CA2696829C - Oxadiazole diaryl compounds - Google Patents

Oxadiazole diaryl compounds Download PDF

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Publication number
CA2696829C
CA2696829C CA2696829A CA2696829A CA2696829C CA 2696829 C CA2696829 C CA 2696829C CA 2696829 A CA2696829 A CA 2696829A CA 2696829 A CA2696829 A CA 2696829A CA 2696829 C CA2696829 C CA 2696829C
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Canada
Prior art keywords
mmol
formula
title compound
ethyl acetate
purity
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Expired - Fee Related
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CA2696829A
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English (en)
French (fr)
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CA2696829A1 (en
Inventor
Cyril Montagne
Anna Quattropani
Wolfgang Sauer
Agnes Bombrun
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Merck Serono SA
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Merck Serono SA
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Publication of CA2696829A1 publication Critical patent/CA2696829A1/en
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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CA2696829A 2007-10-04 2008-10-01 Oxadiazole diaryl compounds Expired - Fee Related CA2696829C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07117925 2007-10-04
EP07117925.3 2007-10-04
US99813607P 2007-10-09 2007-10-09
US60/998,136 2007-10-09
PCT/EP2008/063185 WO2009043890A1 (en) 2007-10-04 2008-10-01 Oxadiazole diaryl compounds

Publications (2)

Publication Number Publication Date
CA2696829A1 CA2696829A1 (en) 2009-04-09
CA2696829C true CA2696829C (en) 2017-07-04

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CA2696829A Expired - Fee Related CA2696829C (en) 2007-10-04 2008-10-01 Oxadiazole diaryl compounds

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US (2) US8404676B2 (OSRAM)
EP (1) EP2193126B1 (OSRAM)
JP (3) JP5727223B2 (OSRAM)
KR (1) KR20100083814A (OSRAM)
CN (2) CN101815707B (OSRAM)
AR (1) AR068730A1 (OSRAM)
AU (1) AU2008306886B2 (OSRAM)
BR (1) BRPI0817597A2 (OSRAM)
CA (1) CA2696829C (OSRAM)
EA (1) EA201070423A1 (OSRAM)
ES (1) ES2547877T3 (OSRAM)
IL (1) IL204520A (OSRAM)
MX (1) MX2010003614A (OSRAM)
WO (1) WO2009043890A1 (OSRAM)
ZA (1) ZA201001217B (OSRAM)

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