CA2710546A1 - Narcotic emulsion formulations for treatment of surgical pain - Google Patents
Narcotic emulsion formulations for treatment of surgical pain Download PDFInfo
- Publication number
- CA2710546A1 CA2710546A1 CA2710546A CA2710546A CA2710546A1 CA 2710546 A1 CA2710546 A1 CA 2710546A1 CA 2710546 A CA2710546 A CA 2710546A CA 2710546 A CA2710546 A CA 2710546A CA 2710546 A1 CA2710546 A1 CA 2710546A1
- Authority
- CA
- Canada
- Prior art keywords
- emulsion
- fentanyl
- emulsion formulation
- pain
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5357108P | 2008-05-15 | 2008-05-15 | |
| US61/053,571 | 2008-05-15 | ||
| US12/424,382 US20090286832A1 (en) | 2008-05-15 | 2009-04-15 | Narcotic emulsion formulations for treatment of surgical pain |
| US12/424,382 | 2009-04-15 | ||
| PCT/US2009/041991 WO2009140059A2 (en) | 2008-05-15 | 2009-04-28 | Narcotic emulsion formulations for treatment of surgical pain |
Publications (1)
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|---|---|
| CA2710546A1 true CA2710546A1 (en) | 2009-11-19 |
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| CA2710546A Abandoned CA2710546A1 (en) | 2008-05-15 | 2009-04-28 | Narcotic emulsion formulations for treatment of surgical pain |
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| Country | Link |
|---|---|
| US (1) | US20090286832A1 (https=) |
| EP (1) | EP2276440A4 (https=) |
| JP (2) | JP5689053B2 (https=) |
| KR (1) | KR101361479B1 (https=) |
| CN (1) | CN101938963A (https=) |
| AR (1) | AR071779A1 (https=) |
| AU (1) | AU2009246713B2 (https=) |
| BR (1) | BRPI0907224A2 (https=) |
| CA (1) | CA2710546A1 (https=) |
| EA (1) | EA201000991A1 (https=) |
| IL (1) | IL209145A0 (https=) |
| MX (1) | MX2010007698A (https=) |
| NZ (1) | NZ586461A (https=) |
| TW (2) | TWI413531B (https=) |
| WO (1) | WO2009140059A2 (https=) |
| ZA (1) | ZA201004392B (https=) |
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| US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
| EP2400838B1 (en) * | 2009-02-26 | 2016-05-11 | Teikoku Pharma USA, Inc. | Narcotic emulsion formulations for treatment of cancer pain |
| JP6081240B2 (ja) * | 2013-03-13 | 2017-02-15 | テルモ株式会社 | レミフェンタニル注射液剤 |
| EP3192509B1 (en) | 2014-09-12 | 2021-03-31 | Terumo Kabushiki Kaisha | Remifentanil injection |
| WO2021252449A1 (en) * | 2020-06-08 | 2021-12-16 | Harm Reduction Therapeutics, Inc. | Sterilized formulations |
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| JPH0647533B2 (ja) * | 1984-08-10 | 1994-06-22 | 裕 水島 | ４−ビフエニリル酢酸系化合物含有脂肪乳剤 |
| US4816247A (en) * | 1985-09-11 | 1989-03-28 | American Cyanamid Company | Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs |
| ATE183092T1 (de) * | 1995-10-28 | 1999-08-15 | Braun Melsungen Ag | Lokalanästhetika und/oder zentralanalgetika enthaltende pharmazeutische zusammensetzungen |
| GB9721746D0 (en) | 1997-10-15 | 1997-12-10 | Panos Therapeutics Limited | Compositions |
| US6541021B1 (en) * | 1999-03-18 | 2003-04-01 | Durect Corporation | Devices and methods for pain management |
| US6835194B2 (en) * | 1999-03-18 | 2004-12-28 | Durect Corporation | Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners |
| US6455525B1 (en) * | 1999-11-04 | 2002-09-24 | Cephalon, Inc. | Heterocyclic substituted pyrazolones |
