CA2723403A1 - Estrogenic extracts for use in treating vaginal and vulvar atrophy - Google Patents
Estrogenic extracts for use in treating vaginal and vulvar atrophy Download PDFInfo
- Publication number
- CA2723403A1 CA2723403A1 CA2723403A CA2723403A CA2723403A1 CA 2723403 A1 CA2723403 A1 CA 2723403A1 CA 2723403 A CA2723403 A CA 2723403A CA 2723403 A CA2723403 A CA 2723403A CA 2723403 A1 CA2723403 A1 CA 2723403A1
- Authority
- CA
- Canada
- Prior art keywords
- extract
- composition
- cell
- mixture
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5092508P | 2008-05-06 | 2008-05-06 | |
| US61/050,925 | 2008-05-06 | ||
| PCT/US2009/042915 WO2009137534A2 (en) | 2008-05-06 | 2009-05-05 | Estrogenic extracts for use in treating vaginal and vulvar atrophy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2723403A1 true CA2723403A1 (en) | 2009-11-12 |
Family
ID=41265360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2723403A Abandoned CA2723403A1 (en) | 2008-05-06 | 2009-05-05 | Estrogenic extracts for use in treating vaginal and vulvar atrophy |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090304825A1 (enExample) |
| EP (1) | EP2310024A4 (enExample) |
| JP (1) | JP2011519947A (enExample) |
| AU (1) | AU2009244315A1 (enExample) |
| CA (1) | CA2723403A1 (enExample) |
| WO (1) | WO2009137534A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7482029B2 (en) | 2005-04-01 | 2009-01-27 | Bionovo, Inc. | Composition for treatment of menopause |
| US20080319051A1 (en) * | 2007-06-22 | 2008-12-25 | Bionovo, Inc. | Liquiritigenin and derivatives as selective estrogen receptor beta agonists |
| US20090042818A1 (en) * | 2007-06-22 | 2009-02-12 | Bionovo, Inc. | Liquiritigenin and Derivatives as Selective Estrogen Receptor Beta Agonists |
| AU2008285325A1 (en) * | 2007-08-08 | 2009-02-12 | Bionovo, Inc. | Extracts of Ligustrum lucidum and uses thereof |
| JP2010539086A (ja) * | 2007-09-07 | 2010-12-16 | バイオノボ・インコーポレーテッド | マメ科ファミリーのクズのエストロゲン性抽出物およびその使用 |
| EP2190292A4 (en) * | 2007-09-07 | 2012-12-26 | Bionovo Inc | ESTROGENWIRKSAME EXTRACTS OF SCUTTELARIA BARBATA D. DON OF THE FAMILY LABIATAE AND ITS USES |
| CA2698732A1 (en) * | 2007-09-07 | 2009-03-12 | Bionovo, Inc. | Estrogenic extracts of astragalus membranaceus fisch.bge.var.mongolicus bge. of the leguminosae family and uses thereof |
| CA2706326A1 (en) * | 2007-11-19 | 2009-05-28 | Bionovo, Inc. | Scutellaria barbata extract and combinations for the treatment of cancer |
| JP2011503237A (ja) * | 2007-11-19 | 2011-01-27 | バイオノボ・インコーポレーテッド | Scutellariabarbatad.donの精製抽出物を作製するためのプロセス |
| WO2009067553A1 (en) * | 2007-11-19 | 2009-05-28 | Bionovo, Inc. | Anti-cancer therapy with an extract of scutellaria barbata |
| CA2706313A1 (en) * | 2007-11-19 | 2009-05-28 | Bionovo, Inc. | Methods of detecting and treatment of cancers using scuttelaria barbata extract |
| EP2276480A4 (en) * | 2008-04-14 | 2011-08-10 | Bionovo Inc | CALYCOSINE AND ITS ANALOGUE FOR THE TREATMENT OF ESTROGEN RECEPTOR-BETA-MEDIATED ILLNESSES |
| US20090311349A1 (en) * | 2008-06-05 | 2009-12-17 | Bionovo, Inc., A Delaware Corporation | Method of quantification of multiple bioactives from botanical compositions |
