CA2690488C - Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof - Google Patents
Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof Download PDFInfo
- Publication number
- CA2690488C CA2690488C CA2690488A CA2690488A CA2690488C CA 2690488 C CA2690488 C CA 2690488C CA 2690488 A CA2690488 A CA 2690488A CA 2690488 A CA2690488 A CA 2690488A CA 2690488 C CA2690488 C CA 2690488C
- Authority
- CA
- Canada
- Prior art keywords
- ranges
- naproxen
- weight
- amount
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2690488A CA2690488C (en) | 2010-01-19 | 2010-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| SI201131992T SI2525789T1 (sl) | 2010-01-19 | 2011-01-19 | Farmacevtske formulacije naproksena za enkapsulacijo v mehko želatino in njihove kombinacije |
| ES11734283T ES2880813T3 (es) | 2010-01-19 | 2011-01-19 | Formulaciones farmacéuticas de naproxeno para encapsulación en gel blando y combinaciones de las mismas |
| JP2012549215A JP5975884B2 (ja) | 2010-01-19 | 2011-01-19 | ソフトゲルカプセル化のためのナプロキセンの医薬処方およびその組合せ |
| EP21177143.1A EP3909567B1 (en) | 2010-01-19 | 2011-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| HUE11734283A HUE055771T2 (hu) | 2010-01-19 | 2011-01-19 | Naproxén gyógyászati kiszerelései lágy gél kapszulázáshoz, és ezek kombinációi |
| MX2012008300A MX358636B (es) | 2010-01-19 | 2011-01-19 | Formulaciones farmacéuticas de naproxeno para la encapsulación en gel blando y combinaciones de las mismas. |
| PT117342832T PT2525789T (pt) | 2010-01-19 | 2011-01-19 | Formulações farmacêuticas de naproxeno para encapsulação de gel mole e combinações das mesmas |
| PL11734283T PL2525789T3 (pl) | 2010-01-19 | 2011-01-19 | Farmaceutyczne formulacje naproksenu do kapsułkowania w miękkich kapsułkach żelowych i ich kombinacje |
| EP11734283.2A EP2525789B1 (en) | 2010-01-19 | 2011-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| DK11734283.2T DK2525789T3 (da) | 2010-01-19 | 2011-01-19 | Farmaceutiske formuleringer af naproxen til softgel-indkapsling og kombinationer deraf |
| PCT/CA2011/000059 WO2011088553A1 (en) | 2010-01-19 | 2011-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| AU2011207061A AU2011207061B2 (en) | 2010-01-19 | 2011-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| US13/574,159 US9480667B2 (en) | 2010-01-19 | 2011-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| JP2016007253A JP2016094462A (ja) | 2010-01-19 | 2016-01-18 | ソフトゲルカプセル化のためのナプロキセンの医薬処方およびその組合せ |
| US15/285,968 US10463637B2 (en) | 2010-01-19 | 2016-10-05 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| US16/583,903 US11896566B2 (en) | 2010-01-19 | 2019-09-26 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| US18/400,069 US12605348B2 (en) | 2010-01-19 | 2023-12-29 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2690488A CA2690488C (en) | 2010-01-19 | 2010-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2690488A1 CA2690488A1 (en) | 2011-07-19 |
| CA2690488C true CA2690488C (en) | 2013-06-11 |
Family
ID=44303618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2690488A Active CA2690488C (en) | 2010-01-19 | 2010-01-19 | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9480667B2 (https=) |
| EP (2) | EP2525789B1 (https=) |
