CA2680771C - Use of 1-phenyl-3-dimethylaminopropane compounds for treating neuropathy pain - Google Patents

Use of 1-phenyl-3-dimethylaminopropane compounds for treating neuropathy pain Download PDF

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Publication number
CA2680771C
CA2680771C CA2680771A CA2680771A CA2680771C CA 2680771 C CA2680771 C CA 2680771C CA 2680771 A CA2680771 A CA 2680771A CA 2680771 A CA2680771 A CA 2680771A CA 2680771 C CA2680771 C CA 2680771C
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CA
Canada
Prior art keywords
pain
dimethylamino
acid
diabetic
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2680771A
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English (en)
French (fr)
Other versions
CA2680771A1 (en
Inventor
Thomas Christoph
Babette-Yvonne Koegel
Elmar Friderichs
Muriel Meen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39345501&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2680771(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of CA2680771A1 publication Critical patent/CA2680771A1/en
Application granted granted Critical
Publication of CA2680771C publication Critical patent/CA2680771C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA2680771A 2007-03-12 2008-03-10 Use of 1-phenyl-3-dimethylaminopropane compounds for treating neuropathy pain Active CA2680771C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102007012165A DE102007012165A1 (de) 2007-03-12 2007-03-12 Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
DE102007012165.4 2007-03-12
PCT/EP2008/001884 WO2008110323A1 (de) 2007-03-12 2008-03-10 Verwendung von 1-phenyl-3-dimethylamino-propanverbindungen zur therapie des neuropathieschmerzes

Publications (2)

Publication Number Publication Date
CA2680771A1 CA2680771A1 (en) 2008-09-18
CA2680771C true CA2680771C (en) 2015-11-17

Family

ID=39345501

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2680771A Active CA2680771C (en) 2007-03-12 2008-03-10 Use of 1-phenyl-3-dimethylaminopropane compounds for treating neuropathy pain

Country Status (13)

Country Link
US (2) US20080269326A1 (https=)
EP (1) EP2117525B1 (https=)
JP (5) JP2010520907A (https=)
CA (1) CA2680771C (https=)
CY (1) CY1115455T1 (https=)
DE (1) DE102007012165A1 (https=)
DK (1) DK2117525T3 (https=)
ES (1) ES2452830T3 (https=)
HR (1) HRP20140280T1 (https=)
PL (1) PL2117525T3 (https=)
PT (1) PT2117525E (https=)
SI (1) SI2117525T1 (https=)
WO (1) WO2008110323A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2582366T1 (sl) * 2010-06-15 2016-02-29 Gruenenthal Gmbh Farmacevtska kombinacija za zdravljenje bolečine
EP3597628A1 (en) * 2010-07-23 2020-01-22 Grünenthal GmbH Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
WO2012051246A1 (en) 2010-10-12 2012-04-19 Ratiopharm Gmbh Tapentadol hydrobromide and crystalline forms thereof
JP2019142972A (ja) * 2011-03-04 2019-08-29 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング タペンタドールの非経口的投与
RS56692B1 (sr) * 2011-03-04 2018-03-30 Gruenenthal Gmbh Polučvrsta vodena farmaceutska kompozicija koja sadrži tapentadol
CA2828635C (en) * 2011-03-04 2020-01-14 Grunenthal Gmbh Parenteral administration of tapentadol
KR101946790B1 (ko) 2011-03-04 2019-02-13 그뤼넨탈 게엠베하 경구 투여를 위한 타펜타돌의 수성 약제학적 제형
US20120309840A1 (en) 2011-04-05 2012-12-06 Gruenenthal Gmbh Treatment of Pain Associated with Trigeminal Neuralgia
RS58064B1 (sr) 2011-04-05 2019-02-28 Gruenenthal Gmbh Tapentadol za sprečavanje hronifikacije bola
LT3272343T (lt) 2011-04-29 2020-05-11 Grünenthal GmbH Tapentadolis, skirtas depresijos ir nerimo prevencijai ir gydymui
EP2736501B1 (en) * 2011-07-29 2017-12-20 Grünenthal GmbH Intrathecal or epidural administration of 3-[(1s,2s)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol
US8853393B2 (en) 2011-07-29 2014-10-07 Anhui New Star Pharmaceutical Development Co., Ltd. Intermediate for preparing tapentadol or analogues thereof
CN103159633B (zh) * 2012-07-06 2015-08-12 江苏恩华药业股份有限公司 他喷他多的制备方法及用于制备他喷他多的化合物
EP2808319A1 (en) 2013-05-31 2014-12-03 Arevipharma GmbH 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
EP3273953B1 (en) 2015-03-27 2019-01-02 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
CN109996533A (zh) 2016-09-23 2019-07-09 格吕伦塔尔有限公司 用于肠胃外施用他喷他多的稳定制剂
WO2018153947A1 (en) 2017-02-23 2018-08-30 Grünenthal GmbH Tapentadol as local anesthetic
CN114788814B (zh) * 2021-01-26 2023-10-13 浙江创新生物有限公司 一种高稳定性的注射用达托霉素组合物及其制备方法和其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
PT1562567T (pt) * 2002-11-22 2017-08-24 Gruenenthal Gmbh Combinação de analgésicos selecionados e inibidores da cox-ii
RU2442576C2 (ru) * 2006-04-28 2012-02-20 Грюненталь Гмбх Фармацевтическая комбинация, содержащая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и парацетамол

Also Published As

Publication number Publication date
US8536130B2 (en) 2013-09-17
JP6081337B2 (ja) 2017-02-15
DK2117525T3 (da) 2014-02-03
JP6745959B2 (ja) 2020-08-26
WO2008110323A1 (de) 2008-09-18
PL2117525T3 (pl) 2014-05-30
HRP20140280T1 (hr) 2014-04-25
PT2117525E (pt) 2014-02-14
JP2019196405A (ja) 2019-11-14
JP2010520907A (ja) 2010-06-17
CY1115455T1 (el) 2017-01-04
US20100311842A1 (en) 2010-12-09
JP2016056188A (ja) 2016-04-21
EP2117525A1 (de) 2009-11-18
US20080269326A1 (en) 2008-10-30
JP2018030886A (ja) 2018-03-01
ES2452830T3 (es) 2014-04-02
JP2013256540A (ja) 2013-12-26
SI2117525T1 (sl) 2014-03-31
CA2680771A1 (en) 2008-09-18
DE102007012165A1 (de) 2008-09-18
EP2117525B1 (de) 2013-12-25

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Publication Publication Date Title
CA2680771C (en) Use of 1-phenyl-3-dimethylaminopropane compounds for treating neuropathy pain
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DE10224107A1 (de) Kombination ausgewählter Opioide mit anderen Wirkstoffen zur Therapie der Harninkontinenz
US20180235909A1 (en) Use of 1-phenyl-3-dimethylaminopropane Compounds for Treating Rheumatoid Pain
EP3607943B1 (en) Tapentadol for use in treating pain associated with trigeminal neuralgia
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HK1224570A (en) Use of 1-phenyl-3-dimethylaminopropane compounds for treating rheumatoid pain
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