| EP2303249A4 (en) * | 2008-06-06 | 2012-05-30 | Bionovo Inc | ANTHRAQUINONES AND ANALOGS FROM RHEUM PALMATUM FOR THE TREATMENT OF MEDIA CONDITIONS BY THE STROGEN BETA RECEPTOR |
| EP2323641A4 (en) * | 2008-06-13 | 2012-06-20 | Bionovo Inc | NYASOL AND ANALOGUE THEREOF FOR THE TREATMENT OF ESTROGEN RECEPTOR-BETA-MEDIATED ILLNESSES |
| EP2340027A4 (en) * | 2008-09-03 | 2012-04-04 | Bionovo Inc | METHOD AND COMPOSITIONS FOR THE TREATMENT OF CANCER |
| US20130014771A1 (en) * | 2011-01-13 | 2013-01-17 | R. J. Reynolds Tobacco Company | Tobacco-derived components and materials |
| CN105037447B (zh) * | 2015-06-17 | 2018-01-16 | 广东药科大学 | 牛膝糖聚合物及其制备方法和用途 |
| CN104987340B (zh) * | 2015-07-07 | 2017-06-23 | 江苏省中国科学院植物研究所 | 碱蓬黄酮a及其制备方法和用途 |
| KR102168418B1 (ko) * | 2019-07-29 | 2020-10-21 | 김덕호 | 황칠나무, 황기 및, 두릅나무 복합 추출물을 포함하는 여성 청결제 조성물 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2616328B1 (fr) * | 1987-06-12 | 1990-03-02 | Moet Hennessy Rech | Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un extrait de murier, ou au moins une flavone, en particulier une kuwanone et composition pharmaceutique, notamment dermatologique, a activite depigmentante, ou anti-inflammatoire, ou cosmetique, l'incorporant |
| JPH01175942A (ja) * | 1987-12-28 | 1989-07-12 | Sanyo Kokusaku Pulp Co Ltd | 抗ウイルス性医薬用組成物 |
| JPH0725761A (ja) * | 1993-07-09 | 1995-01-27 | Kureha Chem Ind Co Ltd | 軟骨保護剤 |
| US5874084A (en) * | 1996-07-19 | 1999-02-23 | Yng-Wong; Quing Non | Using complex herbal formulations to treat hot flashes |
| EP0923938A4 (en) * | 1997-03-21 | 2004-01-02 | Shiseido Co Ltd | immunostimulants |
| MC2441A1 (fr) * | 1997-07-31 | 1998-03-11 | Exsymol Sa | Composition cosmétique utile notamment pour le blanchiment de la peau et agent inhibiteur de la mélanogénèse comprenant une telle composition cosmétique |
| FR2784294B1 (fr) * | 1998-10-12 | 2000-11-17 | Oreal | Composition cosmetique et/ou dermatologique renfermant au moins un extrait de murier, au moins un extrait de scutellaire et au moins un derive d'acide salicylique |
| US6304825B1 (en) * | 1999-01-19 | 2001-10-16 | Xerox Corporation | Rotary encoder error compensation system and method for photoreceptor surface motion sensing and control |
| FR2791573B1 (fr) * | 1999-03-30 | 2003-04-11 | Pf Medicament | Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate |
| CN1247240C (zh) * | 1999-04-01 | 2006-03-29 | G&W澳大利亚股份有限公司 | 用于治疗过敏性鼻炎的草药组合物及其用途 |
| US20020031559A1 (en) * | 2000-03-08 | 2002-03-14 | Liang Kin C. | Herbal suppositories |
| DE10031650A1 (de) * | 2000-06-29 | 2002-01-17 | Schwabe Willmar Gmbh & Co | Verwendung von Extrakten aus Sophora flavescens oder Sophora subprostrata zur Prophylaxe und Therapie von Krankheitszuständen, die durch einen Mangel an Östrogenen oder durch andere hormonelle Dysregulationen verursacht werden |
| US6238707B1 (en) * | 2000-10-11 | 2001-05-29 | Zhang Chun | Herbal hormone balance composition |
| JP2002234835A (ja) * | 2001-02-09 | 2002-08-23 | Sangaku Renkei Kiko Kyushu:Kk | 血管新生阻害剤 |
