CA2684578A1 - Chimeric antigens - Google Patents
Chimeric antigens Download PDFInfo
- Publication number
- CA2684578A1 CA2684578A1 CA002684578A CA2684578A CA2684578A1 CA 2684578 A1 CA2684578 A1 CA 2684578A1 CA 002684578 A CA002684578 A CA 002684578A CA 2684578 A CA2684578 A CA 2684578A CA 2684578 A1 CA2684578 A1 CA 2684578A1
- Authority
- CA
- Canada
- Prior art keywords
- polypeptide
- rsv
- protein
- chimeric
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- C07K2319/00—Fusion polypeptide
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (3)
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| US89620107P | 2007-03-21 | 2007-03-21 | |
| US60/896,201 | 2007-03-21 | ||
| PCT/IB2008/001286 WO2008114149A2 (en) | 2007-03-21 | 2008-03-20 | Chimeric antigens |
Publications (1)
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| CA2684578A1 true CA2684578A1 (en) | 2008-09-25 |
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| CA002684578A Abandoned CA2684578A1 (en) | 2007-03-21 | 2008-03-20 | Chimeric antigens |
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| EP (1) | EP2181121A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010522540A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2684578A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008114149A2 (cg-RX-API-DMAC7.html) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160000902A1 (en) * | 2003-07-11 | 2016-01-07 | Novavax, Inc. | Combination vaccine for respiratory syncytial virus and influenza |
| DK2347775T3 (da) | 2005-12-13 | 2020-07-13 | Harvard College | Skabeloner til celletransplantation |
| WO2009002401A2 (en) | 2007-06-21 | 2008-12-31 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
| EP4206231A1 (en) | 2007-12-24 | 2023-07-05 | ID Biomedical Corporation of Quebec | Recombinant rsv antigens |
| US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
| US10328133B2 (en) | 2008-02-13 | 2019-06-25 | President And Fellows Of Harvard College | Continuous cell programming devices |
| EP3718566B1 (en) * | 2008-12-09 | 2024-06-12 | Novavax, Inc. | Modified rsv f proteins and methods of their use |
| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| HRP20160798T1 (hr) | 2009-06-24 | 2016-08-12 | Glaxosmithkline Biologicals S.A. | Rekombinantni antigeni iz rsv |
| AU2010264686A1 (en) | 2009-06-24 | 2012-01-19 | Glaxosmithkline Biologicals S.A. | Vaccine |
| CN102639147B (zh) | 2009-07-15 | 2015-11-25 | 诺华股份有限公司 | Rsv f 蛋白组合物和其制作方法 |
| WO2011007961A2 (en) * | 2009-07-17 | 2011-01-20 | Industry Academic Cooperation Foundation, Hallym University | Immunostimulatory compositions comprising liposome-encapsulated oligonucleotides and epitpoes |
| JP5926180B2 (ja) | 2009-07-31 | 2016-05-25 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 寛容原性療法のための細胞のプログラミングの方法 |
| AU2010279492B2 (en) * | 2009-08-04 | 2015-04-09 | The Government Of The United States Of America, As Represented By The Secretary, Department Of The Health And Human Services, Centers For Disease Control And Prevention | Anti-RSV immunogens and methods of immunization |
| CA2799934C (en) | 2010-07-07 | 2020-01-28 | Artificial Cell Technologies, Inc. | Respiratory syncytial virus antigenic compositions and methods |
| EP2624873B1 (en) | 2010-10-06 | 2019-12-04 | President and Fellows of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
| US20140024076A1 (en) * | 2011-01-28 | 2014-01-23 | Medimmune, Llc. | Expression Of Soluble Viral Fusion Glycoproteins In Mammalian Cells |
| EA034702B1 (ru) * | 2011-04-26 | 2020-03-10 | Молекулар Экспресс, Инк. | Липосомные композиции |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| ES2685327T3 (es) | 2011-04-28 | 2018-10-08 | President And Fellows Of Harvard College | Armazones tridimensionales macroscópicos preformados inyectables para administración mínimamente invasiva |
| SG194755A1 (en) | 2011-05-13 | 2013-12-30 | Novartis Ag | Pre-fusion rsv f antigens |
| EP2714073B1 (en) | 2011-06-03 | 2021-03-10 | President and Fellows of Harvard College | In situ antigen-generating cancer vaccine |
| ES2395677B1 (es) * | 2011-07-29 | 2013-12-26 | Instituto De Salud Carlos Iii | Proteína F del VRSH en conformación pre-fusión estabilizada y anticuerpos neutralizantes específicos frente a la misma. |
