CA2677813A1 - Method of treating cell proliferative disorders using growth hormone secretagogues - Google Patents
Method of treating cell proliferative disorders using growth hormone secretagogues Download PDFInfo
- Publication number
- CA2677813A1 CA2677813A1 CA002677813A CA2677813A CA2677813A1 CA 2677813 A1 CA2677813 A1 CA 2677813A1 CA 002677813 A CA002677813 A CA 002677813A CA 2677813 A CA2677813 A CA 2677813A CA 2677813 A1 CA2677813 A1 CA 2677813A1
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- Prior art keywords
- alkyl
- aryl
- independently
- hydrogen
- hetaryl
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- 239000003324 growth hormone secretagogue Substances 0.000 title claims abstract description 83
- 238000000034 method Methods 0.000 title claims abstract description 43
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- 125000001072 heteroaryl group Chemical group 0.000 claims description 101
- -1 amino, hydroxyl Chemical group 0.000 claims description 72
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- 150000002367 halogens Chemical group 0.000 claims description 55
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Landscapes
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- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90160907P | 2007-02-13 | 2007-02-13 | |
| US60/901,609 | 2007-02-13 | ||
| PCT/US2008/001748 WO2008100448A2 (en) | 2007-02-13 | 2008-02-08 | Method of treating cell proliferative disorders using growth hormone secretagogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2677813A1 true CA2677813A1 (en) | 2008-08-21 |
Family
ID=39690677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002677813A Abandoned CA2677813A1 (en) | 2007-02-13 | 2008-02-08 | Method of treating cell proliferative disorders using growth hormone secretagogues |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080207640A1 (enExample) |
| EP (1) | EP2134341B1 (enExample) |
| JP (1) | JP2010518158A (enExample) |
| KR (1) | KR20090112720A (enExample) |
| CN (1) | CN101686966A (enExample) |
| AU (1) | AU2008216789A1 (enExample) |
| CA (1) | CA2677813A1 (enExample) |
| EA (1) | EA200970764A1 (enExample) |
| IL (1) | IL200367A0 (enExample) |
| MX (1) | MX2009008561A (enExample) |
| TW (1) | TWI450719B (enExample) |
| WO (1) | WO2008100448A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2012141061A (ru) * | 2010-02-26 | 2014-04-10 | Раквалиа Фарма Инк. | Агонист рецептора грелина для лечения кахексии |
| JO3353B1 (ar) * | 2012-04-20 | 2019-03-13 | Ono Pharmaceutical Co | شكل صلب معزول من أحادي هيدروكلوريد أناموريلين بنسبة مولارية منخفضة من الكلوريد: أناموريلين ومحتوى منخفض من مذيب عضوي متبقي |
| ES2675215T3 (es) | 2013-02-08 | 2018-07-09 | General Mills, Inc. | Productos alimentarios reducidos en sodio |
| DK3188599T3 (da) * | 2014-09-04 | 2019-11-25 | Helsinn Healthcare Sa | Medicinske behandlinger baseret på anamorelin |
| US12084472B2 (en) | 2015-12-18 | 2024-09-10 | Ardelyx, Inc. | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists |
| TWI773657B (zh) | 2015-12-18 | 2022-08-11 | 美商亞德利克斯公司 | 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物 |
| CN115569120A (zh) | 2019-08-30 | 2023-01-06 | 赫尔森保健股份公司 | 具有改善稳定性的阿拉莫林片剂的生产方法 |
| CN115151540A (zh) | 2019-12-02 | 2022-10-04 | 风暴治疗有限公司 | 作为mettl3抑制剂的多杂环化合物 |
| WO2025104491A1 (en) | 2023-11-14 | 2025-05-22 | Mindset Pharma Inc. | Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto |
Family Cites Families (19)
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| UA42747C2 (uk) * | 1993-12-23 | 2001-11-15 | Ново Нордіск А/С | Похідні пептиду,фармацевтична композиція та спосіб стимулювання секреції гормону росту |
| PL327227A1 (en) * | 1995-12-22 | 1998-12-07 | Novo Nordisk As | Compounds exhibiting growth hormone liberating properties |