| US6551627B1 (en) * | 2001-05-03 | 2003-04-22 | Holomed Pharmaceuticals, Ltd. | Medicinal herbal compounds for the prevention and treatment of diabetes |
| KR100456981B1 (ko) * | 2001-07-14 | 2004-11-10 | (주) 메드빌 | 식물추출물을 포함하는 골다공증 예방 또는 치료용 조성물및 그 제조 방법 |
| US6855344B2 (en) * | 2001-07-17 | 2005-02-15 | Integrated Chinese Medicine Holdings, Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| KR20030027208A (ko) * | 2001-09-14 | 2003-04-07 | 주식회사 바이오딕스 | 생약을 함유하는 관절염 치료용 조성물 및 그 제조방법 |
| JP2003095971A (ja) * | 2001-09-27 | 2003-04-03 | National Institute Of Health & Nutrition | 骨粗鬆症治療剤または組成物 |
| US6750248B2 (en) * | 2001-11-09 | 2004-06-15 | National University Of Singapore | Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof |
| US20050032882A1 (en) * | 2002-03-06 | 2005-02-10 | Sophie Chen | Botanical extract compositions and methods of use |
| AU2002952453A0 (en) * | 2002-11-01 | 2002-11-21 | Novogen Research Pty Ltd | Aminated isoflavonoid derivatives and uses thereof |
| CA2520532A1 (en) * | 2003-03-28 | 2004-10-14 | Nihon University | Polynucleotide encoding 2-hydroxyisoflavanone dehydratase and use thereof |
| US20070122501A1 (en) * | 2003-06-27 | 2007-05-31 | Hong Kong University Of Science And Technology | Formulations containing astragalus extracts and uses thereof |
| US8173177B2 (en) * | 2003-09-08 | 2012-05-08 | Genyous Biomed International Inc. | Compositions of botanical extracts for cancer therapy |
| US20050196409A1 (en) * | 2003-09-24 | 2005-09-08 | James Dao | Compositions of botanical extracts for treating malignancy-associated changes |
| WO2006053415A1 (en) * | 2004-11-18 | 2006-05-26 | Biopharmacopae Design International Inc. | Plant extract having matrix metalloprotease inhibiting activity and dermatological uses thereof |
| US20050118290A1 (en) * | 2003-12-02 | 2005-06-02 | University Of Singapore | Compositions and method for treatment of steroid/nuclear receptor-mediated diseases |
| US20050208159A1 (en) * | 2004-03-16 | 2005-09-22 | Kang Kyung S | Phytoestrogenic composition comprising an extract of chinese licorice root, liquiritin or isoliquiritin |
| WO2005107747A2 (en) * | 2004-05-06 | 2005-11-17 | Bioresponse, Llc | Diindolymethane formulations for the treatment of leiomyomas |
| CA2585561C (en) * | 2004-11-05 | 2018-07-17 | Genomic Health, Inc. | Esr1, pgr, bcl2 and scube2 group score as indicators of breast cancer prognosis and prediction of treatment response |
| KR100589050B1 (ko) * | 2004-11-23 | 2006-06-14 | 인하대학교 산학협력단 | 황기 추출물 및 그로부터 분리한 이소플라보노이드계화합물을 유효성분으로 하는 관절염 예방 및 치료용 조성물 |
| JP2008523065A (ja) * | 2004-12-09 | 2008-07-03 | メルク エンド カムパニー インコーポレーテッド | エストロゲン受容体モジュレーター |
| AU2005316824B2 (en) * | 2004-12-17 | 2012-05-31 | Bionovo, Inc. | Method of using extracts of epimedium species |
| JP2008524222A (ja) * | 2004-12-17 | 2008-07-10 | バイオノボ・インコーポレーテッド | Morusalbaのエストロゲン様抽出物およびその使用 |
| TW200621273A (en) * | 2004-12-21 | 2006-07-01 | Golden Biotechnology Corp | A composition for effectively inhibiting prostate cancer cell growth and hypertrophy of the prostate, and a preparing method thereof |
| US7482029B2 (en) * | 2005-04-01 | 2009-01-27 | Bionovo, Inc. | Composition for treatment of menopause |