| JP (2) | JP5975884B2 (https=) |
| AU (1) | AU2011207061B2 (https=) |
| CA (1) | CA2690488C (https=) |
| DK (1) | DK2525789T3 (https=) |
| ES (1) | ES2880813T3 (https=) |
| HU (1) | HUE055771T2 (https=) |
| MX (1) | MX358636B (https=) |
| PL (1) | PL2525789T3 (https=) |
| PT (1) | PT2525789T (https=) |
| SI (1) | SI2525789T1 (https=) |
| WO (1) | WO2011088553A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201301626D0 (en) | 2013-01-30 | 2013-03-13 | Dignity Sciences Ltd | Composition comprising 15-OHEPA and methods of using the same |
| ES2784240T3 (es) * | 2014-06-04 | 2020-09-23 | Ds Biopharma Ltd | Composiciones farmacéuticas que comprenden DGLA y uso de las mismas |
| CN104083339A (zh) * | 2014-08-04 | 2014-10-08 | 人福普克药业（武汉）有限公司 | 萘普生钠软胶囊及其制备方法 |
| US10368284B2 (en) * | 2014-11-12 | 2019-07-30 | T-Mobile Usa, Inc. | Quality of experience-based handover management |
| CN117402059A (zh) | 2015-05-13 | 2024-01-16 | Ds生物制药有限公司 | 包含15-氧代-epa或15-氧代-dgla的组合物及其制备和使用方法 |
| JP2018520197A (ja) | 2015-07-21 | 2018-07-26 | アフィミューン リミテッド | 癌及び神経疾患の治療または予防において使用するための、１５−ｈｅｐｅを含む組成物 |
| KR20180094516A (ko) | 2015-12-18 | 2018-08-23 | 애피뮨 리미티드 | 15-hepe를 포함하는 조성물 및 이를 사용하는 방법 |
| US11911517B2 (en) | 2018-05-16 | 2024-02-27 | Bayer Healthcare Llc | High concentration suspension formulation for cold and flu soft gel capsule medications |
| CN109692127A (zh) * | 2019-03-15 | 2019-04-30 | 王征 | 一种密封小胶囊的制备方法 |
| AU2020263295B2 (en) * | 2019-04-26 | 2025-01-23 | R.P. Scherer Technologies, Llc | Mini softgel naproxen composition |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
| US20220233452A1 (en) * | 2021-01-25 | 2022-07-28 | R.P. Scherer Technologies, Llc | Mini softgel naproxen composition |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA821577B (en) | 1981-04-06 | 1983-03-30 | Boots Co Plc | Therapeutic agents |
| US4443428A (en) * | 1982-06-21 | 1984-04-17 | Euroceltique, S.A. | Extended action controlled release compositions |
| US5071643A (en) | 1986-10-17 | 1991-12-10 | R. P. Scherer Corporation | Solvent system enhancing the solubility of pharmaceuticals for encapsulation |
| US5073371A (en) | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| WO1995007103A1 (en) * | 1993-09-07 | 1995-03-16 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| EP0741560A1 (en) * | 1994-01-24 | 1996-11-13 | The Procter & Gamble Company | Process for solubilizing difficultly soluble pharmaceutical actives |
| US5484606A (en) * | 1994-01-24 | 1996-01-16 | The Procter & Gamble Company | Process for reducing the precipitation of difficulty soluble pharmaceutical actives |
| US5641512A (en) | 1995-03-29 | 1997-06-24 | The Procter & Gamble Company | Soft gelatin capsule compositions |
| EP1049459B1 (en) * | 1998-01-20 | 2009-04-22 | Applied Analytical Industries, Inc. | Oral liquid compositions |
| US6383515B2 (en) * | 1999-05-28 | 2002-05-07 | Sawyer Maryjean | Solvent system for enhancing solubility |
| US6387400B1 (en) | 2000-08-29 | 2002-05-14 | R.P. Scherer Technologies, Inc. | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
| US20090318558A1 (en) * | 2003-02-12 | 2009-12-24 | Jae-Hwan Kim | Solvent system of hardly soluble drug with improved dissolution rate |
