CA2719824A1 - Methods and compositions for treating schizophrenia using antipsychotic combination therapy - Google Patents
Methods and compositions for treating schizophrenia using antipsychotic combination therapy Download PDFInfo
- Publication number
- CA2719824A1 CA2719824A1 CA2719824A CA2719824A CA2719824A1 CA 2719824 A1 CA2719824 A1 CA 2719824A1 CA 2719824 A CA2719824 A CA 2719824A CA 2719824 A CA2719824 A CA 2719824A CA 2719824 A1 CA2719824 A1 CA 2719824A1
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- CA
- Canada
- Prior art keywords
- antipsychotic
- schizophrenia
- dimebon
- risperidone
- combination therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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| RU2007129568/15A RU2508096C2 (ru) | 2007-08-01 | 2007-08-01 | Способы и композиции для лечения шизофрении с использованием нейролептической комбинированной терапии |
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| RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
| RU2544856C2 (ru) * | 2008-01-25 | 2015-03-20 | Сергей Олегович Бачурин | НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| BRPI0906245A2 (pt) | 2008-03-24 | 2015-06-30 | Medivation Technologies Inc | Composto, método para tratar um distúrbio cognitivo, psicótico, mediado por neurotransmissor ou um distúrbio neuronal em indivíduo, uso de um composto, composição farmacêutica e kit |
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| EP2348847A4 (en) | 2008-10-31 | 2012-05-23 | Medivation Technologies Inc | AZEPINO [4, 5-B] INDOLE AND USE PROCESS |
| SG173639A1 (en) | 2009-02-11 | 2011-09-29 | Sunovion Pharmaceuticals Inc | Histamine h3 inverse agonists and antagonists and methods of use thereof |
| CN103145707B (zh) * | 2009-04-10 | 2016-05-25 | 中国人民解放军军事医学科学院毒物药物研究所 | 氢化吡啶[4,3-b]吲哚类化合物的制备方法 |
| CN102480956B (zh) | 2009-04-29 | 2015-04-08 | 梅迪维新技术公司 | 吡啶并[4,3-b]吲哚类和使用方法 |
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| WO2011103485A1 (en) * | 2010-02-18 | 2011-08-25 | Medivation Technologies, Inc. | Fused tetracyclic pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS229067B1 (en) * | 1981-08-20 | 1984-04-16 | Svorad Stolc | Medicinal preparation with antiarhythmic and supporting effect applied with hypoxia,and method of preparing active substance thereof |
| US4672117A (en) * | 1985-09-16 | 1987-06-09 | American Home Products Corporation | Antipsychotic gamma-carbolines |
| US5300645A (en) * | 1993-04-14 | 1994-04-05 | Eli Lilly And Company | Tetrahydro-pyrido-indole |
| US5631265A (en) * | 1994-03-11 | 1997-05-20 | Eli Lilly And Company | 8-substituted tetrahydro-beta-carbolines |
| RU2140417C1 (ru) * | 1995-10-17 | 1999-10-27 | Институт физиологически активных веществ РАН | Производные гидрированных пиридо(4,3-b)индолов, способы их получения, фармацевтическая композиция и способ лечения |
| TW470745B (en) * | 1996-05-23 | 2002-01-01 | Janssen Pharmaceutica Nv | Hexahydro-pyrido[4,3-b]indole derivatives |
| BR0211608A (pt) * | 2001-08-08 | 2006-04-04 | Upjohn Co | 1h-pirido[4,3-b]indóis terapêuticos |
| WO2005120463A1 (en) * | 2004-06-09 | 2005-12-22 | Ranbaxy Laboratories Limited | Rapidly disintegrating tablets of risperidone |
| WO2007041697A2 (en) * | 2005-10-04 | 2007-04-12 | Medivation, Inc. | Hydrogenated pyrido-indole compounds for the treatment of huntington ' s disease |
| US20070112017A1 (en) * | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| RU2338537C2 (ru) * | 2006-01-25 | 2008-11-20 | Сергей Олегович Бачурин | СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ |
| JP2010528016A (ja) * | 2007-05-25 | 2010-08-19 | メディベーション ニューロロジー， インコーポレイテッド | 細胞を刺激するための方法および組成物 |
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2008
- 2008-08-01 EP EP08826868A patent/EP2175724A4/en not_active Withdrawn
- 2008-08-01 MX MX2010001218A patent/MX2010001218A/es not_active Application Discontinuation
- 2008-08-01 BR BRPI0815850-9A2A patent/BRPI0815850A2/pt not_active IP Right Cessation
- 2008-08-01 JP JP2010519954A patent/JP2010535220A/ja active Pending
- 2008-08-01 US US12/671,679 patent/US20110269777A1/en not_active Abandoned
- 2008-08-01 AU AU2008282742A patent/AU2008282742A1/en not_active Abandoned
- 2008-08-01 CA CA2719824A patent/CA2719824A1/en not_active Abandoned
- 2008-08-01 CN CN200880107277A patent/CN101842010A/zh active Pending
- 2008-08-01 KR KR1020107004429A patent/KR20100054812A/ko not_active Withdrawn
- 2008-08-01 WO PCT/US2008/009357 patent/WO2009017836A1/en not_active Ceased
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| JP2010535220A (ja) | 2010-11-18 |
| EP2175724A1 (en) | 2010-04-21 |
| CN101842010A (zh) | 2010-09-22 |
| BRPI0815850A2 (pt) | 2014-10-07 |
| WO2009017836A1 (en) | 2009-02-05 |
| MX2010001218A (es) | 2010-04-07 |
| AU2008282742A1 (en) | 2009-02-05 |
| US20110269777A1 (en) | 2011-11-03 |
| EP2175724A4 (en) | 2010-09-15 |
| KR20100054812A (ko) | 2010-05-25 |
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