AR069572A1 - Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal - Google Patents
Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosalInfo
- Publication number
- AR069572A1 AR069572A1 ARP080105286A ARP080105286A AR069572A1 AR 069572 A1 AR069572 A1 AR 069572A1 AR P080105286 A ARP080105286 A AR P080105286A AR P080105286 A ARP080105286 A AR P080105286A AR 069572 A1 AR069572 A1 AR 069572A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- phenylephrine
- phenylefrine
- pharmaceutical formulations
- transmucosal absorption
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composiciones farmacéuticas que comprenden fenilefrina o su sal aceptable para uso farmacéutico, un dispositivo portador y de administracion, y métodos para administrar las composiciones farmacéuticas donde la composicion se formula para absorcion sistémica de fenilefrina que evita el metabolismo de primer paso. Las composiciones se formulan para ser aplicadas a la mucosa oral de un animal para permitir la administracion sistémica mejorada de la forma activa para uso terapéutico de fenilefrina, para alivio temporario de congestion y/o resfriados.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1222307P | 2007-12-07 | 2007-12-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR069572A1 true AR069572A1 (es) | 2010-02-03 |
Family
ID=40510498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080105286A AR069572A1 (es) | 2007-12-07 | 2008-12-04 | Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal |
Country Status (17)
Country | Link |
---|---|
US (1) | US20090280160A1 (es) |
EP (1) | EP2237767A1 (es) |
JP (1) | JP2011506337A (es) |
KR (1) | KR20100102632A (es) |
CN (1) | CN101938991A (es) |
AR (1) | AR069572A1 (es) |
AU (1) | AU2008335464A1 (es) |
BR (1) | BRPI0820673A2 (es) |
CA (1) | CA2709208A1 (es) |
CL (1) | CL2008003615A1 (es) |
CO (1) | CO6321221A2 (es) |
MX (1) | MX2010006284A (es) |
PE (1) | PE20091084A1 (es) |
RU (1) | RU2010127737A (es) |
TW (1) | TW200932208A (es) |
WO (1) | WO2009076165A1 (es) |
ZA (1) | ZA201004654B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014127118A1 (en) | 2013-02-13 | 2014-08-21 | The Procter & Gamble Company | Anise flavored medication |
US20190008759A1 (en) * | 2014-07-03 | 2019-01-10 | Darren Rubin | Safer and more effective methods of transmucosal delivery for raising blood pressure and stimulating the body |
MA41689A (fr) * | 2014-10-15 | 2017-08-22 | Bioxcel Corp | Prévention ou traitement de troubles du sommeil au moyen d'une formulation de dexmédétomidine |
KR20230137362A (ko) * | 2016-05-05 | 2023-10-04 | 어퀘스티브 테라퓨틱스, 아이엔씨. | 강화된 전달 에프네프린 조성물 |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
KR20240031326A (ko) | 2016-12-31 | 2024-03-07 | 바이오엑셀 테라퓨틱스 인코포레이티드 | 불안의 치료를 위한 설하 덱스메데토미딘의 용도 |
RU2751193C2 (ru) | 2017-01-11 | 2021-07-12 | Ферринг Б.В. | Быстро распадающаяся фармацевтическая композиция |
WO2019021476A1 (ja) * | 2017-07-28 | 2019-01-31 | 社会医療法人蘇西厚生会 まつなみリサーチパーク | アレルギー症状の予防又は治療剤 |
JP2020535162A (ja) * | 2017-09-27 | 2020-12-03 | アクエスティブ セラピューティクス インコーポレイテッド | 増強された送達のエピネフリン及びプロドラッグ組成物 |
MX2020014000A (es) | 2018-06-27 | 2021-06-15 | Bioxcel Therapeutics Inc | Formulaciones en lámina que contienen dexmedetomidina y métodos para producirlas. |
MX2022000709A (es) | 2019-07-19 | 2022-05-19 | Bioxcel Therapeutics Inc | Regimenes de tratamiento con dexmedetomidina no sedante. |
