CA2738151C - Eye drop with difluprednate for macular edema treatment - Google Patents
Eye drop with difluprednate for macular edema treatment Download PDFInfo
- Publication number
- CA2738151C CA2738151C CA2738151A CA2738151A CA2738151C CA 2738151 C CA2738151 C CA 2738151C CA 2738151 A CA2738151 A CA 2738151A CA 2738151 A CA2738151 A CA 2738151A CA 2738151 C CA2738151 C CA 2738151C
- Authority
- CA
- Canada
- Prior art keywords
- eye drop
- administration
- difluprednate
- weeks
- per day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000003889 eye drop Substances 0.000 title claims abstract description 130
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- 229960004875 difluprednate Drugs 0.000 title claims abstract description 82
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Classifications
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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Landscapes
- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009-165924 | 2009-07-14 | ||
| JP2009165924 | 2009-07-14 | ||
| PCT/JP2010/062289 WO2011007893A1 (en) | 2009-07-14 | 2010-07-14 | Eye drop with difluprednate for macular edema treatment |
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| JP5902100B2 (ja) * | 2011-01-14 | 2016-04-13 | 株式会社エス・ディー・エス バイオテック | ４−（３−ブチニル）アミノピリミジン誘導体を含む農園芸用有害生物防除剤組成物 |
| US20140018402A1 (en) * | 2011-03-30 | 2014-01-16 | Catholic University Industry Academic Cooperation Foundation | Pharmaceutical composition for preventing or treating macular degeneration |
| CN103130857A (zh) * | 2011-11-30 | 2013-06-05 | 天津金耀集团有限公司 | 二氟泼尼酯ⅱ晶型及其制备方法 |
| CN103130859B (zh) * | 2011-11-30 | 2015-12-02 | 天津金耀集团有限公司 | 二氟泼尼酯晶型i及其制备方法 |
| KR20150119315A (ko) * | 2013-02-15 | 2015-10-23 | 센주 세이야꾸 가부시키가이샤 | 아연을 함유하는 디플루프레드네이트 유액 조성물 |
| GB2516561B (en) * | 2013-03-15 | 2016-03-09 | Aerpio Therapeutics Inc | Compositions, formulations and methods for treating ocular diseases |
| WO2015197594A2 (de) | 2014-06-23 | 2015-12-30 | Schott Ag | Elektrisches speichersystem enthaltend ein scheibenförmiges diskretes element, scheibenförmiges diskretes element sowie verfahren zu dessen herstellung und dessen verwendung |
| JP2018505515A (ja) | 2014-12-01 | 2018-02-22 | ショット アクチエンゲゼルシャフトＳｃｈｏｔｔ ＡＧ | シート状の独立した部材を有する蓄電システム、独立したシート状の部材、その製造方法、およびその使用 |
| EP4566638A3 (en) * | 2015-05-29 | 2025-08-27 | Allergan, Inc. | Implant for treatment of an ocular condition |
| RU2661621C2 (ru) * | 2016-12-19 | 2018-07-17 | Александр Николаевич Епихин | Способ пролонгации и усиления терапевтического эффекта действия ингибиторов ангиогенеза при лечении неоваскулярных форм макулярных дегенераций |
| CN108014172A (zh) * | 2017-12-29 | 2018-05-11 | 广州仁恒医药科技股份有限公司 | 一种含有二氟泼尼酯的药物组合物及其制备方法 |
| KR20210012346A (ko) | 2019-07-25 | 2021-02-03 | 심낙범 | 미세먼지 눈꺼풀 세정스틱 |
| US20210100856A1 (en) * | 2019-09-11 | 2021-04-08 | Adverum Biotechnologies, Inc. | Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept |
| WO2021050649A1 (en) * | 2019-09-11 | 2021-03-18 | Adverum Biotechnologies, Inc. | Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept |
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| AU684115B2 (en) | 1993-12-27 | 1997-12-04 | Mitsubishi Chemical Corporation | Ophthalmic suspension containing diflupredonate |
| US6114319A (en) | 1997-05-14 | 2000-09-05 | Senju Pharmaceutical Co., Ltd. | Compositions containing difluprednate |
| JP3410364B2 (ja) | 1997-05-14 | 2003-05-26 | 千寿製薬株式会社 | ジフルプレドナート含有組成物 |
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| US20070049568A1 (en) | 2005-08-25 | 2007-03-01 | Psivida Inc. | Control of induced elevated intraocular pressure |
| US20090105245A1 (en) * | 2006-12-21 | 2009-04-23 | Bingaman David P | Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor |
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| ES2405779T3 (es) | 2013-06-03 |
| US20110190250A1 (en) | 2011-08-04 |
| EP2340014B1 (en) | 2013-04-24 |
| KR20120040683A (ko) | 2012-04-27 |
| CN103705524A (zh) | 2014-04-09 |
| CN102170865A (zh) | 2011-08-31 |
| RU2011125640A (ru) | 2013-08-20 |
| CN107569494A (zh) | 2018-01-12 |
| EP2340014A1 (en) | 2011-07-06 |
| US20180133153A1 (en) | 2018-05-17 |
| US9949926B2 (en) | 2018-04-24 |
| WO2011007893A1 (en) | 2011-01-20 |
| JP2012533517A (ja) | 2012-12-27 |
| KR101689847B1 (ko) | 2016-12-26 |
| PL2340014T3 (pl) | 2013-09-30 |
| RU2572707C2 (ru) | 2016-01-20 |
| BRPI1005380A2 (pt) | 2016-02-10 |
| US10092514B2 (en) | 2018-10-09 |
| US20150190340A1 (en) | 2015-07-09 |
| MX2011005043A (es) | 2011-06-01 |
| TW201105363A (en) | 2011-02-16 |
| JP5579079B2 (ja) | 2014-08-27 |
| CA2738151A1 (en) | 2011-01-20 |
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