CA2668923C - Use of tri-substituted glycerol compounds for the treatment of radiation injuries - Google Patents

Use of tri-substituted glycerol compounds for the treatment of radiation injuries Download PDF

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Publication number
CA2668923C
CA2668923C CA2668923A CA2668923A CA2668923C CA 2668923 C CA2668923 C CA 2668923C CA 2668923 A CA2668923 A CA 2668923A CA 2668923 A CA2668923 A CA 2668923A CA 2668923 C CA2668923 C CA 2668923C
Authority
CA
Canada
Prior art keywords
radiation
tri
substituted glycerol
glycerol compound
dosage form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2668923A
Other languages
English (en)
French (fr)
Other versions
CA2668923A1 (en
Inventor
Wolfgang Richter
Lutz Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Radioprotect Alphaptose Ug (haftungsbeschraenkt) & Co KG
Original Assignee
Radioprotect Alphaptose Ug (haftungsbeschraenkt) & Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radioprotect Alphaptose Ug (haftungsbeschraenkt) & Co KG filed Critical Radioprotect Alphaptose Ug (haftungsbeschraenkt) & Co KG
Publication of CA2668923A1 publication Critical patent/CA2668923A1/en
Application granted granted Critical
Publication of CA2668923C publication Critical patent/CA2668923C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/106Adducts, complexes, salts of phosphatides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA2668923A 2006-11-10 2007-11-09 Use of tri-substituted glycerol compounds for the treatment of radiation injuries Expired - Fee Related CA2668923C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85817006P 2006-11-10 2006-11-10
US60/858,170 2006-11-10
PCT/EP2007/062181 WO2008055997A1 (en) 2006-11-10 2007-11-09 Use of tri-substituted glycerol compounds for the treatment of radiation injuries

Publications (2)

Publication Number Publication Date
CA2668923A1 CA2668923A1 (en) 2008-05-15
CA2668923C true CA2668923C (en) 2015-01-13

Family

ID=38904569

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2668923A Expired - Fee Related CA2668923C (en) 2006-11-10 2007-11-09 Use of tri-substituted glycerol compounds for the treatment of radiation injuries

Country Status (9)

Country Link
US (1) US20100130449A1 (https=)
EP (1) EP2089401B1 (https=)
JP (2) JP5512275B2 (https=)
AU (1) AU2007316589B2 (https=)
CA (1) CA2668923C (https=)
DK (1) DK2089401T3 (https=)
ES (1) ES2391659T3 (https=)
RU (1) RU2448973C2 (https=)
WO (1) WO2008055997A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2448973C2 (ru) * 2006-11-10 2012-04-27 Альфаптозе ГмбХ Применение соединений три-замещенного глицерина для лечения радиационных поражений
JP6411725B2 (ja) 2013-10-31 2018-10-24 株式会社Nttドコモ 無線基地局、ユーザ端末および無線通信方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3827974A1 (de) * 1988-08-18 1990-02-22 Boehringer Mannheim Gmbh Kombinationspraeparate von proteinkinase-c-inhibitoren mit lipiden, lipid-analoga, cytostatica oder inhibitoren von phospholipasen
DE3918082A1 (de) * 1989-06-02 1991-01-24 Max Planck Gesellschaft Mittel gegen autoimmunerkrankungen
US5082846A (en) * 1990-08-30 1992-01-21 Sandoz Ltd. Use of the R-(+)-isomer of 2-methoxy-3-octadecyloxy-propanol-(1)-phosphoric acid, monocholine ester in treating multiple sclerosis
DE19822509A1 (de) * 1998-05-19 1999-11-25 Medmark Pharma Gmbh Edelfosin zur Behandlung von Hirntumoren
US20020102208A1 (en) * 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
SE517142C2 (sv) * 2000-04-11 2002-04-23 Delaval Holding Ab Utfodringsanordning samt arrangemang och förfarande för automatisk mjölkutfodring
WO2005020935A2 (en) * 2003-02-06 2005-03-10 Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Method and composition of administering radioprotectants
RU2448973C2 (ru) * 2006-11-10 2012-04-27 Альфаптозе ГмбХ Применение соединений три-замещенного глицерина для лечения радиационных поражений

Also Published As

Publication number Publication date
JP2013227341A (ja) 2013-11-07
CA2668923A1 (en) 2008-05-15
WO2008055997A1 (en) 2008-05-15
JP5512275B2 (ja) 2014-06-04
AU2007316589A1 (en) 2008-05-15
AU2007316589B2 (en) 2013-03-07
ES2391659T3 (es) 2012-11-28
EP2089401B1 (en) 2012-07-25
RU2009121836A (ru) 2010-12-20
US20100130449A1 (en) 2010-05-27
JP2010509294A (ja) 2010-03-25
RU2448973C2 (ru) 2012-04-27
DK2089401T3 (da) 2012-09-17
EP2089401A1 (en) 2009-08-19

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20201109