CA2683207A1 - Determination of melting temperatures by equation-less methods - Google Patents

Determination of melting temperatures by equation-less methods Download PDF

Info

Publication number
CA2683207A1
CA2683207A1 CA2683207A CA2683207A CA2683207A1 CA 2683207 A1 CA2683207 A1 CA 2683207A1 CA 2683207 A CA2683207 A CA 2683207A CA 2683207 A CA2683207 A CA 2683207A CA 2683207 A1 CA2683207 A1 CA 2683207A1
Authority
CA
Canada
Prior art keywords
parameter
derivative values
maximum value
values
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2683207A
Other languages
English (en)
French (fr)
Inventor
Ronald T. Kurnik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2683207A1 publication Critical patent/CA2683207A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/18—Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pure & Applied Mathematics (AREA)
  • Computational Mathematics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Mathematical Analysis (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Probability & Statistics with Applications (AREA)
  • Algebra (AREA)
  • Operations Research (AREA)
  • Databases & Information Systems (AREA)
  • Software Systems (AREA)
  • Evolutionary Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2683207A 2008-10-17 2009-10-16 Determination of melting temperatures by equation-less methods Abandoned CA2683207A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/253,676 2008-10-17
US12/253,676 US8170804B2 (en) 2008-10-17 2008-10-17 Determination of melting temperatures of DNA

Publications (1)

Publication Number Publication Date
CA2683207A1 true CA2683207A1 (en) 2010-04-17

Family

ID=42046255

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2683207A Abandoned CA2683207A1 (en) 2008-10-17 2009-10-16 Determination of melting temperatures by equation-less methods

Country Status (5)

Country Link
US (2) US8170804B2 (cg-RX-API-DMAC10.html)
EP (1) EP2180418B1 (cg-RX-API-DMAC10.html)
JP (1) JP5642954B2 (cg-RX-API-DMAC10.html)
CN (1) CN101782940B (cg-RX-API-DMAC10.html)
CA (1) CA2683207A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102607495B (zh) * 2012-02-22 2014-05-14 西安建筑科技大学 一种保温罐外壁保温材料厚度的确定方法
CN102591204A (zh) * 2012-02-27 2012-07-18 哈尔滨海太精密量仪有限公司 一种高斯系统的实现方法
JP2015191132A (ja) * 2014-03-28 2015-11-02 株式会社Ｓｃｒｅｅｎホールディングス 輝度分布測定装置、描画装置および輝度分布測定方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739357D1 (de) * 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
JP2002088143A (ja) * 2000-07-14 2002-03-27 Toray Ind Inc 成形用ポリエステルフィルム
US7387887B2 (en) * 2004-04-20 2008-06-17 University Of Utah Research Foundation Nucleic acid melting analysis with saturation dyes
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US8068992B2 (en) * 2005-09-20 2011-11-29 University Of Utah Research Foundation Melting curve analysis with exponential background subtraction
JP5239853B2 (ja) * 2006-03-13 2013-07-17 和光純薬工業株式会社 変異遺伝子の検出方法
JP5286261B2 (ja) * 2006-07-17 2013-09-11 ブランディーズ・ユニバーシティ 特殊化オリゴヌクレオチドならびに核酸の増幅および検出でのその使用
US20090037117A1 (en) * 2007-01-30 2009-02-05 Applera Corporation Differential Dissociation and Melting Curve Peak Detection
US8606527B2 (en) * 2009-02-27 2013-12-10 Bio-Rad Laboratories, Inc. SNP detection by melt curve clustering

Also Published As

Publication number Publication date
EP2180418B1 (en) 2023-08-30
EP2180418A2 (en) 2010-04-28
EP2180418A3 (en) 2017-11-08
HK1142419A1 (en) 2010-12-03
US8340918B2 (en) 2012-12-25
US20120197537A1 (en) 2012-08-02
CN101782940A (zh) 2010-07-21
JP5642954B2 (ja) 2014-12-17
US20100100332A1 (en) 2010-04-22
JP2010113711A (ja) 2010-05-20
US8170804B2 (en) 2012-05-01
CN101782940B (zh) 2014-06-11

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20141015

FZDE Discontinued

Effective date: 20180712