| JP6085886B2 (ja) | 2011-08-29 | 2017-03-01 | 国立大学法人徳島大学 | Ｒｓｖ粘膜ワクチン |
| SG11201400999VA (en) * | 2011-09-30 | 2014-07-30 | Novavax Inc | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
| JP2015514132A (ja) * | 2012-04-10 | 2015-05-18 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ヒト呼吸器合胞体ウイルスコンセンサス抗原、核酸構築物、およびそれらから作製されるワクチン、ならびにその使用方法 |
| LT2838515T (lt) | 2012-04-16 | 2020-03-10 | President And Fellows Of Harvard College | Mezoporinės silico dioksido kompozicijos, skirtos imuninio atsako moduliavimui |
| PT2879702T (pt) * | 2012-08-01 | 2020-02-04 | Bavarian Nordic As | Vacina para o vírus sincicial respiratório (rsv) de vírus vaccinia modificado recombinante ankara (mva) |
| EP3656396A1 (en) * | 2012-08-01 | 2020-05-27 | Bavarian Nordic A/S | Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine |
| US20140037680A1 (en) | 2012-08-06 | 2014-02-06 | Glaxosmithkline Biologicals, S.A. | Novel method |
| SG11201500573RA (en) | 2012-08-06 | 2015-02-27 | Glaxosmithkline Biolog Sa | Method for eliciting in infants an immune response against rsv and b. pertussis |
| SG11201506197TA (en) * | 2013-02-11 | 2015-09-29 | Novavax Inc | Combination vaccine for respiratory syncytial virus and influenza |
| EP3030260A1 (en) | 2013-08-05 | 2016-06-15 | GlaxoSmithKline Biologicals S.A. | Combination immunogenic compositions |
| WO2015168379A2 (en) | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
| JP6664338B2 (ja) | 2014-06-13 | 2020-03-13 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組合せ物 |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| CN107708756A (zh) | 2015-04-10 | 2018-02-16 | 哈佛学院院长等 | 免疫细胞捕获装置及其制备和使用方法 |
| KR102758377B1 (ko) | 2015-09-03 | 2025-01-23 | 노바백스, 인코포레이티드 | 개선된 안정성 및 면역원성을 갖는 백신 조성물 |
| KR102136678B1 (ko) | 2015-12-23 | 2020-07-22 | 화이자 인코포레이티드 | Rsv f 단백질 돌연변이체 |
| CN115487351A (zh) | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
| ES3032115T3 (en) | 2016-07-13 | 2025-07-15 | Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
| WO2018026884A1 (en) | 2016-08-02 | 2018-02-08 | President And Fellows Of Harvard College | Biomaterials for modulating immune responses |
| WO2018026941A1 (en) | 2016-08-03 | 2018-02-08 | Lonza Walkersville, Inc. | Method of detecting an endotoxin using limulus amebocyte lysate substantially free of coagulogen |
| GB201620968D0 (en) | 2016-12-09 | 2017-01-25 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
| KR102545029B1 (ko) * | 2017-01-11 | 2023-06-19 | 론자 워커스빌 아이엔씨. | 맑고 밝게된 무-코아굴로겐 리물루스 아메바세포 용해물 |
| JP7317796B2 (ja) | 2017-07-24 | 2023-07-31 | ノババックス，インコーポレイテッド | 呼吸器疾患を治療するための方法および組成物 |
| CA3079048A1 (en) | 2017-10-16 | 2019-04-25 | Glaxosmithkline Biologicals Sa | Adenoviral vectors with two expression cassettes encoding rsv antigenic proteins or fragments thereof |
| WO2019076892A1 (en) | 2017-10-16 | 2019-04-25 | Glaxosmithkline Biologicals Sa | ENHANCED PROMOTER |
| WO2019076880A1 (en) | 2017-10-16 | 2019-04-25 | Glaxosmithkline Biologicals Sa | SIMIENS ADENOVIRAL VECTORS COMPRISING TWO EXPRESSION CASSETTES |
| WO2019108541A1 (en) * | 2017-11-28 | 2019-06-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant rsv g proteins and their use |
| IL305911B2 (en) | 2018-03-19 | 2025-01-01 | Novavax Inc | Multifunctional nanoparticle influenza vaccines |
| EP3807298A1 (en) | 2018-06-12 | 2021-04-21 | GlaxoSmithKline Biologicals S.A. | Adenovirus polynucleotides and polypeptides |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| KR102725189B1 (ko) | 2018-11-01 | 2024-10-31 | 에스케이바이오사이언스(주) | 재조합 호흡기 세포융합 바이러스 f 단백질 및 이를 포함하는 백신 조성물 |
| KR102679227B1 (ko) | 2019-02-28 | 2024-06-28 | 케이엠 바이올로직스 가부시키가이샤 | Rsv f/g 키메라 백신 |
| CN114993784B (zh) * | 2022-05-27 | 2025-07-29 | 重庆医科大学 | 一种乙肝病毒颗粒裂解液及其制备与应用 |
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| DE69828801T2 (de) * | 1997-09-19 | 2005-07-14 | Wyeth Holdings Corp. | Peptide, abgeleitet vom angelagerten g-protein des respiratory syncytial virus |
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| EP2181121A4 (en) | 2012-07-11 |
| WO2008114149A2 (en) | 2008-09-25 |
| EP2181121A2 (en) | 2010-05-05 |
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| JP2010522540A (ja) | 2010-07-08 |
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