CA2709208A1 - Phenylephrine pharmaceutical formulations and compositions for transmucosal absorption - Google Patents
Phenylephrine pharmaceutical formulations and compositions for transmucosal absorption Download PDFInfo
- Publication number
- CA2709208A1 CA2709208A1 CA2709208A CA2709208A CA2709208A1 CA 2709208 A1 CA2709208 A1 CA 2709208A1 CA 2709208 A CA2709208 A CA 2709208A CA 2709208 A CA2709208 A CA 2709208A CA 2709208 A1 CA2709208 A1 CA 2709208A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- phenylephrine
- release
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229960001802 phenylephrine Drugs 0.000 title claims abstract description 264
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 title claims abstract description 253
- 238000010521 absorption reaction Methods 0.000 title claims abstract description 30
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 28
- 239000000203 mixture Substances 0.000 claims abstract description 164
- 150000003839 salts Chemical class 0.000 claims abstract description 36
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- 230000009885 systemic effect Effects 0.000 claims abstract description 25
- 238000000034 method Methods 0.000 claims abstract description 21
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Classifications
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
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- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1222307P | 2007-12-07 | 2007-12-07 | |
| US61/012,223 | 2007-12-07 | ||
| PCT/US2008/085523 WO2009076165A1 (en) | 2007-12-07 | 2008-12-04 | Phenylephrine pharmaceutical formulations and compositions for transmucosal absorption |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2709208A1 true CA2709208A1 (en) | 2009-06-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2709208A Abandoned CA2709208A1 (en) | 2007-12-07 | 2008-12-04 | Phenylephrine pharmaceutical formulations and compositions for transmucosal absorption |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090280160A1 (https=) |
| EP (1) | EP2237767A1 (https=) |
| JP (1) | JP2011506337A (https=) |
| KR (1) | KR20100102632A (https=) |
| CN (1) | CN101938991A (https=) |
| AR (1) | AR069572A1 (https=) |
| AU (1) | AU2008335464A1 (https=) |
| BR (1) | BRPI0820673A2 (https=) |
| CA (1) | CA2709208A1 (https=) |
| CL (1) | CL2008003615A1 (https=) |
| CO (1) | CO6321221A2 (https=) |
| MX (1) | MX2010006284A (https=) |
| PE (1) | PE20091084A1 (https=) |
| RU (1) | RU2010127737A (https=) |
| TW (1) | TW200932208A (https=) |
| WO (1) | WO2009076165A1 (https=) |
| ZA (1) | ZA201004654B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12286451B2 (en) | 2020-11-23 | 2025-04-29 | Medtech Products Inc. | Borate ester complexes of α-hydroxy carboxylic acids and their conjugate base buffers |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2899492C (en) * | 2013-02-13 | 2019-09-17 | The Procter & Gamble Company | Anise flavored medication |
| US20190008759A1 (en) * | 2014-07-03 | 2019-01-10 | Darren Rubin | Safer and more effective methods of transmucosal delivery for raising blood pressure and stimulating the body |
| MA41689A (fr) * | 2014-10-15 | 2017-08-22 | Bioxcel Corp | Prévention ou traitement de troubles du sommeil au moyen d'une formulation de dexmédétomidine |
| US12427121B2 (en) | 2016-05-05 | 2025-09-30 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine compositions |
| US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
