CA2710166A1 - Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein - Google Patents
Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein Download PDFInfo
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- CA2710166A1 CA2710166A1 CA2710166A CA2710166A CA2710166A1 CA 2710166 A1 CA2710166 A1 CA 2710166A1 CA 2710166 A CA2710166 A CA 2710166A CA 2710166 A CA2710166 A CA 2710166A CA 2710166 A1 CA2710166 A1 CA 2710166A1
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- 238000007910 systemic administration Methods 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000003146 transient transfection Methods 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
- 230000005951 type IV hypersensitivity Effects 0.000 description 1
- 208000027930 type IV hypersensitivity disease Diseases 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000007501 viral attachment Effects 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000017613 viral reproduction Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 238000002424 x-ray crystallography Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20251—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20251—Methods of production or purification of viral material
- C12N2760/20252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1535307P | 2007-12-20 | 2007-12-20 | |
| US61/015,353 | 2007-12-20 | ||
| PCT/US2008/013817 WO2009085172A1 (en) | 2007-12-20 | 2008-12-18 | Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2710166A1 true CA2710166A1 (en) | 2009-07-09 |
Family
ID=40418917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2710166A Abandoned CA2710166A1 (en) | 2007-12-20 | 2008-12-18 | Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090162321A1 (https=) |
| EP (1) | EP2225264A1 (https=) |
| JP (1) | JP2011507514A (https=) |
| AR (1) | AR069885A1 (https=) |
| AU (1) | AU2008343919B2 (https=) |
| CA (1) | CA2710166A1 (https=) |
| CL (1) | CL2008003821A1 (https=) |
| WO (1) | WO2009085172A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5675789B2 (ja) * | 2009-06-08 | 2015-02-25 | ザ ユニバーシティー オブ ウェスタン オンタリオＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｗｅｓｔｅｒｎ Ｏｎｔａｒｉｏ | 免疫接種のための発現ベクターとしての水疱性口内炎ウイルスの異なる複数の抗原型 |
| US9610346B2 (en) * | 2012-03-23 | 2017-04-04 | International Aids Vaccine Initiative | Recombinant viral vectors |
| CN111344008A (zh) * | 2017-09-15 | 2020-06-26 | 俄亥俄州创新基金会 | 用于预防呼吸道合胞病毒(rsv)感染的疫苗及其制备和使用方法 |
| WO2019070704A1 (en) * | 2017-10-02 | 2019-04-11 | Georgia Tech Research Corporation | METHODS AND COMPOSITIONS FOR ENGINEERING SYNTHESIS BIOLOGICAL SWITCHES FOR REMOTE CONTROL OF BIOLOGICAL ACTIVITY |
| CN109750006A (zh) * | 2019-01-14 | 2019-05-14 | 青岛农业大学 | 一种犬瘟热病毒复制缺陷毒株及其构建方法 |
| CN112430582B (zh) * | 2020-12-04 | 2022-05-03 | 北京艺妙神州医药科技有限公司 | 一种慢病毒稳定包装细胞系及其制备方法 |
| CN115725657B (zh) * | 2022-09-16 | 2024-06-04 | 中国科学院广州生物医药与健康研究院 | 一种节段化的水泡性口炎病毒载体及其制备方法和应用 |
| CN117051040B (zh) * | 2023-08-15 | 2024-10-01 | 北京百普赛斯生物科技股份有限公司 | Vsv△g复制缺陷型病毒制备及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US6596529B1 (en) * | 1997-05-02 | 2003-07-22 | Uab Research Foundation | Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof |
| JP4198195B2 (ja) * | 1997-05-02 | 2008-12-17 | ザ ユーエイビー リサーチ ファンデイション | 負鎖ｒｎａウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 |
| EP1478750B1 (en) * | 1999-11-23 | 2012-08-08 | Mayo Foundation For Medical Education And Research | Gene expression by positive feedback activation of a cell type-specific promoter |
| EP1633860A2 (en) * | 2003-06-09 | 2006-03-15 | Wyeth | IMPROVED METHOD FOR THE RECOVERY OF NON-SEGMENTED, NEGATIVE-STRANDED RNA VIRUSES FROM cDNA |
| US8008268B2 (en) * | 2006-07-25 | 2011-08-30 | Merial Limited | Vaccines against vesicular stomatitis |
-
2008
- 2008-12-16 US US12/335,778 patent/US20090162321A1/en not_active Abandoned
- 2008-12-18 WO PCT/US2008/013817 patent/WO2009085172A1/en not_active Ceased
- 2008-12-18 JP JP2010539474A patent/JP2011507514A/ja active Pending
- 2008-12-18 CA CA2710166A patent/CA2710166A1/en not_active Abandoned
- 2008-12-18 AU AU2008343919A patent/AU2008343919B2/en not_active Ceased
- 2008-12-18 EP EP08867848A patent/EP2225264A1/en not_active Withdrawn
- 2008-12-19 CL CL2008003821A patent/CL2008003821A1/es unknown
- 2008-12-19 AR ARP080105638A patent/AR069885A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2008003821A1 (es) | 2009-04-03 |
| JP2011507514A (ja) | 2011-03-10 |
| AU2008343919B2 (en) | 2013-01-17 |
| AR069885A1 (es) | 2010-02-24 |
| AU2008343919A1 (en) | 2009-07-09 |
| WO2009085172A1 (en) | 2009-07-09 |
| EP2225264A1 (en) | 2010-09-08 |
| US20090162321A1 (en) | 2009-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20141006 |