DE60329461D1 - Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzieren - Google Patents
Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzierenInfo
- Publication number
- DE60329461D1 DE60329461D1 DE60329461T DE60329461T DE60329461D1 DE 60329461 D1 DE60329461 D1 DE 60329461D1 DE 60329461 T DE60329461 T DE 60329461T DE 60329461 T DE60329461 T DE 60329461T DE 60329461 D1 DE60329461 D1 DE 60329461D1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- relates
- neutralizing
- fragments
- hiv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003472 neutralizing effect Effects 0.000 title abstract 3
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4216—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig
- C07K16/4225—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig against anti-HIV Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02001250 | 2002-01-17 | ||
| PCT/EP2003/000455 WO2003059953A2 (en) | 2002-01-17 | 2003-01-17 | Anti-idiotypic antibody inducing hiv-1 neutralizing antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60329461D1 true DE60329461D1 (de) | 2009-11-12 |
Family
ID=8185289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60329461T Expired - Lifetime DE60329461D1 (de) | 2002-01-17 | 2003-01-17 | Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzieren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7625566B2 (de) |
| EP (1) | EP1465928B1 (de) |
| JP (1) | JP4495969B2 (de) |
| AT (1) | ATE444310T1 (de) |
| AU (1) | AU2003214044B8 (de) |
| CA (1) | CA2473163C (de) |
| DE (1) | DE60329461D1 (de) |
| WO (1) | WO2003059953A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1868651A4 (de) | 2005-04-12 | 2010-10-06 | Univ Duke | Verfahren zur induktion von neutralisierenden antikörpern gegen das hiv-virus |
| ITTO20070066A1 (it) * | 2007-01-30 | 2008-07-31 | Pomona Biotechnologies Llc | Anticorpi monoclonali anti-idiotipo mimotopi dell'antigene gp 120 di hiv |
| CA2683752A1 (en) | 2007-04-13 | 2008-10-23 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| ITTO20080204A1 (it) * | 2008-03-17 | 2009-09-18 | Pomona Biotechnologies Llc | Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a |
| ITTO20080398A1 (it) * | 2008-05-27 | 2009-11-28 | Pomona Biotechnologies Llc | Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1 |
| ITTO20080964A1 (it) | 2008-12-22 | 2010-06-23 | Natimab Therapeutics S R L | Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv |
| IT1395961B1 (it) | 2009-06-01 | 2012-11-02 | Pomona Biotechnologies Llc | Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv) |
| IN2015DN01483A (de) * | 2012-08-08 | 2015-07-03 | Network Immunology Inc | |
| US10076567B2 (en) | 2013-09-27 | 2018-09-18 | Duke University | MPER-liposome conjugates and uses thereof |
| WO2018017797A1 (en) * | 2016-07-22 | 2018-01-25 | Georgia State Universtiy Research Foundation | Monoclonal antibodies to b virus and their use for identification of b virus specific reactive peptides |
| JPWO2021065846A1 (de) * | 2019-09-30 | 2021-04-08 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1025692A (en) | 1991-02-06 | 1992-08-13 | Ciba-Geigy Ag | Novel chimeric antiidiotypic monoclonal antibodies |
| IE920785A1 (en) * | 1991-03-11 | 1992-09-23 | Idec Pharma Corp | Methods for selecting antibody reagents; anti-idiotype¹antibodies; and aids vaccine formulations |
| ES2053413T3 (es) | 1992-05-14 | 1997-11-16 | Polymun Scient Immunbio Forsch | Peptidos que inducen anticuerpos que neutralizan aislados de vih-1 geneticamente divergentes. |
| US6099846A (en) | 1992-10-14 | 2000-08-08 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of B cell lymphoma and tumor resistance using idiotype/cytokine conjugates |
| JP2000507917A (ja) * | 1995-11-02 | 2000-06-27 | シェーリング コーポレイション | 持続的低用量サイトカイン注入治療 |
| ATE303161T1 (de) * | 1996-03-20 | 2005-09-15 | Immunomedics Inc | Humanisierung von anti-carcinoembryonalen antigen anti-idiotypischen antikörper und dessen verwendung als tumorvakzin und zur markierung |
| CA2745736C (en) | 1996-10-23 | 2016-11-22 | The Trustees Of The University Of Pennsylvania | Immunotherapy and improved vaccines |
-
2003
- 2003-01-17 WO PCT/EP2003/000455 patent/WO2003059953A2/en active Application Filing
- 2003-01-17 DE DE60329461T patent/DE60329461D1/de not_active Expired - Lifetime
- 2003-01-17 US US10/501,726 patent/US7625566B2/en not_active Expired - Fee Related
- 2003-01-17 CA CA2473163A patent/CA2473163C/en not_active Expired - Fee Related
- 2003-01-17 AT AT03709690T patent/ATE444310T1/de active
- 2003-01-17 EP EP03709690A patent/EP1465928B1/de not_active Expired - Lifetime
- 2003-01-17 AU AU2003214044A patent/AU2003214044B8/en not_active Ceased
- 2003-01-17 JP JP2003560055A patent/JP4495969B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003059953B1 (en) | 2004-02-26 |
| ATE444310T1 (de) | 2009-10-15 |
| AU2003214044A1 (en) | 2003-07-30 |
| AU2003214044B2 (en) | 2008-06-26 |
| CA2473163A1 (en) | 2003-07-24 |
| US7625566B2 (en) | 2009-12-01 |
| JP2005517685A (ja) | 2005-06-16 |
| WO2003059953A3 (en) | 2003-12-18 |
| JP4495969B2 (ja) | 2010-07-07 |
| WO2003059953A2 (en) | 2003-07-24 |
| AU2003214044B8 (en) | 2008-11-13 |
| EP1465928B1 (de) | 2009-09-30 |
| CA2473163C (en) | 2011-12-06 |
| US20050080240A1 (en) | 2005-04-14 |
| EP1465928A2 (de) | 2004-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |