CA2717348C - .delta.4 desaturase and its use in making polyunsaturated fatty acids - Google Patents

.delta.4 desaturase and its use in making polyunsaturated fatty acids Download PDF

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Publication number
CA2717348C
CA2717348C CA2717348A CA2717348A CA2717348C CA 2717348 C CA2717348 C CA 2717348C CA 2717348 A CA2717348 A CA 2717348A CA 2717348 A CA2717348 A CA 2717348A CA 2717348 C CA2717348 C CA 2717348C
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CA
Canada
Prior art keywords
seq
desaturase
host cell
acid
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2717348A
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English (en)
French (fr)
Other versions
CA2717348A1 (en
Inventor
Zhixiong Xue
Quinn Qun Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of CA2717348A1 publication Critical patent/CA2717348A1/en
Application granted granted Critical
Publication of CA2717348C publication Critical patent/CA2717348C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
CA2717348A 2008-04-02 2009-04-01 .delta.4 desaturase and its use in making polyunsaturated fatty acids Expired - Fee Related CA2717348C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4171608P 2008-04-02 2008-04-02
US61/041,716 2008-04-02
PCT/US2009/039062 WO2009124101A1 (en) 2008-04-02 2009-04-01 Δ4 desaturase and its use in making polyunsaturated fatty acids

Publications (2)

Publication Number Publication Date
CA2717348A1 CA2717348A1 (en) 2009-10-08
CA2717348C true CA2717348C (en) 2017-10-31

Family

ID=40775376

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2717348A Expired - Fee Related CA2717348C (en) 2008-04-02 2009-04-01 .delta.4 desaturase and its use in making polyunsaturated fatty acids

Country Status (8)

Country Link
US (1) US8119784B2 (https=)
EP (1) EP2259674B1 (https=)
JP (1) JP5572620B2 (https=)
CN (1) CN101980595B (https=)
AU (1) AU2009231744B2 (https=)
CA (1) CA2717348C (https=)
DK (1) DK2259674T3 (https=)
WO (1) WO2009124101A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110059496A1 (en) * 2003-06-25 2011-03-10 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
CA3056110C (en) 2004-04-22 2020-07-14 Surinder Pal Singh Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
DK1756280T3 (en) 2004-04-22 2015-02-02 Commw Scient Ind Res Org SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS
US9062321B2 (en) * 2004-12-01 2015-06-23 Arizona Board Of Regents On Behalf Of Arizona State University Codon-optimized polynucleotides encoding human butyrylcholinesterase and plant expression systems therof
CN101578363A (zh) 2006-08-29 2009-11-11 联邦科学技术研究组织 脂肪酸的合成
NO2358882T3 (https=) 2008-11-18 2017-12-23
US9493520B2 (en) * 2009-07-17 2016-11-15 Basf Plant Science Company Gmbh Fatty acid desaturases and elongases and uses thereof
PL2861059T3 (pl) 2012-06-15 2017-10-31 Commw Scient Ind Res Org Wytwarzanie długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach roślinnych
CA2879154A1 (en) 2012-08-03 2014-02-06 Basf Plant Science Company Gmbh Novel enzymes, enzyme components and uses thereof
CA2923296A1 (en) 2013-10-25 2015-04-30 Pioneer Hi-Bred International, Inc. Stem canker tolerant soybeans and methods of use
BR112016014174B1 (pt) 2013-12-18 2022-03-15 BASF Agro B.V. Método de controle de vegetação indesejada e método de produção de uma célula vegetal transgênica
NZ721036A (en) * 2013-12-18 2023-07-28 Grains Res & Dev Corp Lipid comprising long chain polyunsaturated fatty acids
CN103820402B (zh) * 2014-01-29 2016-02-10 佳木斯大学 一种来源于小眼虫的δ4脂肪酸去饱和酶及其应用
SG10201909391QA (en) * 2014-06-27 2019-11-28 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
PH12016502586B1 (en) 2014-06-27 2023-07-19 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
CA3004914A1 (en) 2016-02-05 2017-08-10 Pioneer Hi-Bred International, Inc. Genetic loci associated with brown stem rot resistance in soybean and methods of use
KR102054761B1 (ko) * 2018-03-06 2019-12-12 대한민국(농촌진흥청장) 갈고리 흰오징어 유래 델타-4 불포화효소 유전자
KR102864657B1 (ko) * 2022-08-26 2025-09-25 한국생명공학연구원 신규한 유트렙티엘라 속 균주 및 이를 이용한 지방산의 생산방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101845446B (zh) * 2000-09-28 2016-01-20 生物源食物及科学公司 脂肪酸去饱和酶家族成员fad4、fad5、fad5-2和fad6及它们的应用
US7045683B2 (en) 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
MXPA05010571A (es) 2003-04-08 2005-11-23 Basf Plant Science Gmbh Delta-4-desaturasas a partir de euglena gracilis, que expresan plantas y aceites que comprenden pufa
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados

Also Published As

Publication number Publication date
CA2717348A1 (en) 2009-10-08
JP2011516067A (ja) 2011-05-26
AU2009231744B2 (en) 2014-05-08
DK2259674T3 (da) 2014-08-04
AU2009231744A1 (en) 2009-10-08
JP5572620B2 (ja) 2014-08-13
CN101980595B (zh) 2013-03-13
EP2259674B1 (en) 2014-05-07
CN101980595A (zh) 2011-02-23
US8119784B2 (en) 2012-02-21
US20090253188A1 (en) 2009-10-08
EP2259674A1 (en) 2010-12-15
WO2009124101A1 (en) 2009-10-08

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Legal Events

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EEER Examination request

Effective date: 20140325

MKLA Lapsed

Effective date: 20220301

MKLA Lapsed

Effective date: 20200831