US20210369721A1 (en) * | 2020-06-02 | 2021-12-02 | Mohamed Hussein Hamdan | Sublingual formulation for hypotension and syncope |
US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (51)
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US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
US4427681A (en) * | 1982-09-16 | 1984-01-24 | Richardson-Vicks, Inc. | Thixotropic compositions easily convertible to pourable liquids |
US5025019A (en) * | 1984-04-09 | 1991-06-18 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
US4623664A (en) * | 1985-10-31 | 1986-11-18 | University Of Iowa Research Foundation | Oil suspended phenylephrine |
US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US5085865A (en) * | 1989-04-12 | 1992-02-04 | Warner-Lambert Company | Sustained release pharmaceutical preparations containing an analgesic and a decongestant |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
EP0542926B1 (en) * | 1990-08-07 | 1995-02-15 | Pfizer Inc. | Use of interfacially-polymerized membranes in delivery devices |
US5518730A (en) * | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
US5458879A (en) * | 1994-03-03 | 1995-10-17 | The Procter & Gamble Company | Oral vehicle compositions |
GB9422571D0 (en) * | 1994-11-09 | 1995-01-04 | Whitehall Lab Ltd | Haemorrihoidal compositions and method of use |
US5827531A (en) * | 1994-12-02 | 1998-10-27 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Microcapsules and methods for making |
NL1005394C1 (nl) * | 1996-04-01 | 1997-10-02 | Kokbing Lo | Bevestigingselement en band bevestigd met bevestigingselement. |
ATE320796T1 (de) * | 1996-12-23 | 2006-04-15 | Sla Pharma Ag | Pharmazeutische zubereitung zur behandlung der analinkontinenz und analem juckreiz |
DE69833000T2 (de) * | 1997-09-26 | 2006-09-07 | Noven Pharmaceuticals, Inc., Miami | Bio-klebemittelzusammensetzungen |
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US7815937B2 (en) * | 1998-10-27 | 2010-10-19 | Biovail Laboratories International Srl | Quick dissolve compositions and tablets based thereon |
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US6267986B1 (en) * | 1999-09-24 | 2001-07-31 | Ranbaxy Laboratories Limited | Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine |
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US6955821B2 (en) * | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
AU2001261744A1 (en) * | 2000-05-19 | 2001-12-03 | Npd Llc | Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements |
US20020022057A1 (en) * | 2000-08-17 | 2002-02-21 | Battey Alyce S. | Oral delivery of pharmaceuticals via encapsulation |
US20030236275A1 (en) * | 2002-06-20 | 2003-12-25 | Schering Corporation | Treatment methods of nasal congestion and nasal obstruction |
US6585997B2 (en) * | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
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US20030114535A1 (en) * | 2001-12-14 | 2003-06-19 | Jame Fine Chemicals, Inc. | Dextrochlorpheniramine tannate |
US20040122107A1 (en) * | 2002-09-13 | 2004-06-24 | Fine Jeffrey R | Method of alleviating barometric-induced symptoms in airline passengers |
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US6979689B2 (en) * | 2002-12-20 | 2005-12-27 | Pediamed Pharmaceuticals, Inc. | Compositions and methods for treating upper respiratory congestion |
US20040214215A1 (en) * | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