| WO2006138275A2 (en) * | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US7700136B2 (en) * | 2005-11-14 | 2010-04-20 | Bionovo, Inc. | Scutellaria barbata extract for the treatment of cancer |
| ES2612377T3 (es) * | 2005-12-21 | 2017-05-16 | Janssen Pharmaceutica N.V. | Triazolopiridazinas como moduladores de tirosina cinasas |
| CN100475253C (zh) * | 2006-02-22 | 2009-04-08 | 陈耀明 | 一种治疗不孕症、月经不调、痛经、内分泌失调及骨质疏松的药物 |
| KR100760384B1 (ko) * | 2006-02-22 | 2007-09-19 | 경희대학교 산학협력단 | 황기 추출물을 포함하는 혈관형성 촉진 및 골유합 효과를갖는 골절의 예방 및 치료용 조성물 |
| CN100488525C (zh) * | 2006-08-04 | 2009-05-20 | 北京化工大学 | 一种治疗女性更年期综合症的药物及制备方法 |
| US7381432B2 (en) * | 2006-09-19 | 2008-06-03 | Jose Angel Olalde | Menopause disorder synergistic phyto-nutraceutical composition |
| CN1961744A (zh) * | 2006-12-08 | 2007-05-16 | 富天桂 | 一种保健食品 |
| US20080319051A1 (en) * | 2007-06-22 | 2008-12-25 | Bionovo, Inc. | Liquiritigenin and derivatives as selective estrogen receptor beta agonists |
| US20090042818A1 (en) * | 2007-06-22 | 2009-02-12 | Bionovo, Inc. | Liquiritigenin and Derivatives as Selective Estrogen Receptor Beta Agonists |
| AU2008285325A1 (en) * | 2007-08-08 | 2009-02-12 | Bionovo, Inc. | Extracts of Ligustrum lucidum and uses thereof |
| JP2010539086A (ja) * | 2007-09-07 | 2010-12-16 | バイオノボ・インコーポレーテッド | マメ科ファミリーのクズのエストロゲン性抽出物およびその使用 |
| AU2008296176A1 (en) * | 2007-09-07 | 2009-03-12 | Bionovo, Inc. | Estrogenic extracts of Asparagus conchinchinensis (Lour.) Merr of the Liliaceae Family and uses thereof |
| CA2698732A1 (en) * | 2007-09-07 | 2009-03-12 | Bionovo, Inc. | Estrogenic extracts of astragalus membranaceus fisch.bge.var.mongolicus bge. of the leguminosae family and uses thereof |
| EP2276480A4 (en) * | 2008-04-14 | 2011-08-10 | Bionovo Inc | CALYCOSINE AND ITS ANALOGUE FOR THE TREATMENT OF ESTROGEN RECEPTOR-BETA-MEDIATED ILLNESSES |
| US20090311349A1 (en) * | 2008-06-05 | 2009-12-17 | Bionovo, Inc., A Delaware Corporation | Method of quantification of multiple bioactives from botanical compositions |
| EP2303249A4 (en) * | 2008-06-06 | 2012-05-30 | Bionovo Inc | ANTHRAQUINONES AND ANALOGS FROM RHEUM PALMATUM FOR THE TREATMENT OF MEDIA CONDITIONS BY THE STROGEN BETA RECEPTOR |
| EP2323641A4 (en) * | 2008-06-13 | 2012-06-20 | Bionovo Inc | NYASOL AND ANALOGUE THEREOF FOR THE TREATMENT OF ESTROGEN RECEPTOR-BETA-MEDIATED ILLNESSES |
-
2009
- 2009-05-05 WO PCT/US2009/042915 patent/WO2009137534A2/en not_active Ceased
- 2009-05-05 AU AU2009244315A patent/AU2009244315A1/en not_active Abandoned
- 2009-05-05 CA CA2723403A patent/CA2723403A1/en not_active Abandoned
- 2009-05-05 US US12/436,020 patent/US20090304825A1/en not_active Abandoned
- 2009-05-05 EP EP09743520A patent/EP2310024A4/en not_active Withdrawn
- 2009-05-05 JP JP2011508616A patent/JP2011519947A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011519947A (ja) | 2011-07-14 |
| AU2009244315A1 (en) | 2009-11-12 |
| EP2310024A2 (en) | 2011-04-20 |
| WO2009137534A2 (en) | 2009-11-12 |
| EP2310024A4 (en) | 2012-07-25 |
| WO2009137534A3 (en) | 2010-02-18 |
| US20090304825A1 (en) | 2009-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20140203 |