CA2745946A1 - Cysteine-free efficient technetium (tc) or rhenium (re) chelating peptide tags and their use - Google Patents

Cysteine-free efficient technetium (tc) or rhenium (re) chelating peptide tags and their use Download PDF

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Publication number
CA2745946A1
CA2745946A1 CA2745946A CA2745946A CA2745946A1 CA 2745946 A1 CA2745946 A1 CA 2745946A1 CA 2745946 A CA2745946 A CA 2745946A CA 2745946 A CA2745946 A CA 2745946A CA 2745946 A1 CA2745946 A1 CA 2745946A1
Authority
CA
Canada
Prior art keywords
seq
tco
peptide
protein
ubi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2745946A
Other languages
English (en)
French (fr)
Inventor
Loic Le Clainche
Alain Lecoq
Sophie Zinn-Justin
Robert Thai
Michel Masella
Philippe Cuniasse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Publication of CA2745946A1 publication Critical patent/CA2745946A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2745946A 2008-12-30 2009-12-28 Cysteine-free efficient technetium (tc) or rhenium (re) chelating peptide tags and their use Abandoned CA2745946A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08291257.7 2008-12-30
EP08291257A EP2204377A1 (en) 2008-12-30 2008-12-30 Cysteine-free technetium (tc) or rhenium (re) chelating peptide tags and their use
PCT/IB2009/007971 WO2010076654A2 (en) 2008-12-30 2009-12-28 CYSTEINE-FREE EFFICIENT TECHNETIUM (Tc) OR RHENIUM (Re) CHELATING PEPTIDE TAGS AND THEIR USE

Publications (1)

Publication Number Publication Date
CA2745946A1 true CA2745946A1 (en) 2010-07-08

Family

ID=40578262

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2745946A Abandoned CA2745946A1 (en) 2008-12-30 2009-12-28 Cysteine-free efficient technetium (tc) or rhenium (re) chelating peptide tags and their use

Country Status (5)

Country Link
US (1) US9234001B2 (enExample)
EP (2) EP2204377A1 (enExample)
JP (1) JP5756758B2 (enExample)
CA (1) CA2745946A1 (enExample)
WO (1) WO2010076654A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2949463B1 (fr) 2009-08-26 2011-09-16 Commissariat Energie Atomique Inhibiteurs de mmp

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421735A (en) * 1980-04-17 1983-12-20 The Massachusetts General Hospital Radiolabeled diagnostic compositions and method for making the same
US5128119A (en) * 1989-06-12 1992-07-07 Immunomedics, Inc. Methods for technetium/rhenium labeling of f(ab1)2 fragments
NL1006164C2 (nl) * 1997-05-29 1998-12-01 Univ Leiden Antimicrobiële peptiden.

Also Published As

Publication number Publication date
JP5756758B2 (ja) 2015-07-29
EP2382229B1 (en) 2013-07-24
US9234001B2 (en) 2016-01-12
EP2204377A1 (en) 2010-07-07
WO2010076654A3 (en) 2010-12-16
WO2010076654A2 (en) 2010-07-08
EP2382229A2 (en) 2011-11-02
JP2012513980A (ja) 2012-06-21
US20110318827A1 (en) 2011-12-29

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20141212

FZDE Discontinued

Effective date: 20170523