CA2683752A1 - Method of inducing neutralizing antibodies to human immunodeficiency virus - Google Patents
Method of inducing neutralizing antibodies to human immunodeficiency virus Download PDFInfo
- Publication number
- CA2683752A1 CA2683752A1 CA002683752A CA2683752A CA2683752A1 CA 2683752 A1 CA2683752 A1 CA 2683752A1 CA 002683752 A CA002683752 A CA 002683752A CA 2683752 A CA2683752 A CA 2683752A CA 2683752 A1 CA2683752 A1 CA 2683752A1
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- Prior art keywords
- hiv
- peptide
- liposome
- mper
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/785,077 | 2007-04-13 | ||
| US11/785,077 US9402893B2 (en) | 2005-04-12 | 2007-04-13 | Liposome-peptide conjugate and method of using same to induce production of anti-HIV antibodies |
| US11/812,992 US20080057075A1 (en) | 2005-04-12 | 2007-06-22 | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| US11/812,992 | 2007-06-22 | ||
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| EP1868651A4 (en) | 2005-04-12 | 2010-10-06 | Univ Duke | METHOD FOR INDUCTION OF NEUTRALIZING ANTIBODIES TO THE HIV VIRUS |
| WO2008127651A1 (en) | 2007-04-13 | 2008-10-23 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| US20120070488A1 (en) * | 2007-09-28 | 2012-03-22 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| EP2331104A4 (en) * | 2008-09-05 | 2012-10-17 | Univ Duke | METHOD FOR INDUCING AN ANTIVIRAL IMMUNE RESPONSE |
| EP2413951A4 (en) * | 2009-04-03 | 2015-05-20 | Univ Duke | FORMULATION FOR GENERATING A WIDE REACTIVE NEUTRALIZATION OF HIV ANTIBODIES |
| WO2011046623A2 (en) * | 2009-10-16 | 2011-04-21 | Duke University | Hiv-1 antibodies |
| JP2013520498A (ja) | 2010-02-25 | 2013-06-06 | デューク ユニバーシティー | 防御的抗ｈｉｖ−１抗体の産生を誘導する方法 |
| WO2013134293A1 (en) * | 2012-03-05 | 2013-09-12 | Duke University | Vaccine formulation |
| US10076567B2 (en) | 2013-09-27 | 2018-09-18 | Duke University | MPER-liposome conjugates and uses thereof |
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| US5831034A (en) | 1987-11-13 | 1998-11-03 | Hermann Katinger | Human monoclonal anti-HIV-I-antibodies |
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| DE69311764T2 (de) | 1992-05-14 | 1998-02-05 | Polymun Scient Immunbio Forsch | Peptide, die Antikörper induzieren, die genetisch divergierende HIV-1 Isolationen neutralisieren |
| JPH09500358A (ja) | 1993-03-11 | 1997-01-14 | ザ ユニバーシティ オブ サザンカリフォルニア | 免疫感染性クラスター・ウイルス感染のための治療的戦略 |
| DE69433013T2 (de) | 1993-05-27 | 2004-06-03 | Entremed, Inc. | Zubereitungen und verfahren für die behandlung von krebs und hyperproliferierenden krankheiten |
| DE69418334T2 (de) * | 1993-08-06 | 2000-01-27 | Opperbas Holding B.V., Amsterdam | Verfahren zur hohen beladung von vesikeln mit biopolymeren substanzen |
| CZ287808B6 (en) | 1993-09-11 | 2001-02-14 | Polymun Scient Immunbio Forsch | Peptides inducing formation of antibodies, process of their preparation, their use and antibody induced thereby and acting against genetically divergent HIV-1 strains |
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| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
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| WO1996040243A1 (en) * | 1995-06-07 | 1996-12-19 | U.S. Department Of The Army | Liposomes containing human immunodeficiency virus glycoprotein and methods for use thereof |
| US5910306A (en) | 1996-11-14 | 1999-06-08 | The United States Of America As Represented By The Secretary Of The Army | Transdermal delivery system for antigen |
