CA2736970A1 - Derives de pyrimidinone pour utilisation en tant que medicaments - Google Patents
Derives de pyrimidinone pour utilisation en tant que medicaments Download PDFInfo
- Publication number
- CA2736970A1 CA2736970A1 CA2736970A CA2736970A CA2736970A1 CA 2736970 A1 CA2736970 A1 CA 2736970A1 CA 2736970 A CA2736970 A CA 2736970A CA 2736970 A CA2736970 A CA 2736970A CA 2736970 A1 CA2736970 A1 CA 2736970A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- formula
- optionally substituted
- substituents selected
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13654008P | 2008-09-12 | 2008-09-12 | |
| US61/136,540 | 2008-09-12 | ||
| US19383708P | 2008-12-30 | 2008-12-30 | |
| US61/193,837 | 2008-12-30 | ||
| PCT/GB2009/002169 WO2010029299A1 (fr) | 2008-09-12 | 2009-09-10 | Dérivés de pyrimidinone pour utilisation en tant que médicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2736970A1 true CA2736970A1 (fr) | 2010-03-18 |
Family
ID=41381867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2736970A Abandoned CA2736970A1 (fr) | 2008-09-12 | 2009-09-10 | Derives de pyrimidinone pour utilisation en tant que medicaments |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA2736970A1 (fr) |
| WO (1) | WO2010029299A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012116440A1 (fr) * | 2011-03-03 | 2012-09-07 | Zalicus Pharmaceuticals Ltd. | Inhibiteurs de type benzimidazole du canal sodique |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5627574B2 (ja) | 2008-06-03 | 2014-11-19 | インターミューン， インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| WO2011114103A1 (fr) * | 2010-03-18 | 2011-09-22 | Biolipox Ab | Pyrimidinones pour usage médicamenteux |
| AU2012382373A1 (en) | 2012-06-12 | 2014-12-11 | Abbvie Inc. | Pyridinone and pyridazinone derivatives |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| BR122023004130B1 (pt) | 2013-06-27 | 2023-12-12 | Pfizer Inc | Compostos heteroaromáticos, composição farmacêutica e uso dos referidos compostos no tratamento de distúrbios mediados ou associados a dopamina d1 |
| US9828348B2 (en) | 2013-11-08 | 2017-11-28 | Purdue Pharma L.P. | Benzimidazole derivatives and use thereof |
| RU2692485C2 (ru) | 2014-04-02 | 2019-06-25 | Интермьюн, Инк. | Противофиброзные пиридиноны |
| WO2017089347A1 (fr) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Procédés et compositions pharmaceutiques pour le traitement de mélanomes résistant aux inhibiteurs de braf |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| ES2962605T3 (es) | 2018-02-26 | 2024-03-20 | Gilead Sciences Inc | Compuestos de pirrolizina sustituidos como inhibidores de la replicación del VHB |
| MX2022004874A (es) | 2019-10-25 | 2022-05-13 | Gilead Sciences Inc | Compuestos de modulacion de glp-1r. |
| CA3168543A1 (fr) | 2020-01-29 | 2021-08-05 | Gilead Sciences, Inc. | Composes modulateurs de glp-1r |
| US11851419B2 (en) | 2020-11-20 | 2023-12-26 | Gilead Sciences, Inc. | GLP-1R modulating compounds |
| WO2022192428A1 (fr) | 2021-03-11 | 2022-09-15 | Gilead Sciences, Inc. | Composés modulateurs de glp-1r |
| KR20230173708A (ko) | 2021-04-21 | 2023-12-27 | 길리애드 사이언시즈, 인코포레이티드 | 카르복시-벤즈이미다졸 glp-1r 조절 화합물 |
| WO2024038090A1 (fr) | 2022-08-18 | 2024-02-22 | Mitodicure Gmbh | Utilisation de composés de benzofurane et de benzoxazole substitués pour le traitement et la prévention de maladies associées à la fatigue chronique, à l'épuisement et/ou à l'intolérance à l'effort |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5814651A (en) * | 1992-12-02 | 1998-09-29 | Pfizer Inc. | Catechol diethers as selective PDEIV inhibitors |
| AU767585B2 (en) * | 2000-01-25 | 2003-11-20 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| GB0722769D0 (en) * | 2007-11-21 | 2008-01-02 | Biolipox Ab | New compounds |
-
2009
- 2009-09-10 CA CA2736970A patent/CA2736970A1/fr not_active Abandoned
- 2009-09-10 WO PCT/GB2009/002169 patent/WO2010029299A1/fr active Application Filing
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012116440A1 (fr) * | 2011-03-03 | 2012-09-07 | Zalicus Pharmaceuticals Ltd. | Inhibiteurs de type benzimidazole du canal sodique |
| US9688615B2 (en) | 2011-03-03 | 2017-06-27 | Degiacomo, Interim Trustee, Mark G. | Benzimidazole inhibitors of the sodium channel |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010029299A1 (fr) | 2010-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20130910 |