CA2717348C - .delta.4 desaturase and its use in making polyunsaturated fatty acids - Google Patents

.delta.4 desaturase and its use in making polyunsaturated fatty acids Download PDF

Info

Publication number
CA2717348C
CA2717348C CA2717348A CA2717348A CA2717348C CA 2717348 C CA2717348 C CA 2717348C CA 2717348 A CA2717348 A CA 2717348A CA 2717348 A CA2717348 A CA 2717348A CA 2717348 C CA2717348 C CA 2717348C
Authority
CA
Canada
Prior art keywords
seq
desaturase
host cell
acid
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2717348A
Other languages
English (en)
French (fr)
Other versions
CA2717348A1 (en
Inventor
Zhixiong Xue
Quinn Qun Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of CA2717348A1 publication Critical patent/CA2717348A1/en
Application granted granted Critical
Publication of CA2717348C publication Critical patent/CA2717348C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CA2717348A 2008-04-02 2009-04-01 .delta.4 desaturase and its use in making polyunsaturated fatty acids Expired - Fee Related CA2717348C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4171608P 2008-04-02 2008-04-02
US61/041,716 2008-04-02
PCT/US2009/039062 WO2009124101A1 (en) 2008-04-02 2009-04-01 Δ4 desaturase and its use in making polyunsaturated fatty acids

Publications (2)

Publication Number Publication Date
CA2717348A1 CA2717348A1 (en) 2009-10-08
CA2717348C true CA2717348C (en) 2017-10-31

Family

ID=40775376

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2717348A Expired - Fee Related CA2717348C (en) 2008-04-02 2009-04-01 .delta.4 desaturase and its use in making polyunsaturated fatty acids

Country Status (8)

Country Link
US (1) US8119784B2 (enExample)
EP (1) EP2259674B1 (enExample)
JP (1) JP5572620B2 (enExample)
CN (1) CN101980595B (enExample)
AU (1) AU2009231744B2 (enExample)
CA (1) CA2717348C (enExample)
DK (1) DK2259674T3 (enExample)
WO (1) WO2009124101A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110059496A1 (en) * 2003-06-25 2011-03-10 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
PL1756280T3 (pl) 2004-04-22 2015-04-30 Commw Scient Ind Res Org Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
US9062321B2 (en) * 2004-12-01 2015-06-23 Arizona Board Of Regents On Behalf Of Arizona State University Codon-optimized polynucleotides encoding human butyrylcholinesterase and plant expression systems therof
BRPI0716075A2 (pt) 2006-08-29 2013-08-06 Commw Scient Ind Res Org sÍntese de Ácidos graxos
CA3015426C (en) 2008-11-18 2020-01-14 Commonwealth Scientific And Industrial Research Organisation Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases
US9493520B2 (en) * 2009-07-17 2016-11-15 Basf Plant Science Company Gmbh Fatty acid desaturases and elongases and uses thereof
HUE033766T2 (en) 2012-06-15 2018-01-29 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
AU2013298113A1 (en) 2012-08-03 2015-01-29 Basf Plant Science Company Gmbh Novel enzymes, enzyme components and uses thereof
US20160272997A1 (en) 2013-10-25 2016-09-22 Pioneer Hi-Bred International, Inc. Stem canker tolerant soybeans and methods of use
CA2933002C (en) 2013-12-18 2023-08-15 BASF Agro B.V. Plants having an increased tolerance to protoporphyrinogen oxidase (ppo) herbicides
EA037817B1 (ru) * 2013-12-18 2021-05-25 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты
CN103820402B (zh) * 2014-01-29 2016-02-10 佳木斯大学 一种来源于小眼虫的δ4脂肪酸去饱和酶及其应用
CA2953008C (en) * 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
CN117305343A (zh) * 2014-06-27 2023-12-29 联邦科学技术研究组织 包含二十二碳五烯酸的提取的植物脂质
US11096344B2 (en) 2016-02-05 2021-08-24 Pioneer Hi-Bred International, Inc. Genetic loci associated with brown stem rot resistance in soybean and methods of use
KR102054761B1 (ko) * 2018-03-06 2019-12-12 대한민국(농촌진흥청장) 갈고리 흰오징어 유래 델타-4 불포화효소 유전자
KR102864657B1 (ko) * 2022-08-26 2025-09-25 한국생명공학연구원 신규한 유트렙티엘라 속 균주 및 이를 이용한 지방산의 생산방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2343106T3 (es) * 2000-09-28 2010-07-23 BIORIGINAL FOOD & SCIENCE CORP. Fad4, fad5, fad5-2 y fad6, miembros de la familia de desaturasas de acidos grasos y usos de los mismos.
US7045683B2 (en) 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
JP4732333B2 (ja) 2003-04-08 2011-07-27 ビーエーエスエフ プラント サイエンス ゲーエムベーハー ミドリムシ(Euglenagracilis)由来のΔ−4−デサチュラーゼを発現する植物およびPUFA含有油
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados

Also Published As

Publication number Publication date
CN101980595B (zh) 2013-03-13
DK2259674T3 (da) 2014-08-04
US20090253188A1 (en) 2009-10-08
WO2009124101A1 (en) 2009-10-08
JP5572620B2 (ja) 2014-08-13
AU2009231744B2 (en) 2014-05-08
US8119784B2 (en) 2012-02-21
JP2011516067A (ja) 2011-05-26
EP2259674B1 (en) 2014-05-07
EP2259674A1 (en) 2010-12-15
AU2009231744A1 (en) 2009-10-08
CA2717348A1 (en) 2009-10-08
CN101980595A (zh) 2011-02-23

Similar Documents

Publication Publication Date Title
CA2717348C (en) .delta.4 desaturase and its use in making polyunsaturated fatty acids
US8241884B2 (en) Δ17 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) Δ 5 desaturase and its use in making polyunsaturated fatty acids
US7695950B2 (en) Δ5 desaturase and its use in making polyunsaturated fatty acids
US8367383B2 (en) Mutant Δ-5 desaturases mutated in the heme-binding motif (HPGG) and their use in making polyunsaturated fatty acids
US7465793B2 (en) Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids
US8148121B2 (en) Δ6 desaturases and their use in making polyunsaturated fatty acids
US20080153141A1 (en) Delta - 9 desaturase and its use in making polyunsaturated fatty acids

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140325

MKLA Lapsed

Effective date: 20220301

MKLA Lapsed

Effective date: 20200831