| US5901306A (en) * | 1997-06-23 | 1999-05-04 | Sun Microsystems, Inc. | Method and apparatus for reducing a computational result to the range boundaries of a signed 8-bit integer in case of overflow |
| US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
| US6300308B1 (en) | 1997-12-31 | 2001-10-09 | Board Of Regents, The University Of Texas System | Methods and compositions for inducing autoimmunity in the treatment of cancers |
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| US7455833B2 (en) | 2002-07-15 | 2008-11-25 | Board Of Regents, The University Of Texas System | Methods and compositions for treating viral infections using antibodies and immunoconjugates to aminophospholipids |
| US7384909B2 (en) | 2002-07-15 | 2008-06-10 | Board Of Regents, The University Of Texas System | Anti-viral treatment methods using phosphatidylethanolamine-binding peptides linked to anti-viral agents |
| US20040131622A1 (en) | 2002-07-15 | 2004-07-08 | Board Of Regents | Combinations and kits for treating viral infections using immunoconjugates to aminophospholipids |
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| US7611704B2 (en) | 2002-07-15 | 2009-11-03 | Board Of Regents, The University Of Texas System | Compositions and methods for treating viral infections using antibodies and immunoconjugates to aminophospholipids |
| US7790159B2 (en) | 2002-07-15 | 2010-09-07 | Board Of Regents, The University Of Texas System | Methods, combinations and kits for treating viral infections using immunoconjugates and antibodies to aminophospholipids |
| US7678386B2 (en) | 2002-07-15 | 2010-03-16 | Board Of Regents The University Of Texas | Liposomes coated with selected antibodies that bind to aminophospholipids |
| MXPA05000652A (es) | 2002-07-15 | 2005-08-19 | Univ Texas | Anticuerpos seleccionados y peptidos de duramicina que se enlazan a fosfolipidos anionicos y aminofosfolipidos y sus usos en el tratamiento de infecciones virales y del cancer. |
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| WO2005111079A2 (en) | 2004-05-14 | 2005-11-24 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | Hiv vaccine immunogens and immunization strategies to elicit broadly-neutralizing anti-hiv-1 antibodies against the membrane proximal domain of hiv gp41 |
| US20080057075A1 (en) | 2005-04-12 | 2008-03-06 | Haynes Barton F | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| EP1868651A4 (en) * | 2005-04-12 | 2010-10-06 | Univ Duke | METHOD FOR INDUCTION OF NEUTRALIZING ANTIBODIES TO THE HIV VIRUS |
| WO2008127651A1 (en) | 2007-04-13 | 2008-10-23 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| CN101678091A (zh) | 2007-05-24 | 2010-03-24 | 葛兰素史密丝克莱恩生物有限公司 | 冷冻干燥的抗原组合物 |
| US20120070488A1 (en) | 2007-09-28 | 2012-03-22 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| WO2009111304A2 (en) | 2008-02-29 | 2009-09-11 | President And Fellows Of Harvard College | A fusion-intermediate state of hiv-1 gp41 targeted by broadly neutralizing antibodies |
| SMT202000101T1 (it) | 2008-10-10 | 2020-03-13 | Childrens Medical Center | Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente |
| EP2413951A4 (en) | 2009-04-03 | 2015-05-20 | Univ Duke | FORMULATION FOR GENERATING A WIDE REACTIVE NEUTRALIZATION OF HIV ANTIBODIES |
| EP2413905A4 (en) | 2009-04-03 | 2012-10-31 | Univ Duke | FORMULATION |
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| US8956627B2 (en) | 2015-02-17 |
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| EP2139516A1 (en) | 2010-01-06 |
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| WO2008127651A1 (en) | 2008-10-23 |
| JP2010523676A (ja) | 2010-07-15 |
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