link
US (2) US8252904B2 (enrdf_load_stackoverflow)
EP (1) EP2403875A1 (enrdf_load_stackoverflow)
JP (1) JP2012524521A (enrdf_load_stackoverflow)
AU (1) AU2010221188A1 (enrdf_load_stackoverflow)
CA (1) CA2753713A1 (enrdf_load_stackoverflow)
WO (1) WO2010102177A1 (enrdf_load_stackoverflow)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201312117A (zh) * 2011-07-28 2013-03-16 Univ Pennsylvania 用以診斷與漿液相關之腫瘤細胞的症狀及特性的方法及試劑
AU2012296613B2 (en) 2011-08-15 2016-05-12 Amplimmune, Inc. Anti-B7-H4 antibodies and their uses
BR112015014063A2 (pt) 2012-12-19 2018-10-30 Amplimmune Inc anticorpos anti-b7-h4 humano e seus usos.
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201604468D0 (en) * 2016-03-16 2016-04-27 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
CN106053836A (zh) * 2016-06-30 2016-10-26 深圳市亚辉龙生物科技股份有限公司 抗子宫内膜抗体化学发光免疫检测试剂盒及其制备方法
CN106199012A (zh) * 2016-06-30 2016-12-07 深圳市亚辉龙生物科技股份有限公司 抑制素b化学发光免疫检测试剂盒及其制备方法
JP7211604B2 (ja) * 2017-12-05 2023-01-24 国立大学法人金沢大学 膠芽腫マーカー及びその使用
US20190346457A1 (en) 2018-03-13 2019-11-14 Government Of The Unted States, As Represented By The Secretary Of The Army Assays and methods for detection and targeted treatment of hydrosalpinx
WO2020046793A1 (en) 2018-08-27 2020-03-05 Regeneron Pharmaceuticals, Inc. Use of raman spectroscopy in downstream purification
CN116496394B (zh) * 2022-01-26 2024-07-23 东莞市朋志生物科技有限公司 抗s100蛋白的抗体、检测s100蛋白的试剂和试剂盒

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP1997891A1 (en) 1988-09-02 2008-12-03 Dyax Corporation Generation and selection of recombinant varied binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
GB9022543D0 (en) 1990-10-17 1990-11-28 Wellcome Found Antibody production
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
EP0575485A1 (en) 1991-03-01 1993-12-29 Dyax Corp. Process for the development of binding mini-proteins
US5658727A (en) 1991-04-10 1997-08-19 The Scripps Research Institute Heterodimeric receptor libraries using phagemids
CA2064544A1 (en) * 1991-06-28 1992-12-29 Anthony E. Bolton Immune cell proliferation inhibitors
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
DE614989T1 (de) 1993-02-17 1995-09-28 Morphosys Proteinoptimierung Verfahren für in vivo Selektion von Ligandenbindende Proteine.
US5830698A (en) 1997-03-14 1998-11-03 Idec Pharmaceuticals Corporation Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
DE19807389C2 (de) * 1998-02-21 2000-08-17 Max Delbrueck Centrum Monoklonale Antikörper gegen Glycodelin A, Verfahren zu ihrer Herstellung und ihre Verwendung
US20020058292A1 (en) * 2000-12-08 2002-05-16 Dillon Davin C. Ovarian tumor antigen and methods of use therefor
AU2002258518A1 (en) * 2001-03-14 2002-09-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
KR100882249B1 (ko) 2004-03-24 2009-02-06 트리패스 이미징, 인코포레이티드 자궁경부 질환의 검사 방법 및 조성물
US7595380B2 (en) 2005-04-27 2009-09-29 Tripath Imaging, Inc. Monoclonal antibodies and methods for their use in the detection of cervical disease
AU2007211085A1 (en) * 2006-01-27 2007-08-09 Tripath Imaging, Inc. Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor
KR20100015438A (ko) * 2007-03-09 2010-02-12 트리패스 이미징, 인코포레이티드 Ｈｅ4 모노클로날 항체 및 이의 사용 방법
US20090087849A1 (en) * 2007-09-06 2009-04-02 Tripath Imaging, Inc. Nucleic acid-based methods and compositions for the detection of ovarian cancer

Also Published As

Publication number Publication date
JP2012524521A (ja) 2012-10-18
US20130022998A1 (en) 2013-01-24
US8476033B2 (en) 2013-07-02
AU2010221188A1 (en) 2011-10-20
US8252904B2 (en) 2012-08-28
US20100227343A1 (en) 2010-09-09
EP2403875A1 (en) 2012-01-11
WO2010102177A1 (en) 2010-09-10

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FZDE Dead

Effective date: 20150305