| EP1605916A4 (en) * | 2003-02-12 | 2012-02-22 | R & P Korea Co Ltd | SOLVENT SYSTEM OF A SMOOTH MEDICAMENT WITH IMPROVED ELUTION RATE |
| US20070053868A1 (en) * | 2005-03-08 | 2007-03-08 | Banner Pharmacaps, Inc. | Solvent system for enhancing the solubility of pharmaceutical agents |
| US7582679B2 (en) * | 2006-02-03 | 2009-09-01 | Pharmaceutics International Incorporated | Compositions containing solid ibuprofen concentrates and methods of making solid ibuprofen concentrates |
| US20080014274A1 (en) * | 2006-07-14 | 2008-01-17 | Wyeth | Enhanced stability phenylephrine liquid compositions |
| US20110052679A1 (en) * | 2009-08-25 | 2011-03-03 | Pharmaceutics International, Inc. | Solid naproxen concentrates and related dosage forms |
-
2010
- 2010-01-19 CA CA2690488A patent/CA2690488C/en active Active
-
2011
- 2011-01-19 AU AU2011207061A patent/AU2011207061B2/en active Active
- 2011-01-19 ES ES11734283T patent/ES2880813T3/es active Active
- 2011-01-19 MX MX2012008300A patent/MX358636B/es active IP Right Grant
- 2011-01-19 EP EP11734283.2A patent/EP2525789B1/en active Active
- 2011-01-19 HU HUE11734283A patent/HUE055771T2/hu unknown
- 2011-01-19 WO PCT/CA2011/000059 patent/WO2011088553A1/en not_active Ceased
- 2011-01-19 PL PL11734283T patent/PL2525789T3/pl unknown
- 2011-01-19 DK DK11734283.2T patent/DK2525789T3/da active
- 2011-01-19 JP JP2012549215A patent/JP5975884B2/ja active Active
- 2011-01-19 PT PT117342832T patent/PT2525789T/pt unknown
- 2011-01-19 US US13/574,159 patent/US9480667B2/en active Active
- 2011-01-19 EP EP21177143.1A patent/EP3909567B1/en active Active
- 2011-01-19 SI SI201131992T patent/SI2525789T1/sl unknown
-
2016
- 2016-01-18 JP JP2016007253A patent/JP2016094462A/ja active Pending
- 2016-10-05 US US15/285,968 patent/US10463637B2/en active Active
-
2019
- 2019-09-26 US US16/583,903 patent/US11896566B2/en active Active
-
2023
- 2023-12-29 US US18/400,069 patent/US12605348B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3909567A1 (en) | 2021-11-17 |
| WO2011088553A1 (en) | 2011-07-28 |
| US20200046662A1 (en) | 2020-02-13 |
| US20130011470A1 (en) | 2013-01-10 |
| PT2525789T (pt) | 2021-07-19 |
| US9480667B2 (en) | 2016-11-01 |
| JP5975884B2 (ja) | 2016-08-23 |
| EP2525789A1 (en) | 2012-11-28 |
| CA2690488A1 (en) | 2011-07-19 |
| US10463637B2 (en) | 2019-11-05 |
| EP2525789A4 (en) | 2014-04-30 |
| MX358636B (es) | 2018-08-29 |
| PL2525789T3 (pl) | 2022-01-03 |
| US12605348B2 (en) | 2026-04-21 |
| SI2525789T1 (sl) | 2021-12-31 |
| US20240139132A1 (en) | 2024-05-02 |
| EP2525789B1 (en) | 2021-06-02 |
| HUE055771T2 (hu) | 2021-12-28 |
| ES2880813T3 (es) | 2021-11-25 |
| JP2013517304A (ja) | 2013-05-16 |
| MX2012008300A (es) | 2012-11-23 |
| US20170020832A1 (en) | 2017-01-26 |
| US11896566B2 (en) | 2024-02-13 |
| AU2011207061A1 (en) | 2012-07-26 |
| DK2525789T3 (da) | 2021-07-19 |
| AU2011207061B2 (en) | 2015-05-28 |
| EP3909567B1 (en) | 2026-04-29 |
| JP2016094462A (ja) | 2016-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 15TH ANNIV.) - STANDARD Year of fee payment: 15 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250110 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20250110 |