| US12433850B2 (en) | 2016-05-05 | 2025-10-07 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine and prodrug compositions |
| KR20230137362A (ko) * | 2016-05-05 | 2023-10-04 | 어퀘스티브 테라퓨틱스, 아이엔씨. | 강화된 전달 에프네프린 조성물 |
| KR102793584B1 (ko) | 2016-12-31 | 2025-04-09 | 바이오엑셀 테라퓨틱스 인코포레이티드 | 불안의 치료를 위한 설하 덱스메데토미딘의 용도 |
| RU2751193C2 (ru) | 2017-01-11 | 2021-07-12 | Ферринг Б.В. | Быстро распадающаяся фармацевтическая композиция |
| WO2019021476A1 (ja) * | 2017-07-28 | 2019-01-31 | 社会医療法人蘇西厚生会 まつなみリサーチパーク | アレルギー症状の予防又は治療剤 |
| IL313551A (en) * | 2017-09-27 | 2024-08-01 | Aquestive Therapeutics Inc | Enhanced delivery epinephrine and prodrug compositions |
| PL3813802T3 (pl) | 2018-06-27 | 2025-04-22 | Bioxcel Therapeutics, Inc. | Formulacje błony zawierające deksmedetomidynę i sposoby ich wytwarzania |
| EP3999058A4 (en) | 2019-07-19 | 2023-05-03 | Bioxcel Therapeutics, Inc. | NON-SEDATIVE DEXMEDETOMIDINE-BASED TREATMENT REGIMEN |
| EP4157451B1 (en) * | 2020-06-02 | 2024-12-04 | Mohamed Hussein Hamdan | Sublingual formulation for hypotension and syncope |
| EP4422607A4 (en) | 2021-10-25 | 2025-09-03 | Aquestive Therapeutics Inc | ORAL AND NASAL COMPOSITIONS AND METHODS OF TREATMENT |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
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-
2008
- 2008-12-03 PE PE2008002013A patent/PE20091084A1/es not_active Application Discontinuation
- 2008-12-04 CL CL2008003615A patent/CL2008003615A1/es unknown
- 2008-12-04 TW TW097147189A patent/TW200932208A/zh unknown
- 2008-12-04 EP EP08858399A patent/EP2237767A1/en not_active Withdrawn
- 2008-12-04 AU AU2008335464A patent/AU2008335464A1/en not_active Abandoned
- 2008-12-04 JP JP2010537049A patent/JP2011506337A/ja not_active Withdrawn
- 2008-12-04 MX MX2010006284A patent/MX2010006284A/es not_active Application Discontinuation
- 2008-12-04 BR BRPI0820673-2A patent/BRPI0820673A2/pt not_active IP Right Cessation
- 2008-12-04 US US12/328,429 patent/US20090280160A1/en not_active Abandoned
- 2008-12-04 CA CA2709208A patent/CA2709208A1/en not_active Abandoned
- 2008-12-04 WO PCT/US2008/085523 patent/WO2009076165A1/en not_active Ceased
- 2008-12-04 RU RU2010127737/15A patent/RU2010127737A/ru not_active Application Discontinuation
- 2008-12-04 AR ARP080105286A patent/AR069572A1/es not_active Application Discontinuation
- 2008-12-04 KR KR1020107014733A patent/KR20100102632A/ko not_active Withdrawn
- 2008-12-04 CN CN2008801263844A patent/CN101938991A/zh active Pending
-
2010
- 2010-07-01 ZA ZA2010/04654A patent/ZA201004654B/en unknown
- 2010-07-07 CO CO10082162A patent/CO6321221A2/es not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12286451B2 (en) | 2020-11-23 | 2025-04-29 | Medtech Products Inc. | Borate ester complexes of α-hydroxy carboxylic acids and their conjugate base buffers |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201004654B (en) | 2011-03-30 |
| WO2009076165A1 (en) | 2009-06-18 |
| AU2008335464A1 (en) | 2009-06-18 |
| JP2011506337A (ja) | 2011-03-03 |
| EP2237767A1 (en) | 2010-10-13 |
| CL2008003615A1 (es) | 2009-10-16 |
| BRPI0820673A2 (pt) | 2015-06-16 |
| RU2010127737A (ru) | 2012-01-20 |
| PE20091084A1 (es) | 2009-07-23 |
| KR20100102632A (ko) | 2010-09-24 |
| US20090280160A1 (en) | 2009-11-12 |
| AR069572A1 (es) | 2010-02-03 |
| MX2010006284A (es) | 2010-09-07 |
| CO6321221A2 (es) | 2011-09-20 |
| CN101938991A (zh) | 2011-01-05 |
| TW200932208A (en) | 2009-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20131204 |