| CN1525856A (zh) * | 2001-05-11 | 2004-09-01 | 三菱制药株式会社 | 含吡唑啉酮衍生物的稳定的高浓度注射剂 |
| ATE522498T1 (de) * | 2002-01-25 | 2011-09-15 | Theravance Inc | Sedative hypnotisch wirkende verbindungen mit kurzer wirkungsdauer zur anaesthesie und sedierung |
| JP2004043479A (ja) * | 2002-07-11 | 2004-02-12 | Taiho Yakuhin Kogyo Kk | 経鼻吸収用組成物 |
| UA80447C2 (en) * | 2002-10-08 | 2007-09-25 | Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic | |
| ZA200502612B (en) * | 2002-10-08 | 2007-07-25 | Rinat Neuroscience Corp | Methods for treating post-surgical pain by administering a nerve crowth factor antagonist and compositions containing the same |
| US7648982B2 (en) * | 2003-02-28 | 2010-01-19 | Ym Biosciences Inc. | Opioid delivery system |
| JP2004275852A (ja) * | 2003-03-14 | 2004-10-07 | Mitsubishi Heavy Ind Ltd | 排煙脱硝触媒及びその製造方法 |
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-
2009
- 2009-04-15 US US12/424,382 patent/US20090286832A1/en not_active Abandoned
- 2009-04-28 KR KR1020107015502A patent/KR101361479B1/ko not_active Expired - Fee Related
- 2009-04-28 BR BRPI0907224-1A patent/BRPI0907224A2/pt not_active IP Right Cessation
- 2009-04-28 CN CN2009801021888A patent/CN101938963A/zh active Pending
- 2009-04-28 EA EA201000991A patent/EA201000991A1/ru unknown
- 2009-04-28 JP JP2011509539A patent/JP5689053B2/ja not_active Expired - Fee Related
- 2009-04-28 EP EP09747145A patent/EP2276440A4/en not_active Withdrawn
- 2009-04-28 CA CA2710546A patent/CA2710546A1/en not_active Abandoned
- 2009-04-28 AU AU2009246713A patent/AU2009246713B2/en not_active Ceased
- 2009-04-28 MX MX2010007698A patent/MX2010007698A/es not_active Application Discontinuation
- 2009-04-28 WO PCT/US2009/041991 patent/WO2009140059A2/en not_active Ceased
- 2009-04-28 NZ NZ586461A patent/NZ586461A/en not_active IP Right Cessation
- 2009-05-13 AR ARP090101725A patent/AR071779A1/es not_active Application Discontinuation
- 2009-05-14 TW TW098115948A patent/TWI413531B/zh not_active IP Right Cessation
- 2009-05-14 TW TW102123473A patent/TW201406403A/zh unknown
-
2010
- 2010-06-22 ZA ZA2010/04392A patent/ZA201004392B/en unknown
- 2010-11-04 IL IL209145A patent/IL209145A0/en unknown
-
2014
- 2014-05-23 JP JP2014107385A patent/JP5889364B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW201406403A (zh) | 2014-02-16 |
| TW201006508A (en) | 2010-02-16 |
| AU2009246713A1 (en) | 2009-11-19 |
| KR101361479B1 (ko) | 2014-02-12 |
| JP5889364B2 (ja) | 2016-03-22 |
| ZA201004392B (en) | 2011-06-29 |
| JP5689053B2 (ja) | 2015-03-25 |
| NZ586461A (en) | 2012-07-27 |
| CN101938963A (zh) | 2011-01-05 |
| AU2009246713B2 (en) | 2012-10-25 |
| EA201000991A1 (ru) | 2011-06-30 |
| JP2014205681A (ja) | 2014-10-30 |
| WO2009140059A3 (en) | 2010-01-07 |
| JP2011520883A (ja) | 2011-07-21 |
| EP2276440A2 (en) | 2011-01-26 |
| US20090286832A1 (en) | 2009-11-19 |
| KR20100126270A (ko) | 2010-12-01 |
| WO2009140059A2 (en) | 2009-11-19 |
| EP2276440A4 (en) | 2011-06-29 |
| AR071779A1 (es) | 2010-07-14 |
| BRPI0907224A2 (pt) | 2019-02-26 |
| MX2010007698A (es) | 2010-11-22 |
| TWI413531B (zh) | 2013-11-01 |
| IL209145A0 (en) | 2011-01-31 |
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| EEER | Examination request | ||
| FZDE | Discontinued |
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