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US20070219253A1 (en) * | 2003-09-17 | 2007-09-20 | Gul Balwani | Decongestant / antihistaminic / expectorant compositions |
US20050095288A1 (en) * | 2003-11-03 | 2005-05-05 | Andrx Labs, Llc | Decongestant and expectorant tablets |
US20050266032A1 (en) * | 2003-12-17 | 2005-12-01 | Sovereign Pharmaceuticals, Ltd. | Dosage form containing multiple drugs |
JP2007517806A (ja) * | 2004-01-15 | 2007-07-05 | オーラル バイオサイエンス ピーティーワイ. リミテッド | 口腔用麻酔ゲル |
NZ555909A (en) * | 2004-12-13 | 2009-11-27 | Mcneil Ppc Inc | Compositions and methods for reducing the degradation of phenylephrine by oxygen |
US8318210B2 (en) * | 2005-02-28 | 2012-11-27 | Neos Therapeutics, Lp | Compositions and methods of making sustained release liquid formulations |
NZ588134A (en) * | 2005-06-17 | 2010-11-26 | Aft Pharmaceuticals Ltd | Novel pharmaceutical for use in a method for treatment of upper respiratory mucosal congestion |
US20070141147A1 (en) * | 2005-12-21 | 2007-06-21 | Auriga Laboratories, Inc. | Sequential release pharmaceutical formulations |
US8940796B2 (en) * | 2006-02-21 | 2015-01-27 | Wyeth Llc | Phenylephrine liquid formulations |
US20080014274A1 (en) * | 2006-07-14 | 2008-01-17 | Wyeth | Enhanced stability phenylephrine liquid compositions |
US9005652B2 (en) * | 2006-07-25 | 2015-04-14 | Wyeth | Chewable tablet containing phenylephrine |
US7378082B1 (en) * | 2007-11-05 | 2008-05-27 | Inspire Pharmaceuticals, Inc. | Method for treating allergic rhinitis without adverse effects |
-
2008
- 2008-12-03 PE PE2008002013A patent/PE20091084A1/es not_active Application Discontinuation
- 2008-12-04 WO PCT/US2008/085523 patent/WO2009076165A1/en active Application Filing
- 2008-12-04 AR ARP080105286A patent/AR069572A1/es not_active Application Discontinuation
- 2008-12-04 MX MX2010006284A patent/MX2010006284A/es not_active Application Discontinuation
- 2008-12-04 TW TW097147189A patent/TW200932208A/zh unknown
- 2008-12-04 CA CA2709208A patent/CA2709208A1/en not_active Abandoned
- 2008-12-04 EP EP08858399A patent/EP2237767A1/en not_active Withdrawn
- 2008-12-04 CL CL2008003615A patent/CL2008003615A1/es unknown
- 2008-12-04 AU AU2008335464A patent/AU2008335464A1/en not_active Abandoned
- 2008-12-04 KR KR1020107014733A patent/KR20100102632A/ko not_active Application Discontinuation
- 2008-12-04 BR BRPI0820673-2A patent/BRPI0820673A2/pt not_active IP Right Cessation
- 2008-12-04 US US12/328,429 patent/US20090280160A1/en not_active Abandoned
- 2008-12-04 CN CN2008801263844A patent/CN101938991A/zh active Pending
- 2008-12-04 JP JP2010537049A patent/JP2011506337A/ja not_active Withdrawn
- 2008-12-04 RU RU2010127737/15A patent/RU2010127737A/ru not_active Application Discontinuation
-
2010
- 2010-07-01 ZA ZA2010/04654A patent/ZA201004654B/en unknown
- 2010-07-07 CO CO10082162A patent/CO6321221A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101938991A (zh) | 2011-01-05 |
JP2011506337A (ja) | 2011-03-03 |
CA2709208A1 (en) | 2009-06-18 |
CO6321221A2 (es) | 2011-09-20 |
WO2009076165A1 (en) | 2009-06-18 |
US20090280160A1 (en) | 2009-11-12 |
RU2010127737A (ru) | 2012-01-20 |
PE20091084A1 (es) | 2009-07-23 |
BRPI0820673A2 (pt) | 2015-06-16 |
CL2008003615A1 (es) | 2009-10-16 |
AU2008335464A1 (en) | 2009-06-18 |
KR20100102632A (ko) | 2010-09-24 |
ZA201004654B (en) | 2011-03-30 |
EP2237767A1 (en) | 2010-10-13 |
TW200932208A (en) | 2009-08-01 |
MX2010006284A (es) | 2010-09-07 |
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