| DE69734215T2 (de) * | 1996-07-22 | 2006-06-29 | Novo Nordisk A/S | Verbindungen mit Wachstumshormon-freisetzenden Eigenschaften |
| US6566334B1 (en) * | 1997-02-06 | 2003-05-20 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Short amphipathic peptides with activity against bacteria and intracellular pathogens |
| US6286927B1 (en) * | 1997-12-25 | 2001-09-11 | Canon Kabushiki Kaisha | Ink jet element substrate and ink jet head that employs the substrate, and ink jet apparatus on which the head is mounted |
| US6494563B2 (en) * | 1997-12-25 | 2002-12-17 | Canon Kabushiki Kaisha | Ink jet element substrate and ink jet head that employs the substrate, and ink jet apparatus on which the head is mounted |
| US6083908A (en) * | 1998-01-16 | 2000-07-04 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| US6303620B1 (en) * | 1998-05-11 | 2001-10-16 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| US6124263A (en) | 1998-11-16 | 2000-09-26 | Asta Medica Ag | Treatment of tumors by administration of growth hormone releasing compounds and their antagonists |
| US6919315B1 (en) | 1998-06-30 | 2005-07-19 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| US6566337B1 (en) * | 1998-11-03 | 2003-05-20 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| UA73530C2 (uk) | 1999-11-10 | 2005-08-15 | Ново Нордіск А/С | Сполука з властивостями вивільнювати гормон росту |
| ATE446758T1 (de) * | 2000-05-31 | 2009-11-15 | Pfizer Prod Inc | Verwendung von wachstumshormonsekretagoga zur förderung der beweglichkeit des verdauungstrakts |
| JP2003535144A (ja) * | 2000-06-07 | 2003-11-25 | アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ | 多能性造血幹細胞の流動を刺激するヒト成長ホルモン |
| WO2002079146A2 (en) * | 2001-03-02 | 2002-10-10 | Bristol-Myers Squibb Company | Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same |
| EP1312363A1 (en) * | 2001-09-28 | 2003-05-21 | Pfizer Products Inc. | Methods of treatment and kits comprising a growth hormone secretagogue |
| US7491695B2 (en) | 2003-06-18 | 2009-02-17 | Tranzyme Pharma Inc. | Methods of using macrocyclic modulators of the ghrelin receptor |
| EP1735055A1 (en) * | 2004-03-30 | 2006-12-27 | Sapphire Therapeutics, Inc. | Method of reducing c-reactive protein using growth hormone secretagogues |
| CA2677399C (en) * | 2007-02-09 | 2016-09-13 | Tranzyme Pharma, Inc. | Macrocyclic ghrelin receptor modulators and methods of using the same |
-
2008
- 2008-02-08 CA CA002677813A patent/CA2677813A1/en not_active Abandoned
- 2008-02-08 CN CN200880011801A patent/CN101686966A/zh active Pending
- 2008-02-08 JP JP2009549593A patent/JP2010518158A/ja active Pending
- 2008-02-08 AU AU2008216789A patent/AU2008216789A1/en not_active Abandoned
- 2008-02-08 WO PCT/US2008/001748 patent/WO2008100448A2/en not_active Ceased
- 2008-02-08 MX MX2009008561A patent/MX2009008561A/es not_active Application Discontinuation
- 2008-02-08 KR KR1020097017491A patent/KR20090112720A/ko not_active Ceased
- 2008-02-08 EA EA200970764A patent/EA200970764A1/ru unknown
- 2008-02-08 EP EP08725389.4A patent/EP2134341B1/en not_active Not-in-force
- 2008-02-11 US US12/069,533 patent/US20080207640A1/en not_active Abandoned
- 2008-02-13 TW TW097104956A patent/TWI450719B/zh active
-
2009
- 2009-08-12 IL IL200367A patent/IL200367A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008100448A3 (en) | 2008-10-23 |
| EP2134341A2 (en) | 2009-12-23 |
| EP2134341A4 (en) | 2011-08-17 |
| TWI450719B (zh) | 2014-09-01 |
| TW200914019A (en) | 2009-04-01 |
| CN101686966A (zh) | 2010-03-31 |
| US20080207640A1 (en) | 2008-08-28 |
| IL200367A0 (en) | 2010-04-29 |
| EP2134341B1 (en) | 2015-06-17 |
| AU2008216789A1 (en) | 2008-08-21 |
| WO2008100448A2 (en) | 2008-08-21 |
| MX2009008561A (es) | 2010-01-15 |
| JP2010518158A (ja) | 2010-05-27 |
| KR20090112720A (ko) | 2009-10-28 |
| EA200970764A1 (ru) | 2010-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20140210 |